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CompletedNCT07702084Updated Oct 7, 2026

Effect of Regional Anesthesia Techniques on Perioperative Blood Loss in Femoral Neck Fracture Surgery

An observational study in Femoral Neck Fractures, Blood Loss, Surgical and Postoperative Pain, sponsored by Bursa Yuksek Ihtisas Training and Research Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-10-07.

Sponsored by Bursa Yuksek Ihtisas Training and Research Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
150
Ages
18 Years to 100 Years
Sex
All
01

Study summary

This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery. Patients who received tranexamic acid were grouped by anesthesia method (lumbar plexus block, spinal anesthesia, or general anesthesia). The primary outcomes were intraoperative blood loss and the change in hemoglobin between the preoperative and postoperative periods. Secondary outcomes were postoperative pain (VAS) and total analgesic consumption during the first 24 hours.

02

Conditions studied

  • Femoral Neck Fractures
  • Blood Loss, Surgical
  • Postoperative Pain

Keywords

  • Regional anesthesia
  • Nerve block
  • Lumbar plexus block
  • Spinal anesthesia
  • Tranexamic acid
  • Hip fracture surgery
03

In context

Femoral Neck Fractures

204 studies on the registry are indexed under Femoral Neck Fractures; 41 are open to participants now.

This study's enrollment of 150 is above the median of 134 across 59 observational studies indexed under Femoral Neck Fractures.

Browse Femoral Neck Fractures studies →

Lead sponsor

Bursa Yuksek Ihtisas Training and Research Hospital is the lead sponsor of 46 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients aged 18-100 years who underwent femoral neck fracture surgery and received tranexamic acid, identified by retrospective chart review

Inclusion criteria

  • Aged 18 to 100 years
  • ASA physical status I-IV
  • Underwent femoral neck fracture surgery
  • Received tranexamic acid

Exclusion criteria

Exclusion Criteria:

  • Allergy to local anesthetics
  • Bleeding diathesis or coagulation disorder
  • Mental disorder
  • Allergy to the drugs used
  • History of cerebrovascular disease
  • Body mass index greater than 30 kg/m2
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
150 participants (actual)
Patient registry
No

Groups and cohorts

  • Group L - Lumbar plexus block

    Patients who received lumbar plexus block plus tranexamic acid.

  • Group S - Spinal anesthesia

    Patients who received spinal anesthesia combined with tranexamic acid.

  • Group G - General anesthesia

    Patients who received general anesthesia combined with tranexamic acid.

06

What researchers measure

Primary outcomes

  1. Intraoperative blood loss

    Intraoperative blood loss estimated from the volume in the aspirator container and the blood absorbed in surgical sponges

    Time frame: Intraoperative (during surgery)

  2. Change in hemoglobin level

    Difference between preoperative and postoperative hemoglobin concentration (g/dL)

    Time frame: Preoperative and within 24 hours postoperatively

Secondary outcomes

  1. Postoperative pain score (VAS)

    Postoperative pain assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst pain); higher scores indicate worse pain.

    Time frame: 2, 6, 12 and 24 hours postoperatively

  2. Total analgesic consumption

    Total amount of analgesic consumed in the first 24 postoperative hours

    Time frame: First 24 hours postoperatively

07

Study locations

1 site
  • Bursa Yüksek Ihtisas Training and Research Hospital
    Bursa, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared.

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Minor edits
Nothing that changes what the study is or who can join. Edited: verification date and secondary outcomes
1 update, last Oct 7, 2026
Show all 1 update
  1. Oct 7, 2026
    Minor edits only
    + 2 other changes: verification date and secondary outcomes

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07702084
Lead sponsor
Bursa Yuksek Ihtisas Training and Research Hospital
Responsible party
Cihan Sedat Aytünür (Associate Professor of Anesthesiology and Reanimation, Bursa Yuksek Ihtisas Training and Research Hospital) — Principal investigator
First posted
Jul 14, 2026
Start date
Jul 30, 2020
Primary completion
Jun 30, 2022
Completion
Jun 30, 2022
Last update
Oct 7, 2026

Study contacts

Korgün Ökmen, MD
principal investigator · University of Health Sciences, Bursa Yüksek Ihtisas Training and Research Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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