An interventional study of IN theatre and ON unit in Necrotising Enterocolitis Neonatal, sponsored by Guy's and St Thomas' NHS Foundation Trust. Not yet recruiting. Per ClinicalTrials.gov, last updated 2026-08-10.
Sponsored by Guy's and St Thomas' NHS Foundation Trust · Not applicable, Interventional, and Treatment
This is a pilot randomised trial allocating neonates requiring emergency laparotomy to surgery either on the neonatal unit or in the operating theatre.
Outcome will include physiological markers of instability, wound infection, death and others. There will also be a concurrent qualitative workstream exploring the impact of different practices on the wider clinical environment.
228 studies on the registry are indexed under Enterocolitis, Necrotizing; 44 are open to participants now.
This study's planned enrollment of 15 is below the median of 103 across 127 interventional studies indexed under Enterocolitis, Necrotizing.
Browse Enterocolitis, Necrotizing studies →Guy's and St Thomas' NHS Foundation Trust is the lead sponsor of 295 studies on the registry; 80 are open to participants now.
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Exclusion Criteria:
Babies will have their surgery performed on the neonatal unit without transfer to a theatre
Procedure: ON unit
Babies will be transferred to the operating theatre for surgery
Procedure: IN theatre
Surgery will take place in the operating theatre
Surgery will take place on the neonatal unit
Death
Survival to discharge
Time frame: Until discharge from hospital from primary episode, around 3-4 months
Physiological parameters
As a pilot study, many different physiological parameters as markers of clinical stability will be collected and assessed for their suitability in a definitive study
Time frame: During the course of the admission, including the immediate peri-operative period and subsequent recovery phase. Four weeks from surgery
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Guy's and St Thomas' NHS Foundation Trust →