An observational study in Pre-Eclampsia and Asymptomatic Bacteriuria, sponsored by Assiut University. Not yet recruiting. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-10-08.
Sponsored by Assiut University · Observational
Pre-eclampsia is a hypertensive disorder of pregnancy that can lead to significant health complications for both the mother and the fetus. Asymptomatic bacteriuria (ASB) occurs when significant amounts of bacteria are present in the urinary tract without causing symptoms such as burning, pain, or fever. Research suggests that persistent, asymptomatic bacterial growth can stimulate inflammatory responses and endothelial dysfunction, which may contribute to or worsen pre-eclampsia. However, local data regarding how frequently this condition occurs among pre-eclamptic women in Assiut remains limited.
The primary purpose of this cross-sectional study is to determine the prevalence of asymptomatic bacteriuria among pregnant women diagnosed with pre-eclampsia admitted to or attending the Department of Obstetrics and Gynecology at Women's Health Hospital, Assiut University. The study also aims to identify the specific bacterial species responsible for these infections, assess their antibiotic susceptibility profiles, and evaluate potential sociodemographic and clinical risk factors.
Enrolled participants will be asked to complete a structured interview questionnaire regarding their medical history, obstetric history, and sociodemographic details. Each participant will provide a single clean-catch midstream urine sample for quantitative urine culture and microbiological analysis. Positive culture results will be communicated to the treating clinical team to guide targeted antibiotic management.
882 studies on the registry are indexed under Pre-Eclampsia; 237 are open to participants now.
This study's planned enrollment of 129 is below the median of 163 across 380 observational studies indexed under Pre-Eclampsia.
Browse Pre-Eclampsia studies →Assiut University is the lead sponsor of 4,916 studies on the registry; 2,113 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Pregnant women diagnosed with pre-eclampsia attending the inpatient wards and outpatient clinics of the Department of Obstetrics and Gynecology at Women's Health Hospital, Assiut University Hospitals, who are at 20 or more weeks of gestation and present without clinical symptoms of a urinary tract infection.
Exclusion Criteria:
Pregnant women aged 18 to 45 years at 20 or more weeks of gestation diagnosed with pre-eclampsia and presenting without clinical symptoms of a urinary tract infection. All participants complete a structured questionnaire covering sociodemographic and obstetric data and provide a clean-catch midstream urine specimen for quantitative culture, bacterial identification, and antimicrobial susceptibility testing.
Percentage of Participants With Asymptomatic Bacteriuria
Asymptomatic bacteriuria is defined as significant bacterial growth (≥10\^5 CFU/mL of a single bacterial pathogen) isolated from a clean-catch midstream urine culture in the absence of urinary tract infection symptoms. It will be calculated as the number of pre-eclamptic pregnant women with confirmed bacteriuria divided by the total number of enrolled participants, expressed as a percentage.
Time frame: Baseline
No study locations are listed for this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Assiut University