A Phase 4 interventional study of Tamsulosin 0.4 MG and Control in Urolithiasis, Tamsulosin and Pre-operative, sponsored by Singapore General Hospital. Completed at 2 sites in Singapore. Open to participants aged 21 Years and older. Per ClinicalTrials.gov, last updated 2026-09-29.
Sponsored by Singapore General Hospital · Phase 4, Interventional, and Treatment
The goal of this clinical trial is to assess whether tamsulosin given one week prior to renal or ureteric stone surgery would improve the success rate of ureteral access sheath deployment and decrease ureteral injury
278 studies on the registry are indexed under Urolithiasis; 70 are open to participants now.
This study's enrollment of 111 is above the median of 100 across 197 interventional studies indexed under Urolithiasis.
Browse Urolithiasis studies →Singapore General Hospital is the lead sponsor of 266 studies on the registry; 57 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Treatment with one week pre-operative tamsulosin
Drug: Tamsulosin 0.4 MG
Control arm
Drug: Control
Pre-operative tamsulosin 400mcg for one week prior to operation
Control, no medication (standard of care)
UAS placement success
Successful placement of a ureteral access sheath during index procedure
Time frame: At the time of operation
operative duration
Time frame: operation date, start time and end time
ureteral injury
graded according to the post-ureteroscopic lesion scale (PULS)
Time frame: intraoperative
Stone-free rate (SFR)
Imaging evaluation for SFR using XR KUB or NCCT KUB
Time frame: 90 days postoperatively
Medication adverse effects
Patient reported adverse effects
Time frame: pre-operatively 1 week until operation date
Documents are hosted by the registry — open the source record to download them.
Plan to share: No
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Singapore General Hospital