An interventional study of Group Interpersonal Therapy (IPT-G) and Enhanced treatment as usual in Depression - Major Depressive Disorder, sponsored by IDinsight. Active, not recruiting at 1 site in Uganda. Open to participants aged 15 Years and older. Per ClinicalTrials.gov, last updated 2026-09-10.
Sponsored by IDinsight · Not applicable, Interventional, and Treatment
Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →
Among 10 studies in Psychological Well-Being with a site in Uganda — 3 open to participants now, 6 under way, none of them phase 3. Psychological Well-Being · Uganda.
Among the 10 studies in Psychological Well-Being with a site in Uganda, this one is the 4th largest by enrollment, is one of 4 that started in 2026, is one of 10 with no phase, and was the 10th registered.
2,195 studies on the registry are indexed under Psychological Well-Being; 728 are open to participants now.
Browse Psychological Well-Being studies →3 of the 10 studies in Psychological Well-Being with a site in Uganda are open now. Recruiting first, the newest first:
Yale University · Sites in Uganda
Ages 18+
University of California, San Francisco · Sites in Uganda
Ages 0 days+
NYU Langone Health · Sites in Uganda
Ages 18–65 · Healthy volunteers
A study can be open while its sites in Uganda have not opened yet or have stopped. Only those recruiting at a site in Uganda →
Of the 401 Psychological Well-Being studies recruiting now, 218 (54%) set no upper age limit and 157 (39%) stop at 75 or younger; 120 take children under 18; 204 take healthy volunteers.
This study: 15 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
10 studies; the count open now beside each. This study's row is marked.
First in 2012; this study’s year is marked. 4 started in 2026.
This study's enrollment of 1,213 is above the median of 110 across 1,798 interventional studies indexed under Psychological Well-Being.
Median enrollment 900 across the 10 interventional studies. Of the 4 that completed or were terminated, 1 (25%) have results posted.
This tab as a report to print or save as PDF → With an account.
None of the 10 has an industry lead sponsor. The 8 most frequent:
IDinsight is the lead sponsor of 7 studies on the registry; 1 is open to participants now.
IDinsight has 1 study filed under Psychological Well-Being — fewer than ten, so there is no comparison to draw.
3 of the studies in Psychological Well-Being with a site in Uganda that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07062341Uppsala UniversitySelf-Help Plus to Enhance Early Development: A Cluster-Randomized Controlled Trial of Maternal Mental Health, Child Cognitive Abilities, and Socio-Behavioral Skills Among Refugee Mothers and Their Preschool-Aged Children in Rhino Camp, Uganda | 2027-02 |
| NCT07812311IDinsightEvaluating the Effects of StrongMinds Community-Based Group Interpersonal Therapy on Depression and Secondary Outcomes in Uganda | 2027-04-09 |
| NCT07774793University of California, San FranciscoRelaxation Intervention to Improve Newborn Growth and Maternal Well-being | 2027-05 |
Add all 3 to your calendar (.ics) → With an account.
Among the 10 studies in Psychological Well-Being with a site in Uganda, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study aims to evaluate the impact of the StrongMinds Group Interpersonal Therapy (IPT-G) program on depressive symptoms (primary outcome) and measures related to quality of life, social, economic, educational outcomes, and within-household spillover effects (secondary outcomes). This study is a two-arm, parallel, cluster-randomized controlled trial (RCT) in which villages serve as the unit of randomization. 100 villages across two districts in Uganda, Luuka and Buikwe, have been randomly assigned in equal proportion to one of two conditions: (1) a treatment arm, in which eligible participants receive StrongMinds' 6-week community-based IPT-G program, or (2) a control arm, in which eligible participants receive enhanced-treatment-as-usual (ETAU), involving psychoeducation and referral to a nurse.
Primary hypothesis: Participants in villages randomized to receive IPT-G will exhibit a significantly greater reduction in Patient Health Questionnaire-9 (PHQ-9) depression scores at 6 months post-treatment compared to participants in ETAU villages.
See attached study protocol for more details.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Individuals excluded due to suicidal ideation or GBV will be referred to appropriate services (see Section 2.10) and will not be enrolled in the study. Individuals with active suicidal ideation will be excluded because group IPT-G cannot provide the individualized monitoring and crisis response that acute suicidality requires.These exclusions are intended to ensure participant safety and do not preclude individuals from receiving StrongMinds services outside the study context.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
IPT-G
Behavioral: Group Interpersonal Therapy (IPT-G)
Enhanced-Treatment-As-Usual (ETAU): psychoeducation and referral to a government nurse
Behavioral: Enhanced treatment as usual
IPT-G is a structured, time-limited psychotherapy that focuses on resolving interpersonal difficulties such as grief, role disputes, role transitions, and social isolation. These difficulties are causally linked to the onset and maintenance of depressive episodes. StrongMinds implements an adapted version of IPT-G tailored to the Ugandan context. It involves a six-week program where trained lay workers facilitate weekly group therapy sessions under supervision of trained staff. The intervention's community-based nature allows it to address cultural and logistical barriers to mental health care, fostering greater accessibility and sustainability. In this RCT, we are assessing delivery of IPT-G to four target groups: adult women, adult men, adolescent males, and adolescent females.
Eligible participants in the control group receive enhanced-treatment-as-usual (ETAU), involving psychoeducation and referral to a nurse.
Depression severity (PHQ-9)
Score on the Patient Health Questionnaire-9 (PHQ-9). The PHQ-9 is a validated 9-item self-report measure of depression severity over the past two weeks, scored 0 (minimal or no depressive symptoms) to 27 (severe depressive symptoms).
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Generalized Anxiety Disorder
GAD-7: A 7-item measure of anxiety severity, rated from 0 (minimal anxiety) to 21 (severe anxiety)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Male Depression
Male Depression Risk Scale (MDRS-7): A 7-item multidimensional depression rating scale capturing other behaviors associated with depression, rated from 0 (minimal depression) to 28 (severe depression)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Stress overload
Stress Overload Scale (SOS): A 4-item scale measuring perceived stress and feelings of being overwhelmed, rated from 0 (minimal stress) to 16 (severe stress)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Disability and functional impairment
World Health Organization Disability Assessment Schedule (WHODAS 2.0, 12-item): A measure of functional impairment across six domains (cognition, mobility, self-care, getting along, life activities, participation), rated from 0 (minimal functional impairment) to 48 (severe functional impairment)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Subjective well-being
Cantril Self-Anchoring Ladder: A single-item measure of subjective well-being, rated from 0 (worst possible life) to 10 (best possible life)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Positive affect well-being
World Health Organization Well-Being Index (WHO-5): A 5-item positive-affect wellbeing measure on mood, calmness, energy, sleep quality, and daily interest, rated from 0 (very poor well-being) to 25 (very good well-being)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Perceived social support
Multidimensional Scale of Perceived Social Support (MSPSS) Reduced Scale: A 6-item measure of perceived support from family, friends, and significant others, rated from 6 (very limited social support) to 30 (very strong social support)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Labor market participation (1)
Labor supply: days worked in the past week
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Household income
Household monthly income
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Nutrition (1)
Nutrition: Number of meals consumed in the past 24 hours (self)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Household consumption
Household consumption: Total value of household consumption (in Ugandan shillings), aggregated from a list of 12 commonly-consumed items.
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Decision-making
Decision-making: A 9-item scale to measure of indecision and choice avoidance, rated from 9 (very indecisive) to 45 (very decisive)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Labor market participation (2)
Labor supply: average number of hours worked per day in the previous week
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Self-efficacy
Self efficacy: A 5-item scale of self-efficacy, rated from 5 (minimal self-efficacy) to 25 (maximum self-efficacy)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Nutrition (2)
Nutrition: Number of meals consumed in the past 24 hours (average across children in the household)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
Nutrition (3)
Nutrition: Food insecurity, as measured on the 3-item Household Hunger Scale (HHS), rated from 0 (little or no hunger) to 6 (severe hunger)
Time frame: Enrollment (pre-intervention), 2-weeks post-intervention, 6-months post-intervention, (potentially) 12-months post-intervention, (potentially) 24-months post-intervention
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Yes — All data collected from participants will be anonymized and posted on a public dataverse.
Supporting information: Study protocol
Time frame: IPD will be shared approximately six months after study completion (likely in 2028) and will be available indefinitely.
Access criteria: The anonymized study data will be shared on the Harvard Dataverse.
Started Jul 2026 (actual). Primary completion is estimated for Apr 2027, 9 months after the start.
Of 1,261 non-industry interventional studies with no phase under Psychological Well-Being, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 34. This study's planned 9 months is below that.
Counting every sponsor, half of 1,304 studies reached it within 16 months; a quarter within 7 and three quarters within 34.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
IDinsight