An interventional study of Menthol Chewing Gum in Postoperative Nausea and Vomiting, Bowel Functions and Postoperative Recovery, sponsored by Sennur Kula Şahin. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-01.
Sponsored by Sennur Kula Şahin · Not applicable, Interventional, and Supportive care
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Among 96 studies in Postoperative Nausea and Vomiting with a site in Turkey — 22 open to participants now, 23 under way, none of them phase 3. Postoperative Nausea and Vomiting · Turkey.
Among the 96 studies in Postoperative Nausea and Vomiting with a site in Turkey, this one is the 60th largest by enrollment of the 71 interventional ones that give a count, is one of 10 that started in 2024, is one of 55 with no phase, and was the 91st registered.
638 studies on the registry are indexed under Postoperative Nausea and Vomiting; 110 are open to participants now.
Browse Postoperative Nausea and Vomiting studies →22 of the 96 studies in Postoperative Nausea and Vomiting with a site in Turkey are open now. Recruiting first, the newest first:
Filiz Kaya · Sites in Turkey
Ages 18–65
Konya City Hospital · Sites in Turkey
Ages 18–45 · Women only
Ankara Etlik City Hospital · Sites in Turkey
Ages 18–65 · Women only
Nigde Omer Halisdemir University · Sites in Turkey
Ages 18–45 · Women only
Trabzon Kanuni Education and Research Hospital · Sites in Turkey
Ages 18–65 · Healthy volunteers
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 65 Postoperative Nausea and Vomiting studies recruiting now, 22 (34%) set no upper age limit and 37 (57%) stop at 75 or younger; 14 take children under 18; 11 take healthy volunteers.
This study: 18 Years to 60 Years · all sexes · healthy volunteers too.
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96 studies; the count open now beside each. This study's row is marked.
First in 2004; this study’s year is marked. 10 started in 2024.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 50 is below the median of 112 across 529 interventional studies indexed under Postoperative Nausea and Vomiting.
Median enrollment 90 across the 71 interventional studies, 100 across the 25 observational. Of the 61 that completed or were terminated, 3 (5%) have results posted.
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2 of 96 have an industry lead sponsor. The 10 most frequent:
Sennur Kula Şahin is the lead sponsor of 4 studies on the registry; none are open to participants now.
Sennur Kula Şahin has 1 study filed under Postoperative Nausea and Vomiting — fewer than ten, so there is no comparison to draw.
7 of the studies in Postoperative Nausea and Vomiting with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07440667Nigde Omer Halisdemir UniversityRestrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section | 2027-01-30 |
| NCT07539831Konya City HospitalEffects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery | 2027-03-03 |
| NCT07858058Ataturk UniversityThe Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty | 2027-03-15 |
| NCT07916077Ankara Etlik City HospitalPreoperative Gastric Volume and PONV in Pediatric Appendectomy Cases | 2027-04-15 |
| NCT07879274Bitlis Eren UniversityBinaural Beats and Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy | 2027-04-30 |
Add all 7 to your calendar (.ics) → With an account.
Among the 96 studies in Postoperative Nausea and Vomiting with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery. A total of 50 patients were randomly assigned to an intervention group (n=25) or a control group (n=25). Participants in the intervention group received menthol chewing gum in addition to standard postoperative care, while participants in the control group received standard postoperative care only. Nausea, bowel function, and postoperative recovery were assessed during the first three postoperative days.
Postoperative nausea and vomiting and delayed return of bowel function are common concerns following laparoscopic colorectal surgery and may affect postoperative recovery. Chewing gum is a non-pharmacological intervention that may stimulate gastrointestinal activity.
This randomized controlled trial evaluated the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery. Participants were randomly allocated to an intervention group or a control group.
Both groups received routine postoperative treatment and nursing care. In the intervention group, participants chewed menthol gum for 30 minutes and repeated the intervention three hours later. The same procedure was applied on the first, second, and third postoperative days. Participants in the control group received routine postoperative treatment and care without menthol chewing gum.
Postoperative nausea, bowel function, and recovery status were evaluated during the first three postoperative days. Postoperative recovery was assessed using the Surgical Recovery Status Scale, and nausea intensity was assessed using a Visual Analog Scale.
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Exclusion Criteria:
Menthol Chewing Gum Group
Behavioral: Menthol Chewing Gum
Control Group
Participants chewed menthol gum for 30 minutes, followed by a second 30-minute chewing session three hours later. This intervention was repeated on postoperative days 1, 2, and 3 in addition to standard postoperative care.
Postoperative Nausea and Vomiting Frequency
The frequency of postoperative nausea and vomiting was recorded for each participant during the first three postoperative days. Higher values indicate a greater frequency of nausea and vomiting.
Time frame: Postoperative days 1, 2, and 3
Postoperative Gas Passage Frequency
The frequency of defecation was recorded during the first three postoperative days as an indicator of postoperative bowel function.
Time frame: Postoperative days 1, 2, and 3
Postoperative Defecation Frequency
The frequency of defecation was recorded during the first three postoperative days as an indicator of postoperative bowel function.
Time frame: [Time Frame: Postoperative days 1, 2, and 3]
Postoperative Recovery Status
Postoperative recovery was assessed using the Surgical Recovery Status Scale. The scale consists of 25 items and five subscales: psychological symptoms, physical activities, general symptoms, bowel symptoms, and desire-related symptoms. Item scores are averaged to obtain the total score. Higher scores indicate greater difficulty in postoperative recovery, whereas lower scores indicate easier recovery.
Time frame: Postoperative days 1, 2, and 3
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2024 to primary completion in Apr 2024, 3 months.
Of 181 non-industry interventional studies with no phase under Postoperative Nausea and Vomiting, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 26. This study's 3 months is below that.
Counting every sponsor, half of 181 studies reached it within 13 months; a quarter within 5 and three quarters within 26.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Postoperative Nausea and Vomiting →
Sennur Kula Şahin