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RecruitingNCT07606547Updated Jun 3, 2026

Biomechanical Effects of EMST® on Swallowing Function in Parkinson's Disease

An interventional study of exspiratory muscle strength training in Parkinson's Disease (PD) and Dysphagia, sponsored by University Hospital Muenster. Recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-03.

Sponsored by University Hospital Muenster · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this non-randomized intervention study is to investigate the detailed effects of a structured four-week EMST® training program on the biomechanics of swallowing function in dysphagic Parkinson's patients. A combination of fiberoptic endoscopic evaluation of swallowing (FEES) and pharyngeal high-resolution manometry (HRM) will be employed to comprehensively evaluate the neuromuscular changes in swallowing.

02

Conditions studied

  • Parkinson's Disease (PD)
  • Dysphagia

Keywords

  • Dysphagia
  • Expiratory muscle strength training
  • Parkinson's Disease
  • High-resolution pharyngeal manometry
03

In context

Parkinson Disease

4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.

This study's planned enrollment of 30 is below the median of 40 across 3,353 interventional studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

University Hospital Muenster is the lead sponsor of 192 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diagnosis of Parkinson's disease,
  • PD-related dysphagia as objectively diagnosed with FEES

Exclusion criteria

Exclusion Criteria:

  • severe dementia, not able to give consent
  • dysphagia related to other diagnoses
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    EMST treatment

    daily EMST training on 5 days a week for 1 month

    Device: exspiratory muscle strength training

Interventions

  • Deviceexspiratory muscle strength training

    5 sets of 5 breaths with EMST per day, 5 days a week for 1 month

    Also known as: EMST

06

What researchers measure

Primary outcomes

  1. Effect on swallowing biomechanics in pharyngeal high-resolution manometry as assessed by measurement of e.g. Pharyngeal contractile Integral (PhcI)

    metrics of pharyngeal contraction and upper esophageal sphinkter opening in high-resolution pharyngeal manometry

    Time frame: 1 month and 3 months

Secondary outcomes

  1. Pharyngeal swallowing safety and efficiency as assessed with fiberoptic endoscopic evaluation of swallowing (FEES) applying DIGEST-FEES scoring

    Assessment of Swallowing safety and efficiency with DIGEST-FEES (Dynamic Imaging Grade of Swallowing Toxicity - FEES), Range 0 (best) - 4 (worst)

    Time frame: 1 month and 3 months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07606547
Responsible party
Sponsor
First posted
May 26, 2026
Start date
Jun 2026 (estimated)
Primary completion
May 2028 (estimated)
Completion
May 2028 (estimated)
Last update
Jun 3, 2026

Study contacts

Sonja Suntrup-Krueger, Prof. Dr. med.
Contact
sonja.suntrup-krueger@ukmuenster.de
+49251-83-46811
Sonja Suntrup-Krueger, Prof. Dr. med.
study chair · University Hospital Münster, Department of Neurology, Albert-Schweitzer-Campus 1, A1, 48149 Münster, Germany

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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