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CompletedNCT07769112chx oilpullingUpdated Aug 17, 2026

Comparative Efficacy of Oil Pulling and Chlorhexidine on Plaque Induced Gingivitis

An interventional study of Chlorhexidine mouthwash (0.12%) and coconut oil pulling in Plaque Induced Gingivitis, sponsored by Liaquat College of Medicine and Dentistry. Completed at 1 site in Pakistan. Open to participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-08-17.

Sponsored by Liaquat College of Medicine and Dentistry · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 7 months after the study started (first participant enrolled Aug 2024, registered Apr 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
80
Allocation
Randomized
Ages
20 Years to 60 Years
Sex
All
01

Study summary

This randomized clinical trial aims to compare the efficacy of chlorhexidine and coconut oil in plaque-induced gingivitis patients. The study seeks to determine whether coconut oil pulling can provide comparable anti-plaque and anti-inflammatory effects to chlorhexidine mouthwash while producing fewer side effects. A total of 80 participants who diagnosed as plaque induced gingivitis will be randomly allocated into two equal groups (coconut and chlorhexidine). Clinical parameters, including Plaque Index and Gingival Index, will be assessed at baseline, day 7, day 14, and day 21 to evaluate changes in plaque and gingival inflammation following the interventions.

02

Conditions studied

  • Plaque Induced Gingivitis

Keywords

  • gingivitis, chlorhexidine, coconut oil, dental plaque , oral hygiene, periodontal diseases
03

In context

Gingivitis

631 studies on the registry are indexed under Gingivitis; 107 are open to participants now.

This study's enrollment of 80 is above the median of 66 across 507 interventional studies indexed under Gingivitis.

Browse Gingivitis studies →

Lead sponsor

Liaquat College of Medicine and Dentistry is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Individual aged between 22-60years.
  2. Individual who have retained 28 no of teeth in the mouth.
  3. Individuals who have diagnosed as plaque induced gingivitis along with mild to moderate gingival inflammation.

Exclusion criteria

Exclusion Criteria:

  1. Individual who have any systemic medical illness
  2. Multiple extractions, overhang restoration, wearing any appliance
  3. Periodontal problem with pocket depth more than 3mm
  4. Current or recent history of antibiotic consumption
  5. Non compliance that is unable to maintain their hygiene -
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
80 participants (actual)

Study arms

  • Experimental
    chlorhexidine mouthwash group

    Participants will use 0.12% chlorhexidine mouthwash twice daily for 21 days.

    Other: Chlorhexidine mouthwash (0.12%)

  • Experimental
    coconut oil pulling group

    Participants will rinse with coconut oil once daily for 10-15 minutes for 21 days.

    Other: coconut oil pulling

Interventions

  • OtherChlorhexidine mouthwash (0.12%)

    Participants will use 0.12% chlorhexidine mouthwash twice daily for 21 days.

  • Othercoconut oil pulling

    Participants will rinse with coconut oil once daily for 10-15 minutes for 21 days.

06

What researchers measure

Primary outcomes

  1. Reduction in Gingival Inflammation

    To assess the gingival inflammation using Gingival Index scores in participants receiving chlorhexidine mouthwash and coconut oil pulling therapy

    Time frame: Baseline, Day 7, Day 14, and Day 21

Secondary outcomes

  1. Reduction in Dental Plaque

    Evaluation of dental plaque accumulation using Plaque Index scores among study participants.

    Time frame: Baseline, Day 7, Day 14, and Day 21

07

Study locations

1 site
  • Dr. Nida Tariq
    Karachi, Sindh 75330, Pakistan
08

References and documents

Individual participant data

Plan to share: No — Protecting participant confidentiality in a small sample size. No infrastructure for secure data storage and distribution onsent obtained does not cover future data sharing.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07769112
Lead sponsor
Liaquat College of Medicine and Dentistry
Responsible party
Sponsor
First posted
Aug 17, 2026
Start date
Aug 12, 2024
Primary completion
Feb 23, 2025
Completion
Jul 12, 2025
Last update
Aug 17, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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