ClinicalTrials.gg
RecruitingNCT07913854Updated Nov 3, 2026

Exploring The Effect of TikTok Trigger Warnings in a Clinical Sample of Youth at Risk of Suicide

An interventional study of Trigger Warning in Suicide Prevention and Social Media Users, sponsored by Sunnybrook Health Sciences Centre. Recruiting at 1 site in Canada. Open to participants aged 14 Years to 19 Years. Per ClinicalTrials.gov, last updated 2026-11-03.

Sponsored by Sunnybrook Health Sciences Centre · Not applicable, Interventional, and Prevention

Updated Nov 3, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
82
Allocation
Randomized
Ages
14 Years to 19 Years
Sex
All
01

Study summary

Rates of suicide among Canadian youth have risen steadily over the past two decades, alongside rapid growth in social media use-especially TikTok. Our research shows that TikTok contains substantial suicide-related content that may pose risks to vulnerable young people by provoking distress or encouraging copycat behaviour. Many creators add trigger warnings (TWs) to flag upsetting material, yet their impact is unclear. Although research shows mixed effects of TWs among people with trauma histories, no studies have examined TWs in the context of suicide-related content. Our recent findings indicate that TWs are associated with reduced engagement suicide-related videos on TikTok-contrary to our hypothesis that they might increase engagement. Although we can only speculate, reduced engagement may reflect youth avoiding TW-labelled content, or other unknown factors. This study will examine how a clinical population of youth at risk of suicide emotionally and behaviourally respond to TWs on self-harm and suicide-related content. Findings will provide key evidence to inform public health recommendations aimed at protecting youth from harmful content online.

Read the detailed description

7: Department of Psychiatry, Sunnybrook Health Science Centre, Toronto, Canada 8: National Council for Suicide Prevention, Minneapolis, Minnesota, USA Background: Suicide is the second leading cause of death among Canadian youth under 24. Social media, particularly TikTok, is widely used by Canadian youth, where suicide-related content is highly prevalent. Harmful content that glamorizes or normalizes suicide is especially concerning given its potential to contribute to social contagion-the spread of behaviours, emotions, and attitudes through social networks.

Trigger warnings (TWs), which alert viewers to potentially distressing material, are one strategy intended to mitigate the negative effects of exposure to suicide-related content. However, evidence regarding their effects on emotional responses and behavioural avoidance remains mixed. To date, no research has examined TWs specifically in relation to suicide-related social media content or among clinical populations at elevated risk for suicide. This study aims to examine the impact of TWs on affect and state anxiety among youth viewing suicide-related TikTok content.

Methods: Youth aged 14-19 years with a lifetime history of suicidal thoughts and/or behaviours, including passive suicidal ideation within the past 6 months, will be recruited (N = 82). Exclusion criteria include suicidal intent, planning, or behaviour within the past 6 months, as well as active psychosis or mania. Participants will be randomized 1:1 to view two expert-vetted, recovery-oriented TikTok videos featuring one male-appearing and one female-appearing protagonist, with the video order counterbalanced. Participants will view the videos either with (TW+) or without (TW-) a 6-second trigger warning.

Affect and state anxiety will be assessed immediately before and after viewing the TikTok videos using standardized measures (β = 0.80, α = .05, f = 0.20). Post-experiment questionnaires will also assess participants' perceptions of the utility of trigger warnings. Among participants in the TW+ condition, questionnaires will also assess intention to avoid the warned-about content and retrospectively rated anticipatory anxiety following exposure to the trigger warning.

Changes in affect and state anxiety will be analyzed using linear mixed-effects models examining the interaction between trigger warning condition and time (TW presence × time). Post-experiment outcomes will be analyzed using ANCOVAs, adjusting for relevant confounders. Outcomes will also be examined by sex and gender to identify patterns suggestive of potential sex- and gender-related differences.

Results: Preliminary results are expected to be available by the time of the symposium. We hypothesize that trigger warnings (TWs) presented before suicide-related TikTok videos will alter viewers' emotional responses compared with viewing the same videos without TWs.

Discussion: This study will provide novel evidence on how trigger warnings influence emotional and behavioural responses to suicide-related content among youth at elevated risk for suicide. The results may inform evidence-based recommendations for social media platforms and public health strategies aimed at promoting safer online environments for youth. They may also help guide clinical approaches to assessing and addressing the influence of social media on suicide risk and broader mental health outcomes.

02

Conditions studied

  • Suicide Prevention
  • Social Media Users

Keywords

  • Create Guidelines and Best Practices
  • Mental Health
  • Youth Mental Health
  • Suicide
  • Social Media
  • Trigger Warnings
03

In context

Suicide Prevention

186 studies on the registry are indexed under Suicide Prevention; 92 are open to participants now.

This study's planned enrollment of 82 is below the median of 140 across 167 interventional studies indexed under Suicide Prevention.

Browse Suicide Prevention studies →

Lead sponsor

Sunnybrook Health Sciences Centre is the lead sponsor of 584 studies on the registry; 135 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
14 Years to 19 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Lifetime or recent suicidal thoughts as measured on the Columbia Suicide Severity Rating Scale (C-SSRS)20 screening version. Defined as answering "YES" Question 2 on the C-SSRS with a lifetime and/or past month time-framing ("In your entire life, have you ever had any thoughts of killing yourself?" and/or "In the past month, have you had any thoughts of killing yourself?")
  • Self-identified consumer of short-form content on social media (e.g. Instagram reels, TikTok, YouTube Shorts) in the last year.
  • English comprehension

Exclusion criteria

Exclusion Criteria:

  • Suicidal ideation with any intent or plan in the last 6 months. Defined as answering "YES" on any one C-SSRS Question 3 to 5 with a past 6-months timeframe. Note: Suicidal ideation in the absence of intent or planning is not an exclusion criterion
  • Suicidal behaviour in the last 6 months. Defined as answering "YES" to C-SSRS Question 6 ("In your entire life, have you ever done anything, started to do anything, or prepared to do anything to end your life?") AND a 6-months follow up questions ("Was this within the past 6 months?"). Note: Lifetime suicidal behaviour (i.e. answering yes to only Question 6) is not an exclusion criterion
  • In active psychosis or mania, as indicated by patient's medical records
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
82 participants (estimated)

Study arms

  • Experimental
    TW+: Trigger warning before suicide-related videos

    In this arm, participants will view a Trigger Warning (TW: Suicide) before the suicide-related content (one male -presenting and one female-presenting).

    Behavioral: Trigger Warning

  • No intervention
    TW-: No Trigger Warning

    In this arm participants will not view a Trigger Warning before watching the suicide-related content (one male-presenting and one female-presenting).

Interventions

  • BehavioralTrigger Warning

    The intervention will be the presence of a Trigger Warning (i.e., TW: Suicide) at the start of two suicide-related videos. One video will be of a male-presenting creator, and the other of a female-presenting. Both videos are recovery centered, but neutral, therefore not overally hoepful/postive, but not negative. We hypothesize that the presence of a Trigger Warning will affect emotional and behavioral responses to the suicide-related content.

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What researchers measure

Primary outcomes

  1. Emotional Affect

    We will measure emotional affect using the International Positive and Negative Affect Schedule - Short Form (I-PANAS-SF), State Version. Participants will rate the extent to which they are presently experiencing five positive emotions (alert, inspired, determined, attentive, active) and five negative emotions (upset, hostile, ashamed, nervous, afraid).

    Time frame: Administered to both study groups immediately before and immediately after viewing both videos.

Secondary outcomes

  1. State Anxiety

    State Anxiety will be measured using the STAI-S. It measures trait and state anxiety. This describes a participants current but teporary emotional response to an external trigger. Definition provided by APA: "anxiety in response to a specific situation that is perceived as threatening or dangerous. State anxiety varies in intensity and fluctuates over time." Participants will rate the degree to which they currently feel: calm, tense, upset, relaxed, content, worried.

    Time frame: STAI-6 is administered immediately before and after viewing both videos (administered to both groups).

  2. Self-Reported Behavioural Avoidance Intention

    It is the desire to engage in behavioural avoidance of the TikTok video. It will be measured by one single question. That single question was created for the purposes of measuring participants' intention for behavioural avoidance in this study. Participants will be asked: "If you encountered videos like the ones you just watched while scrolling on social media, how likely would you be to skip or scroll past them without watching?", with responses rated on a scale from 1 ("not at all likely") to 5 ("extremely likely").

    Time frame: It will be measured post- TW and stimuli viewing, for participants in both arms.

Other outcomes

  1. Retrospectively rated anticipatory anxiety, defined as anxiety experienced in anticipation of viewing content, rated retrospectively

    It will be measured by one single question. That single question will be asked of participants in the TW+ group: "Thinking back, how anxious did you feel immediately after seeing "Trigger warning: Suicide"?" They will rate their anxiety on a scale from 1 ("not at all") to 5 ("extremely"). For this question, TW+ participants must retrospectively rate their anxiety (i.e. think back to the anxiety they felt at the time and rate it, rather than asking for their anxiety in the moment, after the TW).

    Time frame: Administered to the TW+ group after viewing both videos.

  2. Attitudes towards/opinions about the helpfulness of TWs

    Participants will complete a post-experiment questionnaire that, among some other questions, assesses perceptions on the helpfulness of trigger warnings, including their perceived helpfulness for emotionally preparing viewers, helping viewers make informed viewing decisions, allowing viewers to avoid unwanted content, and protecting individuals with a history of suicidal thoughts and/or behaviours from unexpectedly encountering distressing content.

    Time frame: Administered to both groups in the post-experiment

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Yes — De-indentified IPD information will be disseminated upon request, once results are available.

Supporting information: Statistical analysis plan

Time frame: When the manuscript is publlished we will note that IPD is available upon request. Therefore, there is no established timeframe for the aavailability of IPD.

Access criteria: Those who request access, with a valid justification as to why (e.g., re-analysis or secondary analysis).

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Nov 3, 2026
Show all 1 update
  1. Nov 3, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07913854
Responsible party
Sponsor
First posted
Nov 3, 2026
Start date
Nov 15, 2026 (estimated)
Primary completion
Aug 15, 2027 (estimated)
Completion
Dec 15, 2027 (estimated)
Last update
Nov 3, 2026

Study contacts

Zoe Shelton, B.A.
Contact
zoejacklyn.shelton@mail.utoronto.ca
4388703910
Caroline Milligan, H.BSc
Contact
caroline.milligan@sunnybrook.ca
416-347-9622
Rachel Mitchell, MD, MSc
principal investigator · University of Toronto; Sunnybrook Health Sciences Center

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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