An observational study in Major Depressive Disorder (MDD), sponsored by Sohag University. Not yet recruiting. Open to participants aged 18 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-20.
Sponsored by Sohag University · Observational
This is a case control study including simple random cases of 90 persons, 45 of them have depressive disorders and the other 45 are healthy individuals,age group between 18-60 years old, cases will be recruited from outpatient psychiatric clinic in sohag university hospital, all cases will be exposed to psychological assessment and also laboratory assessment of kynurenine metabolites by using biokits
3,041 studies on the registry are indexed under Depressive Disorder, Major; 588 are open to participants now.
This study's planned enrollment of 90 is below the median of 131 across 400 observational studies indexed under Depressive Disorder, Major.
Browse Depressive Disorder, Major studies →Sohag University is the lead sponsor of 1,230 studies on the registry; 636 are open to participants now.
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Patients with age group between 18: 60 years old and all cases are drug free of at least 4 months
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Exclusion Criteria:
Psychological assessment of patients with depressive disorders
All cases will be subjected to psychological assessment by using structured clinical interview for DSM-V to assess major depressive disorder,bipolar and other depressivedisorders, Hamilton depression rating scale HAN-D to assess MDD, Hamilton anxiety inventory HAM-A to assess anxiety disorders, Montreal cognitive assessment to assess cognitive functions, Pittsburg sleep quality index to assess quality of sleep and detailed family history will be obtained to assess possibility of genetic factors in health relatives to patients with depressive disorders.
Time frame: From the enrollment of all cases till three months later
Detect abnormalities in kynurenine pathway in patients with depressive disorders
Blood samples will be collected from patients and healthy control cases in microbiology laboratory in Sohag university hospital; by using biokits for kynurenine to measure kynurenine level in nanomolar to low micromolar in liter, Add a tryptophan measure outcome to measure tryptophan level in micromol per liter Add a quinolinic acid measure outcome to measure quinolinic acid level in microgram per milliliter by ELISA
Time frame: From the time of enrollment till 3 months later
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This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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