An interventional study of IPT-A-SCI in Suicidal Ideation and Suicidal Behavior, sponsored by Tel Aviv University. Not yet recruiting at 1 site in Israel. Open to participants aged 8 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-06-11.
Sponsored by Tel Aviv University · Not applicable, Interventional, and Treatment
Among 11 studies in Suicidal Ideation with a site in Israel — 5 open to participants now, 5 under way, none of them phase 3. Suicidal Ideation · Israel.
Among the 11 studies in Suicidal Ideation with a site in Israel, this one is the 3rd largest by planned enrollment of the 10 interventional ones, is one of 4 that started in 2026, is one of 6 with no phase, and was the 9th registered.
569 studies on the registry are indexed under Suicidal Ideation; 203 are open to participants now.
This study's planned enrollment of 120 is above the median of 80 across 469 interventional studies indexed under Suicidal Ideation.
Browse Suicidal Ideation studies →5 of the 11 studies in Suicidal Ideation with a site in Israel are open now, in 1 country. Each count lists the studies.
Of the 134 Suicidal Ideation studies recruiting now, 51 (38%) set no upper age limit and 79 (59%) stop at 75 or younger; 54 take children under 18; 32 take healthy volunteers.
This study: 8 Years to 18 Years · all sexes · no healthy volunteers.
The full table on the hub →11 studies; the count open now beside each. This study's row is marked.
First in 2007; this study’s year is marked. 4 started in 2026.
Median enrollment 81 across the 10 interventional studies, 19 across the 1 observational. Of the 3 that completed or were terminated, 0 (0%) have results posted.
None of the 11 has an industry lead sponsor. The 10 most frequent:
Tel Aviv University is the lead sponsor of 100 studies on the registry; 26 are open to participants now.
Tel Aviv University has 1 study filed under Suicidal Ideation — fewer than ten, so there is no comparison to draw.
1 of the studies in Suicidal Ideation with a site in Israel that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07913425University of HaifaExamining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents | 2027-06-30 |
Among the 11 studies in Suicidal Ideation with a site in Israel, from their registry updates:
The goal of this clinical trial is to learn if the Ultra-Brief Interpersonal Psychotherapy for Adolescents with Suicidal Ideation (IPT-A-SCI) works to reduce suicidal thoughts and behaviors in children and adolescents. The study will also examine whether treatment effects continue after treatment ends and whether some participants benefit more from the intervention than others. The main questions it aims to answer are:
Does IPT-A-SCI reduce suicidal thoughts and behaviors in children and adolescents? Do the effects of IPT-A-SCI continue three months after treatment ends? Do some children and adolescents benefit more from IPT-A-SCI than others?
Participants will:
Receive IPT-A-SCI treatment consisting of five weekly sessions Complete questionnaires before treatment, during treatment, at the end of treatment, and three months after treatment ends Have their parents complete questionnaires at the same time points
IPT-A-SCI (Ultra-Brief Crisis Interpersonal Psychotherapy for Adolescents with Suicidal Ideation) is a manualized five-session crisis intervention based on Interpersonal Psychotherapy (IPT) principles.
IPT-A-SCI is designed for children and adolescents aged 8-18 presenting with suicidal ideation or behavior. The intervention combines IPT principles with the Safety Planning Intervention and includes a three-month post-intervention contact protocol.
This is a single-group, pre-post interventional study with repeated measures collected at four time points. All participants will receive the IPT-A-SCI intervention. There is no control or comparison group in this study, as the research focuses on within-person mechanisms of change and moderators of treatment response rather than between-group comparisons.
Participants will be recruited from the Child and Adolescent Clinic at Geha Mental Health Center through emergency room referrals, outpatient providers, and treating therapists at the clinic. Initial evaluation and suicide risk assessment will be conducted by experienced clinical staff according to established clinical guidelines for suicide risk assessment in adolescents.
Up to 120 participants will be enrolled over an estimated two-year recruitment period.
During the three months following treatment, participants will receive three personalized emails at 2 weeks, 1 month, and 2 months post-treatment. A follow-up session will take place three months after treatment completion. Psychiatric or psychosocial treatment may continue as usual during IPT-A-SCI.
Statistical Analysis Plan:
Three complementary analytic frameworks will be used:
Latent Change Score (LCS) modeling will be used to assess changes in suicidal ideation and related clinical outcomes from baseline to post-treatment and follow-up. Associations between changes in proposed mechanisms and changes in suicidality will be examined to identify factors that may contribute to treatment effectiveness.
Linear Mixed-Effects Models (LMMs) will be used to examine whether treatment effectiveness varies according to baseline participant characteristics, including initial suicide risk severity and other demographic and clinical variables. These analyses will identify moderators of treatment response and determine which participants derive the greatest benefit from the intervention.
Missing data will be handled in accordance with established best practices for longitudinal clinical research. The analytic approaches described above accommodate missing data under missing-at-random assumptions.
Data Collection and Management:
Safety Monitoring and Ethical Considerations:
This study focuses on children and adolescents at risk for suicide. The Child and Adolescent Clinic at Geha Mental Health Center is located on the grounds of a psychiatric hospital with a 24/7 emergency room. Participants presenting with acute suicidal crisis during the study may be referred immediately for emergency psychiatric evaluation.
All treating clinicians are trained in suicide risk assessment and management. Adverse events, including worsening suicidal ideation or behavior, will be documented and reported in accordance with Helsinki Committee requirements and Good Clinical Practice guidelines.
No formal Data Safety Monitoring Board (DSMB) is in place for this study given its single-site naturalistic design. Clinical oversight will be provided through routine supervision and case conferencing.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will receive the IPT-A-SCI intervention consisting of five weekly sessions of ultra-brief interpersonal psychotherapy combined with safety planning for suicidal ideation and behavior.
Behavioral: IPT-A-SCI
Manualized ultra-brief interpersonal psychotherapy intervention combined with safety planning for children and adolescents with suicidal ideation or behavior.
Change in Severity of Suicidal Ideation
Change in severity of suicidal ideation and behavior assessed using the Columbia-Suicide Severity Rating Scale (C-SSRS). The C-SSRS assesses the severity of suicidal ideation and the occurrence of suicidal behaviors. The suicidal ideation severity score ranges from 1 to 5, with higher scores indicating greater severity of suicidal ideation.
Time frame: Baseline to 3-month follow-up
Change in Intensity of Suicidal Ideation
Change in intensity of suicidal ideation assessed using the Columbia-Suicide Severity Rating Scale (C-SSRS) ideation intensity scale. The C-SSRS assesses the intensity of the most severe suicidal ideation endorsed by evaluating five dimensions: frequency, duration, controllability, deterrents, and reasons for ideation. Total scores range from 0 to 25, with a score of 0 assigned when no suicidal ideation is endorsed and scores from 2 to 25 indicating increasing intensity of suicidal ideation. Higher scores indicate more intense suicidal ideation and a worse outcome.
Time frame: Baseline to 3-month follow-up
Change in Depressive Symptoms
Change in depressive symptoms assessed using the Short Mood and Feelings Questionnaire (SMFQ). Scores range from 0 to 26, with higher scores indicating greater depressive symptom severity and a worse outcome.
Time frame: Baseline to 3-month follow-up
Change in Perceived Social Support
Change in perceived social support assessed using the Multidimensional Scale of Perceived Social Support (MSPSS). Scores range from 12 to 84, with higher scores indicating greater perceived social support and a better outcome.
Time frame: Baseline to 3-month follow-up
Change in Emotional Processing (Alexithymia)
Change in emotional processing and alexithymia assessed using the Toronto Alexithymia Scale (TAS-20). Scores range from 20 to 100, with higher scores indicating greater difficulty identifying and describing emotions (greater alexithymia) and a worse outcome.
Time frame: Baseline to 3-month follow-up
Change in Hope
Change in hope assessed using the Children's Hope Scale (CHS). Scores range from 6 to 36, with higher scores indicating greater hopefulness and a better outcome.
Time frame: Baseline to 3-month follow-up
Change in Family Conflict and Interpersonal Stress
Change in family conflict and interpersonal stress assessed using the Family Environment Scale (FES) conflict subscale. Scores range from 0 to 9, with higher scores indicating greater family conflict and a worse outcome.
Time frame: Baseline to 3-month follow-up
Change in Irritability and Emotional Dysregulation
Change in irritability and emotional dysregulation assessed using the parent-report TIDES-13 questionnaire. Total scores range from 13 to 91, with higher scores indicating greater irritability and emotional dysregulation and a worse outcome.
Time frame: Baseline to 3-month follow-up
Change in Interpersonal and Social Functioning
Change in interpersonal and social functioning assessed using EFORTS social routine measures. Scores range from 0 to 5. with higher scores indicating better social routine functioning and executive functioning in daily activities and therefore a better outcome.
Time frame: Baseline to 3-month follow-up
Behavioral and Emotional Problems at Baseline
Behavioral and emotional problems assessed using the parent-report Child Behavior Checklist (CBCL). This measure will be used for descriptive and covariate analyses. Raw scores vary according to age and sex and are converted to standardized T-scores. Higher T-scores indicate greater emotional and behavioral problems and a worse outcome.
Time frame: Baseline only
Plan to share: Undecided
Start is estimated for Jun 2026; primary completion for Jun 2028, 24 months later.
Of 281 non-industry interventional studies with no phase under Suicidal Ideation, half reached primary completion within 30 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 54. This study's planned 24 months is below that.
Counting every sponsor, half of 290 studies reached it within 29 months; a quarter within 13 and three quarters within 53.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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