An interventional study of SHOFU Hard blocks and BRILLIANT Crios in Wear, Occlusal, sponsored by Cairo University. Not yet recruiting. Open to participants aged 22 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-07-07.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus Resin-based Composite (BRILLIANT Crios) overlays, utilizing a digital subtraction methodology (Intraoral Scanner and Geometrical Subtraction Software) in endodontically treated molar teeth.
The rationale for this 24-month RCT is driven by the need for high-level, evidence-based data to guide clinical material selection for compromised teeth. This trial is designed to directly compare two materials specifically engineered to be stress-absorbing in the oral environment. The primary intervention, the SHOFU Restorative System (Hard blocks), is a Hybrid Ceramic engineered to combine the durability of ceramics with the elasticity of polymers. Its reduced hardness and dentin-like modulus allow for rapid machining and are associated with reduced antagonist abrasion compared to conventional ceramics. The second material, serving as the comparator, is the Coltène Restorative System (BRILLIANT Crios), which is a reinforced nano-hybrid composite characterized by an elastic modulus comparable to dentin, designed for optimal shock absorption and confirmed to be gentle on antagonist teeth.
Focusing the study on endodontically treated molars addresses a highly prevalent clinical scenario where maximizing the longevity of the restoration and the remaining tooth structure is paramount. The use of a full-cusp-coverage overlay design represents the maximum conservation approach for these compromised teeth while ensuring that the selected restorative materials do not exert harmful effects on opposing dentition.
14 studies on the registry are indexed under Tooth Attrition; 5 are open to participants now.
This study's planned enrollment of 24 is close to the median of 26 across 11 interventional studies indexed under Tooth Attrition.
Browse Tooth Attrition studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
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Exclusion Criteria:
* Presence of bruxism.
CAD/CAM Hybrid Ceramic, Overlay restored using the SHOFU cementation system.
Procedure: SHOFU Hard blocks
Resin-based Composite, Overlay restored using the Coltène cementation system.
Procedure: BRILLIANT Crios
CAD/CAM Hybrid Ceramic, Overlay restored using the SHOFU cementation system.
Resin-based Composite, Overlay restored using the Coltène cementation system.
Annual wear rate
Digital Scanner +Geometrical Subtraction Software
Time frame: 24 months
Functional properties, Biological properties and Esthetic properties
FDI Criteria
Time frame: 24 months
No study locations are listed for this record.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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