An interventional study of Abdominal massage and chewing egzersize in Post-Colonoscopy Nausea and Vomiting and Abdominal Pain, sponsored by Sakarya University. Completed at 2 sites in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-12.
Sponsored by Sakarya University · Not applicable, Interventional, and Supportive care
Among 61 studies in Vomiting with a site in Turkey — 14 open to participants now, 16 under way, none of them phase 3. Vomiting · Turkey.
Among the 61 studies in Vomiting with a site in Turkey, this one is the 28th largest by enrollment of the 54 interventional ones that give a count, is one of 12 that started in 2025, is one of 46 with no phase, and was the 56th registered.
793 studies on the registry are indexed under Vomiting; 99 are open to participants now.
Browse Vomiting studies →14 of the 61 studies in Vomiting with a site in Turkey are open now. Recruiting first, the newest first:
Sanliurfa Education and Research Hospital · Sites in Turkey
Ages 18+ · Women only
Aydin Adnan Menderes University · Sites in Turkey
Ages 6 mo–5 yrs
Nermin Ocaktan · Sites in Turkey
Ages 18+
Eli Lilly and Company · Sites in Turkey, United States, Australia and 7 more countries
Ages 18+
Helsinn Healthcare SA · Sites in Turkey, Greece, Poland and 1 more country
Ages 0 mo–18 yrs
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 56 Vomiting studies recruiting now, 26 (46%) set no upper age limit and 24 (43%) stop at 75 or younger; 10 take children under 18; 17 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
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61 studies; the count open now beside each. This study's row is marked.
First in 2004; this study’s year is marked. 12 started in 2025.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 60 is below the median of 103 across 673 interventional studies indexed under Vomiting.
Median enrollment 64 across the 54 interventional studies, 100 across the 7 observational. Of the 40 that completed or were terminated, 0 (0%) have results posted.
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3 of 61 have an industry lead sponsor. The 10 most frequent:
Sakarya University is the lead sponsor of 190 studies on the registry; 53 are open to participants now.
Sakarya University has 3 studies filed under Vomiting — fewer than ten, so there is no comparison to draw.
5 of the studies in Vomiting with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07169851Eli Lilly and CompanyA Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer | 2026-12 |
| NCT07861737Kayseri City HospitalGranisetron Use, Blood Pressure, and Nausea and Vomiting During Cesarean Delivery Under Spinal Anesthesia | 2026-12-15 |
| NCT07610382Aydin Adnan Menderes UniversityBalanced Crystalloid vs Normal Saline in Pediatric Acute Gastroenteritis | 2027-01 |
| NCT07740577Sanliurfa Education and Research HospitalRoutine Antiemetic Prophylaxis for Nonfasted Parturients Undergoing Cesarean Sections Under Spinal Anesthesia | 2027-01-01 |
| NCT06904235Helsinn Healthcare SAStudy With IV NEPA (Fosnetupitant/Palonosetron) for the Prevention of Chemotherapy-induced Nausea and Vomiting in Paediatric Cancer Patients Undergoing Highly Emetogenic Chemotherapy (HEC) | 2027-10 |
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Among the 61 studies in Vomiting with a site in Turkey, from their registry updates:
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This study is planned with a randomized controlled experimental design to determine the effects of chewing exercises during the pre-colonoscopy preparation process and abdominal massage applied after the procedure on abdominal pain and nausea symptoms.
The research population consists of patients applying to the Surgical Endoscopy Unit of a Training and Research Hospital for a colonoscopy. The sample will consist of individuals who agree to participate and meet the inclusion criteria. The study will be composed of two different groups: an experimental group and a control group. Group assignment will be determined by a randomized lottery method conducted by an independent observer.
Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. The educational information provided to the chewing exercise group will be based on the "Oral-Motor Exercises Brochure" published by the Ministry of Health. Participants will be asked to perform the specified exercises at least 2-3 times for a duration of 25-30 minutes the day before. Chewing is a recommended practice for generating saliva, relaxing gastric juice, and stimulating intestinal movements; thus, it is planned to alleviate the individual's post-colonoscopy gastrointestinal problems.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
No additional interventions were performed on the participants in this group following the colonoscopy. They received routine care.
Arm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure.
Other: Abdominal massage and chewing egzersize
Arm Description: Patients in the experimental group will be instructed to perform chewing movements a day before the procedure during bowel preparation, as chewing is known to increase saliva flow rate via the oropharyngeal mechanism. Abdominal massage is a non-invasive, easy-to-apply method with no side effects, performed by nurses to reduce abdominal distension after colonoscopy. The researcher will apply it for 3-5 minutes when the patient is taken to the post-op recovery room after the procedure.
Blood pressure measument
To measure blood pressure, the systolic and diastolic values are combined and expressed in mm/Hg.
Time frame: 4 months
Oxygen saturation
Oxygen saturation will be expressed as a percentage.
Time frame: 4 months
Pulse
The pulse rate will be measured and recorded as the number of heartbeats per minute.
Time frame: 4 months
Pain assessment
Pain levels will be assessed on a scale from 0 to 10, where "0" indicates no pain and "10" indicates very severe pain.
Time frame: 4 months
Presence of Nausea Before and After Colonoscopy (yes/no)
Nausea will be assessed based on participant self-report and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of nausea will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Time frame: 4 months
Presence of Vomiting Before and After Colonoscopy (yes/no)
Vomiting will be assessed based on participant self-report and/or direct observation and recorded as a dichotomous outcome (present/absent) using the study data collection form. The presence or absence of vomiting will be evaluated at three time points: before colonoscopy, after colonoscopy, and before discharge.
Time frame: 4 months
Plan to share: No — Once the study is completed, the data may be shared if requested by researchers.
Ran from Jun 2025 to primary completion in Jun 2025, 0 months.
Of 131 non-industry interventional studies with no phase under Vomiting, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 29. This study's 0 months is below that.
Counting every sponsor, half of 134 studies reached it within 13 months; a quarter within 6 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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