An interventional study of Plasma vitamin C assessment in Osteoporosis, Vitamin C Deficiency and Vertebral Fractures, sponsored by Centre Hospitalier Universitaire de Nice. Not yet recruiting at 1 site in France. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-06-22.
Sponsored by Centre Hospitalier Universitaire de Nice · Not applicable, Interventional, and Diagnostic
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the Rheumatology
. Next, the collection of planned clinical and paraclinical data:
1,601 studies on the registry are indexed under Osteoporosis; 209 are open to participants now.
This study's planned enrollment of 40 is below the median of 88 across 1,084 interventional studies indexed under Osteoporosis.
Browse Osteoporosis studies →Centre Hospitalier Universitaire de Nice is the lead sponsor of 723 studies on the registry; 176 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Postmenopausal
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient with osteoporosis and recent clincal vertebral fracture.
Diagnostic Test: Plasma vitamin C assessment
Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient with osteoporosis without vertebral fracture.
Diagnostic Test: Plasma vitamin C assessment
Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient of the study
Plasma vitamin C concentration
Comparison of plasma vitamin C concentration (ascorbemia, µmol/L) between patients with osteoporotic vertebral fractures and patients with osteoporosis without vertebral fracture.
Time frame: day 1
Association between plasma vitamin C level and number of vertebral fractures
Assessment of the relationship between plasma vitamin C concentration and the number of osteoporotic vertebral fractures
Time frame: day 1
Association between plasma vitamin C level and lumbar bone mineral density
Assessment of the relationship between plasma vitamin C concentration and lumbar spine bone mineral density measured by DXA.
Time frame: day 1
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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