ClinicalTrials.gg
CompletedNCT07805720Updated Sep 10, 2026

Acupressure for Pain and Anxiety After Cesarean Section

An interventional study of Acupressure and Sham Acupressure in Postoperative Pain, Postpartum Anxiety and Acupressure, sponsored by University of Medicine and Pharmacy at Ho Chi Minh City. Completed at 1 site in Vietnam. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-10.

Sponsored by University of Medicine and Pharmacy at Ho Chi Minh City · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 4 months after the study started (first participant enrolled Apr 2026, registered Sep 2026).

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Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years and older
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 14 studies in Pain, Postoperative with a site in Vietnam — 3 open to participants now, 3 under way, none of them phase 3. Pain, Postoperative · Vietnam.

Enrollment
7th of 14
60 · median 60
Started
2026
with 2 others
No phase
11 of 14
2 open now
Registered
13th of 14
by date
Lead sponsor
5 of 14
University of Medicine and Pharmacy at Ho Chi Minh City

Among the 14 studies in Pain, Postoperative with a site in Vietnam, this one is the 7th largest by enrollment, is one of 3 that started in 2026, is one of 11 with no phase, and was the 13th registered.

Pain, Postoperative

5,644 studies on the registry are indexed under Pain, Postoperative; 1,229 are open to participants now.

Browse Pain, Postoperative studies →

Open to participants now

3 of the 14 studies in Pain, Postoperative with a site in Vietnam are open now. Recruiting first, the newest first:

All 3 open studies →

A study can be open while its sites in Vietnam have not opened yet or have stopped. Only those recruiting at a site in Vietnam →

Who these studies take

Of the 678 Pain, Postoperative studies recruiting now, 241 (36%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.

This study: 18 Years and older · female · no healthy volunteers.

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02

Study summary

The goal of this clinical trial is to evaluate whether acupressure combined with standard post-operative modern medical care can reduce pain and anxiety in postpartum women after cesarean delivery under spinal anesthesia. The main questions it aims to answer are:

  • Does acupressure combined with standard care reduce post-cesarean pain more effectively than sham acupressure with standard care?
  • Does the combined approach reduce post-cesarean anxiety levels more effectively than sham acupressure with standard care?
  • What adverse effects may occur in participants receiving acupressure? Researchers will compare acupressure combined with standard care to sham acupressure combined with standard care to determine whether the active intervention provides additional benefits.

Participants will:

  • Receive acupressure (or sham acupressure at non-therapeutic points) for 3 days.
  • Receive standard post-operative modern medical pain management and care as prescribed by the hospital.
  • Be assessed for pain (VAS-P) and anxiety (VAS-A, STAI-Y1) at baseline (before intervention) and after 3 days of intervention.
Read the detailed description

This randomized, single-blind, controlled clinical trial aims to evaluate the effectiveness and safety of acupressure combined with standard modern care in postpartum women with pain and anxiety following cesarean delivery under spinal anesthesia.

Participants who meet the eligibility criteria will be randomly assigned to either the intervention group ( acupressure plus standard modern care) or the control group (sham acupressure plus standard modern care).

In the intervention group, participants will receive manual acupressure (using xoa, day, and an techniques) on three bilateral therapeutic points: Hegu (LI4), Neiguan (PC6), and Sanyinjiao (SP6). Before applying pressure, the surrounding tissue is rubbed (xoa) with the palm for 20-30 seconds. Then, the points are pressed (an) for 5 seconds at a depth of 1-1.5 cm, kneaded (day) for 5 seconds, and rested for 5 seconds, repeating this cycle for 2 minutes per point. The total duration is 15 minutes for 6 points, performed once daily for 3 consecutive days.

In the control group, participants will receive sham acupressure (xoa, day, an) at identical frequencies and durations on 3 non-therapeutic sham points: Sham Hegu, Sham Neiguan, and Sham Sanyinjiao.

Both groups will receive standard post-operative modern pain management as prescribed by the hospital's obstetricians, which includes:

  • Post-op Day 1: Paracetamol 1g IV q6-8h ± Diclofenac 100mg rectally q12h;
  • Post-op Day 2 onwards: Paracetamol 1g PO q8h ± Diclofenac 100mg rectally q12h or other NSAIDs (such as Diclofenac 50mg, Ibuprofen 600-1200mg/day, Paracetamol + Ibuprofen, or Paracetamol + Tramadol) as prescribed by the hospital.

Outcomes including pain (VAS-P), anxiety (VAS-A, STAI-Y1), and any adverse events will be assessed at baseline (T1, pre-intervention) and after 3 days of intervention (T2).

03

Conditions studied

  • Postoperative Pain
  • Postpartum Anxiety
  • Acupressure

Keywords

  • Acupressure
  • Cesarean Section
  • Anxiety
  • Postoperative Pain
  • LI4
  • PC6
  • SP6
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Postpartum women aged 18 years or older who have undergone cesarean delivery with spinal anesthesia.
  • Gestational age >= 37 weeks.
  • Willing to participate and signing the written form.

Exclusion criteria

Exclusion Criteria:

  • General anesthesia or methods other than spinal anesthesia.
  • Hearing, vision, or speech impairment.
  • History of chronic diseases such as uncontrolled diabetes, severe hypertension, cardiovascular disease, or psychiatric disorders.
  • Diagnosed with chronic pain before surgery, or regular use of pain medications.
  • Opioid, alcohol addiction or dependence.
  • Pathological cesarean deliveries (placenta praevia, placental abruption, placenta accreta).
  • Multiple pregnancies (twins, triplets, etc.).
  • Post-operative complications (wound infection, hemorrhage, coagulation disorders, or loss of the child).
  • Severe postpartum urinary retention requiring urinary catheterization.
  • Refusing to participate.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
60 participants (actual)

Study arms

  • Experimental
    Real Acupressure + Standard Care

    Participants receive real acupressure at Hegu (LI4), Neiguan (PC6), and Sanyinjiao (SP6) points for 15 minutes daily over 3 consecutive days post-cesarean section, combined with standard modern medical care.

    Procedure: Acupressure · Behavioral: Standard care

  • Sham comparator
    Sham Acupressure + standard care

    Participants receive sham acupressure at non-acupoints for 15 minutes daily over 3 consecutive days post-cesarean section, combined with standard modern medical care.

    Procedure: Sham Acupressure · Behavioral: Standard care

Interventions

  • ProcedureAcupressure

    Manual massage and acupressure using techniques of rubbing (xoa) for 20-30 seconds, followed by pressing (an) for 5 seconds, kneading (day) for 5 seconds, and resting for 5 seconds, repeating for 2 minutes per point. A total of 15 minutes for 6 bilateral points (Hegu \[LI4\], Neiguan \[PC6\], Sanyinjiao \[SP6\]) will be performed once daily for 3 consecutive days. All procedures will be performed by a licensed traditional medicine physician following standardized protocols.

  • ProcedureSham Acupressure

    Sham acupressure using identical techniques (xoa, day, an), duration (3 days), and instructions at 3 bilateral non-therapeutic points: Sham Hegu (on the back of the hand, 1 thon from the midpoint between index and middle fingers), Sham Neiguan (inner forearm, 2 thon from wrist crease and 1.5 thon towards the radial side), and Sham Sanyinjiao (3 thon above the medial malleolus, then 1.5 thon posterior on the Achilles tendon). All procedures will be performed by a licensed traditional medicine physician.

  • BehavioralStandard care

    Standard post-operative modern pain management of the hospital: Post-op Day 1: Paracetamol 1g IV q6-8h ± Diclofenac 100mg rectally q12h; Post-op Day 2 onwards: Paracetamol 1g PO q8h ± Diclofenac 100mg rectally q12h or other NSAIDs as prescribed.

  • BehavioralStandard care

    Standard post-operative modern pain management of the hospital (identical to the experimental arm).

06

What researchers measure

Primary outcomes

  1. Change in pain score (Visual Analog Scale for Pain, VAS-P)

    Pain is assessed using Visual Analog Scale (VAS-P) ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst possible pain.

    Time frame: From baseline (T1, pre-intervention) to Day 3 (T2, post-intervention)

Secondary outcomes

  1. Change in anxiety score (Visual Analog Scale for Anxiety, VAS-A)

    Anxiety will be assessed using a 10cm Visual Analog Scale for Anxiety (VAS-A), where 0 indicates no anxiety and 10 indicates extreme anxiety.

    Time frame: From baseline (T1, pre-intervention) to Day 3 (T2, post-intervention)

  2. Change in state anxiety score (State-Trait Anxiety Inventory - State scale, STAI-Y1)

    State anxiety will be measured using the 20-item STAI-Y1 questionnaire (scores range from 20 to 80, with higher scores indicating higher anxiety).

    Time frame: From baseline (T1, pre-intervention) to Day 3 (T2, post-intervention)

  3. Incidence of adverse events related to the intervention

    All adverse events (e.g., pain at site, fatigue, bruising, internal bleeding, nerve injury) will be recorded throughout the study period.

    Time frame: From baseline (T1, pre-intervention) to Day 3 (T2, post-intervention)

07

Study locations

1 site
  • Tien Giang Obstetrics and Gynecology Hospital
    Mỹ Tho, Tien Giang, Vietnam
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Apr 2026 to primary completion in May 2026, 0 months.

Of 2,094 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's 0 months is below that.

Counting every sponsor, half of 2,107 studies reached it within 11 months; a quarter within 6 and three quarters within 23.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 1, 2026
First posted
Sep 4, 2026
StartActual
Apr 25, 2026
Primary completionActual
May 10, 2026
CompletionActual
May 10, 2026
Last update
Sep 10, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07805720
Responsible party
Truong Dieu Huong (Master Student, University of Medicine and Pharmacy at Ho Chi Minh City) — Principal investigator
First posted
Sep 4, 2026
Start date
Apr 25, 2026
Primary completion
May 10, 2026
Completion
May 10, 2026
Last update
Sep 10, 2026

Study contacts

Dieu Huong Truong
principal investigator · University of Medicine and Pharmacy at Ho Chi Minh City

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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