An interventional study of combined Nasal goniotomy-Temporal trabeculotomy and Temporal trabeculotomy in Primary Congenital Glaucoma, sponsored by Zagazig University. Completed at 1 site in Egypt. Open to participants aged 1 Day to 2 Years. Per ClinicalTrials.gov, last updated 2026-09-21.
Sponsored by Zagazig University · Not applicable, Interventional, and Treatment
Among 11 studies in Hydrophthalmos with a site in Egypt — none open to participants now, 1 under way, none of them phase 3. Hydrophthalmos · Egypt.
Among the 11 studies in Hydrophthalmos with a site in Egypt, this one is the 9th largest by enrollment of the 10 interventional ones that give a count, is one of 3 that started in 2024, is one of 9 with no phase, and was the 10th registered.
37 studies on the registry are indexed under Hydrophthalmos; 3 are open to participants now.
Browse Hydrophthalmos studies →None of the 11 studies in Hydrophthalmos with a site in Egypt is open now. The open studies under Hydrophthalmos, anywhere →
This tab as a report to print or save as PDF → With an account.
11 studies; the count open now beside each. This study's row is marked.
First in 2015; this study’s year is marked. 3 started in 2024.
This study's enrollment of 21 is below the median of 37 across 29 interventional studies indexed under Hydrophthalmos.
Median enrollment 33 across the 10 interventional studies, 150 across the 1 observational. Of the 7 that completed or were terminated, 0 (0%) have results posted.
This tab as a report to print or save as PDF → With an account.
None of the 11 has an industry lead sponsor. The 8 most frequent:
Zagazig University is the lead sponsor of 459 studies on the registry; 77 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Zagazig University has 1 study filed under Hydrophthalmos — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 11 studies in Hydrophthalmos with a site in Egypt, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
Combined nasal goniotomy and temporal trabeculotomy provides effective IOP control in PCG while preserving the superior conjunctiva for future filtering procedures. By expanding the treated angle area and sparing the superior conjunctiva, this operation provides a synergistic approach that may improve long-term management strategies for pediatric glaucoma
Primary congenital glaucoma (PCG) is the main category of primary childhood glaucoma. Classically, PCG presents with one or more of the following clinical manifestations: increased corneal diameters, corneal opacification, photophobia, and excessive tearing. The increased intraocular pressure (IOP) in PCG is mainly due to an immature anterior chamber (AC) angle with inadequate aqueous filtration through the trabecular meshwork (TM). 1 Reduction of IOP in PCG relies mainly on surgical treatment. Wide variations in surgical procedures exist for the treatment of PCG, with different principles and steps. The idea behind angle-based surgeries is to remove the main barrier to aqueous filtration and create a direct pathway for aqueous to reach the Schlemm's Canal (SC). Other surgeries, such as trabeculectomy or implantation of Glaucoma drainage devices (GDD), divert the aqueous drainage toward the sub-tenon space away from the occluded TM.2,3 and 4 PCG treatment may entail the need for more than one surgery to correct the IOP. Combining two or more surgical procedures in the same setting may produce a synergistic effect in reducing the IOP while reducing the psychological and surgical burden on PCG patients. In the combined Nasal Goniotomy-Temporal Trabeculotomy (NGTT) procedure, preservation of the superior conjunctiva is an advantage that increases the success rates of further surgeries if needed. 5 In this study, the authors studied a real-world comparison between NGTT and single-site trabeculotomy for the management of PCG patients.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
combined nasal goniotomy-Temporal trabeculotomy
Procedure: combined Nasal goniotomy-Temporal trabeculotomy
Temporal trabeculotomy
Procedure: Temporal trabeculotomy
Temporal trabeculotomy
Temporal trabeculotomy
intra ocular pressure
post operative IOP compared to preoperative IOP
Time frame: 1 YEAR
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Feb 2024 to primary completion in Feb 2026, 24 months.
Of 11 interventional studies with no phase under Hydrophthalmos, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 22 and three quarters within 25. This study's 24 months is close to that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.