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Not yet recruitingNCT07866898Updated Oct 8, 2026

Peripheral Nerve Ultrasound in Children With Guillain-Barré Syndrome

An observational study in Guillain-Barre Syndrome, sponsored by Assiut University. Not yet recruiting. Open to participants aged 1 Year to 17 Years. Per ClinicalTrials.gov, last updated 2026-10-08.

Sponsored by Assiut University · Observational

Updated Oct 8, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
42
Ages
1 Year to 17 Years
Sex
All
01

Study summary

This prospective observational study aims to evaluate peripheral nerve ultrasound findings, particularly nerve cross-sectional area, in children with Guillain-Barré syndrome.

Read the detailed description

Guillain-Barré syndrome is an acute immune-mediated neuropathy. High-resolution peripheral nerve ultrasound can measure nerve cross-sectional area and detect structural abnormalities.

This observational study will perform peripheral nerve ultrasound and nerve conduction studies in children aged 1 to 17 years with Guillain-Barré syndrome at baseline and at 3 months.

02

Conditions studied

  • Guillain-Barre Syndrome

Keywords

  • Guillain-Barre syndrome
  • Peripheral nerve ultrasound
  • Nerve cross-sectional area
  • Children
  • Assiut
03

In context

Guillain-Barre Syndrome

85 studies on the registry are indexed under Guillain-Barre Syndrome; 29 are open to participants now.

This study's planned enrollment of 42 is below the median of 100 across 41 observational studies indexed under Guillain-Barre Syndrome.

Browse Guillain-Barre Syndrome studies →

Lead sponsor

Assiut University is the lead sponsor of 4,916 studies on the registry; 2,113 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Year to 17 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Children aged 1 to 17 years diagnosed with Guillain-Barré syndrome admitted to or evaluated at Assiut University Children's Hospital.

Inclusion criteria

  • - Age 1 to 17 years
  • Diagnosis compatible with Guillain-Barré syndrome according to Brighton criteria
  • Written informed consent from parent or legal guardian

Exclusion criteria

Exclusion Criteria:

  • Previous diagnosis of hereditary peripheral neuropathy
  • Chronic inflammatory demyelinating polyneuropathy or another chronic neuropathy
  • Previous neuromuscular disease affecting nerve conduction or ultrasound measurements
  • Significant peripheral nerve trauma or previous nerve surgery
  • Drug-induced neuropathy
  • Local anatomical abnormalities or marked edema preventing reliable ultrasound assessment
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
42 participants (estimated)
Patient registry
No

Groups and cohorts

  • Children with Guillain-Barré Syndrome

    Children aged 1 to 17 years with Guillain-Barré syndrome undergoing peripheral nerve ultrasound and nerve conduction studies.

06

What researchers measure

Primary outcomes

  1. Mean nerve cross-sectional area

    Mean cross-sectional area of selected peripheral nerves measured by high-resolution ultrasound in mm².

    Time frame: Baseline

Secondary outcomes

  1. Change in nerve cross-sectional area

    Mean change in peripheral nerve cross-sectional area in mm² from baseline to 3 months.

    Time frame: At 3 months

  2. Mean distal motor latency

    Mean distal motor latency measured by nerve conduction study in milliseconds.

    Time frame: Baseline

  3. Mean compound muscle action potential amplitude

    Mean compound muscle action potential amplitude measured by nerve conduction study in millivolts.

    Time frame: Baseline

  4. GBS Disability Scale Score

    Mean Guillain-Barré Syndrome disability scale score (range 0 to 6, higher scores indicate worse disability).

    Time frame: Baseline

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 8, 2026
Show all 1 update
  1. Oct 8, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07866898
Lead sponsor
Assiut University
Responsible party
Ahmed Sultan Ahmed Shetawy (Resident Physician, Department of Pediatrics, Assiut University) — Principal investigator
First posted
Oct 8, 2026
Start date
Oct 10, 2026 (estimated)
Primary completion
Oct 10, 2027 (estimated)
Completion
Feb 1, 2028 (estimated)
Last update
Oct 8, 2026

Study contacts

Ahmed S Ahmed, Resident
Contact
as99709@gmail.com
+20 12 70363133
Azza A Eltayeb, prof
study chair · Pediatrics Department, Assiut University Hospitals

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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