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Not yet recruitingNCT07626372B-FORCE RCTUpdated Jun 4, 2026

Bite Force and Occlusal Force Distribution Following Root Canal Treatment.

An observational study in Endodontically Treated Teeth, sponsored by Chulalongkorn University. Not yet recruiting at 1 site in Thailand. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-04.

Sponsored by Chulalongkorn University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
70
Ages
20 Years to 60 Years
Sex
All
01

Study summary

Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the treated tooth. Therefore, this study aims to further explore changes and possible correlation in maximum bite force (MBF), occlusal force distribution and patients' subjective perception of chewing function of endodontically treated teeth after non-surgical root canal treatment, subsequent restoration, and during long-term follow-up, along with comparing to contralateral vital teeth.

Methods: Patients aged 20-60 years who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University, with the following teeth indicated for endodontic treatment. Measurements of maximum bite force (MBF) of ETT and contralateral vital teeth, relative occlusal force (ROF), and questionnaire responses, are performed at the following time points: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Differences in MBF and ROF over time points within subjects and differences in MBF and ROF between ETT and their contralateral vital teeth were statistically analyzed.

02

Conditions studied

  • Endodontically Treated Teeth

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Keywords

  • Bite force
  • occlusal force distribution
  • Endodontically treated teeth
  • Chewing side preference
  • Endodontic restoration
  • Prospective study
03

In context

Tooth, Nonvital

111 studies on the registry are indexed under Tooth, Nonvital; 18 are open to participants now.

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Lead sponsor

Chulalongkorn University is the lead sponsor of 322 studies on the registry; 66 are open to participants now.

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04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Premolars or molars diagnosed with pulp necrosis or previously initiate therapy with normal apical tissues, asymptomatic apical periodontitis, or chronic apical abscess without full coverage restoration.
  • Adequate remaining tooth structure for cuspal coverage restoration.
  • Presence of adjacent teeth and functional opposing natural teeth.
  • No analgesics drug effect at the time of investigation or not have taken analgesics 6 hours ago.

Exclusion criteria

Exclusion Criteria:

  • Patients undergoing other dental treatments during the study period that may interfere with occlusion or bite force distribution, such as orthodontic treatment, jaw surgery, or full mouth restoration.
  • Received treatments that cause weakness of the jaw and facial muscles, such as botox injections.
  • History or symptoms of temporomandibular disorders (TMD)
  • Periodontal disease with second- or third-degree mobility
  • Teeth presenting crack lines extending into the pulp chamber floor or root canal orifices.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
70 participants (estimated)
Target follow-up
4 Years
Patient registry
Yes

Groups and cohorts

  • Endodontic patient

    Patients aged 20-60 years undergoing non-surgical root canal treatment and subsequent restoration at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University, with prospective assessment of bite force and occlusal force distribution over time.

06

What researchers measure

Primary outcomes

  1. Maximum bite force

    Maximum bite force of the endodontically treated tooth and its contralateral tooth in each patient will be measured using the FlexiForce ELF System and FlexiForce B201 sensor.

    Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

  2. Relative occlusal force

    Relative Occlusal Force are measured with the T-Scan III system. A device will be inserted into the mouth of the patients, and they are instructed to bite firmly three times at the maximum cusp intersection position.

    Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Secondary outcomes

  1. Patients' subjective perception of chewing function

    A questionnaire will be used to assess patients' subjective perceptions of chewing function, including preferred chewing side, frequency of hard food consumption, and parafunctional habits such as bruxism and clenching.

    Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

07

Study locations

1 site
  • Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn university
    Bangkok, 10330, Thailand
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 4, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07626372
Responsible party
Thanomsuk Jearanaiphaisarn (Associate Professor, Department of Operative Dentistry, Chulalongkorn University) — Principal investigator
First posted
Jun 4, 2026
Start date
Jun 8, 2026 (estimated)
Primary completion
Oct 31, 2027 (estimated)
Completion
Oct 31, 2030 (estimated)
Last update
Jun 4, 2026

Study contacts

Thanomsuk Jearanaiphaisarn
Contact
thanomsuk.j@chula.ac.th
6622188795

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.

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