An interventional study of Gac Fruit Oil Capsules in Sleep Disturbance and Visual Health, sponsored by Yuanpei University of Medical Technology. Completed at 1 site in Taiwan. Open to participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-03.
Sponsored by Yuanpei University of Medical Technology · Not applicable, Interventional, and Supportive care
This study evaluated the effects of gac fruit oil supplementation on visual health, sleep quality, depressive symptoms, cognitive function, and brain imaging parameters in adults with sleep disturbance. Participants aged 40 to 65 years were recruited and received gac fruit oil capsules for 30 days. The supplementation protocol consisted of two capsules in the morning and two capsules in the evening each day. Assessments were performed before and after the intervention, including macular pigment measurement, ocular surface disease evaluation, tear film analysis, contrast sensitivity testing, accommodative microfluctuation analysis, optical coherence tomography, the Pittsburgh Sleep Quality Index, a depression scale, the Mini-Mental State Examination, and brain magnetic resonance imaging. The study aimed to explore whether 30 days of gac fruit oil supplementation was associated with changes in visual function, sleep quality, mood-related measures, cognitive function, and brain imaging findings.
757 studies on the registry are indexed under Parasomnias; 190 are open to participants now.
This study's enrollment of 50 is below the median of 66 across 570 interventional studies indexed under Parasomnias.
Browse Parasomnias studies →Yuanpei University of Medical Technology is the lead sponsor of 2 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants received gac fruit oil capsules for 30 days. The supplementation protocol consisted of two capsules in the morning and two capsules in the evening each day.
Dietary Supplement: Gac Fruit Oil Capsules
Participants took gac fruit oil capsules orally for 30 days. The supplementation protocol consisted of two capsules in the morning and two capsules in the evening each day, for a total of four capsules per day.
Also known as: Momordica cochinchinensis Oil Capsules
Change in Sleep Quality
Sleep quality was assessed using the Pittsburgh Sleep Quality Index before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Depressive Symptoms
Depressive symptoms were assessed using a depression scale before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Macular Pigment Level
Macular pigment level was assessed using a macular pigment screener before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Ocular Surface Disease Symptoms
Ocular surface disease symptoms were assessed using the Ocular Surface Disease Index before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Tear Film Parameters
Tear film parameters were assessed using a non-contact ocular surface analyzer before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Contrast Sensitivity
Contrast sensitivity was assessed using the CVS-1000 contrast sensitivity test before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Accommodative Microfluctuation
Accommodative microfluctuation was assessed using an accommodative microfluctuation analyzer before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Retinal Structure
Retinal structure was assessed using optical coherence tomography before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Cognitive Function
Cognitive function was assessed using the Mini-Mental State Examination before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Change in Brain Magnetic Resonance Imaging Parameters
Brain magnetic resonance imaging parameters were assessed before and after 30 days of gac fruit oil supplementation.
Time frame: Baseline and 30 days
Plan to share: No — Individual participant data will not be shared because the study data include health-related questionnaire responses, ophthalmic examination data, and brain magnetic resonance imaging data. Data were collected under the informed consent and confidentiality procedures approved by the institutional review board.
No publications or documents are linked to this record.
This study is completed, as verified in May 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Yuanpei University of Medical Technology