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RecruitingNCT07847502IC-TENS-CSUpdated Sep 29, 2026

Interferential Current and TENS for Pain After Cesarean Section

An interventional study of Conventional Transcutaneous Electrical Nerve Stimulation and Interferential Current Therapy in Postoperative Pain After Cesarean Section, sponsored by Dilara Özen Oruk. Recruiting at 1 site in Turkey (Türkiye). Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-09-29.

Sponsored by Dilara Özen Oruk · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
54
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
Female
01

Study summary

This study aims to compare the immediate and short-term effects of interferential current therapy and conventional transcutaneous electrical nerve stimulation (TENS) with placebo stimulation on pain and postpartum comfort following cesarean section. A total of 54 primiparous women aged 18-40 years will be randomly assigned to an interferential current, TENS, or placebo group. Each intervention will be administered for 30 minutes. Pain intensity at rest and during in-bed activities will be assessed before the intervention, immediately after the intervention, and at 1 and 2 hours after the intervention. Postpartum comfort, treatment satisfaction, anxiety, and depression will also be evaluated.

Read the detailed description

This is a prospective, randomized, placebo-controlled, three-arm clinical trial conducted in the Obstetrics and Gynecology Department of Menteşe State Hospital. The study will include 54 primiparous women following cesarean section. Eligible participants who provide written informed consent will be randomly allocated to the conventional TENS group, interferential current therapy group, or placebo stimulation group.

All interventions will be administered in the supine position with a pillow placed under the knees. Four self-adhesive electrodes will be positioned around the cesarean incision. Conventional TENS will be applied at a frequency of 125 Hz and a pulse duration of 60 microseconds. Interferential current therapy will be applied using a fixed frequency of 100 Hz. In both active intervention groups, current intensity will be increased to a strong but comfortable sensory level and adjusted throughout the session to maintain the same sensation. In the placebo group, the electrodes and device will be applied in the same manner, but no electrical current will be delivered. Each intervention will last 30 minutes.

An assessor blinded to group allocation will perform all evaluations. Pain intensity at rest and during in-bed activities will be assessed using separate 0-10 cm visual analog scales before the intervention, immediately after the intervention, and at 1 and 2 hours after the intervention. Postpartum comfort will be evaluated before the intervention and 2 hours after the intervention using the Postpartum Comfort Questionnaire. Treatment satisfaction will be assessed immediately, 1 hour, and 2 hours after the intervention. Baseline anxiety and depression levels will be evaluated using the Hospital Anxiety and Depression Scale.

02

Conditions studied

  • Postoperative Pain After Cesarean Section

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Keywords

  • Transcutaneous Electrical Nerve Stimulation
  • TENS
  • Interferential Current Therapy
  • Cesarean Delivery
  • Postpartum Comfort
  • Acute Postoperative Pain
  • Nonpharmacological Pain Management
03

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Women aged 18 to 40 years
  • Ability to read, write, and communicate in Turkish
  • Primiparous women
  • Having delivered a healthy singleton infant by cesarean section
  • No additional surgical procedure or complication during or after the cesarean section

Exclusion criteria

Exclusion Criteria:

  • Impaired orientation or cooperation
  • History of systemic disorders, including hyperglycemia or hypertension, gastrointestinal disorders, or urogynecological disorders
  • Previous abdominal surgery
  • Neurological, orthopedic, cardiopulmonary, or other health conditions that may prevent mobilization or ambulation
  • Previous experience with transcutaneous electrical nerve stimulation or interferential current therapy
  • Contraindications to electrical stimulation, including sensory loss at the application site, dermatological problems or allergic reactions at the application site, or a cardiac pacemaker
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
54 participants (estimated)

Study arms

  • Active comparator
    Conventional TENS

    Participants will receive one 30-minute session of conventional transcutaneous electrical nerve stimulation following cesarean section.

    Device: Conventional Transcutaneous Electrical Nerve Stimulation

  • Experimental
    Interferential Current Therapy

    Participants will receive one 30-minute session of interferential current therapy following cesarean section.

    Device: Interferential Current Therapy

  • Placebo comparator
    Placebo Stimulation

    Participants will receive one 30-minute session of placebo electrical stimulation following cesarean section.

    Device: Placebo Electrical Stimulation

Interventions

  • DeviceConventional Transcutaneous Electrical Nerve Stimulation

    Conventional TENS will be applied for 30 minutes at a frequency of 125 Hz and a pulse duration of 60 microseconds. Four self-adhesive electrodes will be positioned around the cesarean incision. Current intensity will be increased to a strong but comfortable sensory level and adjusted during the session to maintain the same sensation.

  • DeviceInterferential Current Therapy

    Interferential current therapy will be applied for 30 minutes using a fixed frequency of 100 Hz. Four self-adhesive electrodes will be positioned around the cesarean incision in a crossed arrangement. Current intensity will be increased to a strong but comfortable sensory level and adjusted during the session to maintain the same sensation.

    Also known as: IFC

  • DevicePlacebo Electrical Stimulation

    The electrodes and stimulation device will be applied in the same position and for the same 30-minute duration as in the active intervention groups; however, no electrical current will be delivered.

    Also known as: Sham Stimulation

05

What researchers measure

Primary outcomes

  1. Change in Pain Intensity at Rest

    Pain intensity at rest will be assessed using a 10-cm Visual Analog Scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity. Changes from baseline will be compared among the three groups.

    Time frame: Baseline, immediately after the 30-minute intervention, 1 hour after the intervention, and 2 hours after the intervention

Secondary outcomes

  1. Change in Postpartum Comfort

    Postpartum comfort will be assessed using the Postpartum Comfort Questionnaire. The questionnaire contains 34 items covering physical, psychospiritual, and sociocultural comfort. Total scores range from 34 to 170, with higher scores indicating greater postpartum comfort.

    Time frame: Baseline and 2 hours after the intervention

  2. Treatment Satisfaction

    Treatment satisfaction will be assessed using a 10-cm Visual Analog Scale ranging from 0 (not satisfied at all) to 10 (very satisfied). Higher scores indicate greater treatment satisfaction.

    Time frame: Immediately after the intervention, 1 hour after the intervention, and 2 hours after the intervention

Other outcomes

  1. Association Between Psychological Symptoms and Change in Pain Intensity

    Anxiety and depression symptoms will be assessed at baseline using the Hospital Anxiety and Depression Scale. The scale consists of 14 items divided into anxiety and depression subscales, each ranging from 0 to 21. Higher scores indicate greater symptom severity. The associations between baseline anxiety and depression scores and changes in pain intensity following the interventions will be examined.

    Time frame: From baseline to 2 hours after the intervention

06

Study locations

1 of 1 sites recruiting
  • Menteşe State Hospital
    Muğla, 48000, Turkey (Türkiye)
    Recruiting
07

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be made publicly available because the dataset contains sensitive obstetric and health information, and public data sharing was not included in the informed consent process.

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07847502
Lead sponsor
Dilara Özen Oruk
Responsible party
Dilara Özen Oruk (Research Assistant, PhD, Muğla Sıtkı Koçman University) — Sponsor-investigator
First posted
Sep 29, 2026
Start date
Mar 4, 2026
Primary completion
Feb 1, 2027 (estimated)
Completion
Feb 1, 2027 (estimated)
Last update
Sep 29, 2026

Study contacts

Dilara Özen Oruk, PhD
Contact
dilaraozen@mu.edu.tr
+902522112072
Dilara Özen Oruk, PhD
principal investigator · Muğla Sıtkı Koçman University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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