An observational study in Class II Malocclusion, Dentofacial Deformities and Retrognathia, sponsored by Istanbul Medipol University Hospital. Active, not recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-24.
Sponsored by Istanbul Medipol University Hospital · Observational
This retrospective cohort study aims to compare the effects of Mini Wing and Box genioplasty performed in conjunction with bimaxillary orthognathic surgery on upper airway area and soft tissue profile in adult patients with skeletal Class II dentofacial deformity. Preoperative and postoperative radiographic measurements will be evaluated to determine changes in upper airway area, mentolabial angle, and submental angle. The study also aims to assess whether either genioplasty technique provides superior postoperative functional and esthetic outcomes.
Skeletal Class II dentofacial deformity is commonly treated with bimaxillary orthognathic surgery combined with genioplasty to improve facial harmony and functional outcomes. Among the available genioplasty techniques, Mini Wing and Box genioplasty differ in their osteotomy design and the direction of chin advancement, which may influence postoperative soft tissue profile and upper airway morphology.
This retrospective cohort study includes adult patients who underwent bimaxillary orthognathic surgery with either Mini Wing or Box genioplasty at Istanbul Medipol University between 2019 and 2025. Patients meeting the predefined inclusion and exclusion criteria will be identified through hospital records. Preoperative and postoperative cone-beam computed tomography (CBCT) images will be analyzed to evaluate changes in upper airway area, mentolabial angle, and submental angle.
Demographic characteristics and baseline measurements will be compared between groups to ensure similarity before surgery. Postoperative changes within each group and differences between the two surgical techniques will be statistically analyzed. The findings are expected to provide evidence regarding the effects of Mini Wing and Box genioplasty on upper airway dimensions and soft tissue profile, thereby supporting surgical planning and technique selection in patients with skeletal Class II deformity.
40 studies on the registry are indexed under Dentofacial Deformities; 16 are open to participants now.
This study's enrollment of 40 is below the median of 45 across 15 observational studies indexed under Dentofacial Deformities.
Browse Dentofacial Deformities studies →Istanbul Medipol University Hospital is the lead sponsor of 366 studies on the registry; 46 are open to participants now.
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Adult patients with skeletal Class II dentofacial deformity who underwent bimaxillary orthognathic surgery combined with Mini Wing or Box genioplasty at Istanbul Medipol University between 2019 and 2025.
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Exclusion Criteria:
Patients with skeletal Class II dentofacial deformity who underwent bimaxillary orthognathic surgery combined with Mini Wing genioplasty.
Procedure: Mini Wing Genioplasty
Patients with skeletal Class II dentofacial deformity who underwent bimaxillary orthognathic surgery combined with Box genioplasty.
Procedure: Box Genioplasty
Mini Wing genioplasty performed in conjunction with bimaxillary orthognathic surgery for correction of skeletal Class II dentofacial deformity.
Box genioplasty performed in conjunction with bimaxillary orthognathic surgery for correction of skeletal Class II dentofacial deformity.
Change in Upper Airway Area
Change in upper airway area measured on cone-beam computed tomography (CBCT) images obtained before surgery and 6 months after surgery.
Time frame: Preoperative and 6 months after surgery
Change in Mentolabial Angle
Change in the mentolabial angle measured on CBCT images before surgery and 6 months after surgery.
Time frame: Preoperative and 6 months after surgery
Change in Submental Angle
Change in the submental angle measured on CBCT images before surgery and 6 months after surgery.
Time frame: Preoperative and 6 months after surgery
Plan to share: No — Individual participant data will not be shared because the study is retrospective and contains confidential patient information. Data sharing is restricted to protect participant privacy and is subject to institutional and ethical regulations.
No publications or documents are linked to this record.
Ran from Mar 2019 to primary completion in Jul 2026, 88 months.
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This study is active, not recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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