An interventional study of Corvis Machine in Keratoconus and Intraocular Pressure, sponsored by Tanta University. Not yet recruiting. Open to participants aged 19 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-20.
Sponsored by Tanta University · Not applicable, Interventional, and Diagnostic
To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.
This study will be prospective study. 50 Patients will be included who will undergo corneal cross linking from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study .
Patient with age 19 till 35 years old will be included
Patient with Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study
All patient will undergo full ophthalmological examination. including best corrected visual acuity, degree of myopia , average kertometry and intraocular pressure will be measured before and after cross linkage with three different techniques including Shiotz tonometry, appalanation tonometry and CORVIS machine
313 studies on the registry are indexed under Keratoconus; 56 are open to participants now.
This study's planned enrollment of 1 is below the median of 40 across 205 interventional studies indexed under Keratoconus.
Browse Keratoconus studies →Tanta University is the lead sponsor of 1,010 studies on the registry; 321 are open to participants now.
Of its 15 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
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Exclusion Criteria:
Measuring the intraocular pressure by using different techniques after corneal cross linking
Device: Corvis Machine
Measuring the intraocular pressure
Intraocular pressure will be measured by using Corvis CT before cross linking and one month after cross linking
Recording the intraocular pressure
Time frame: Through the end of the study in approximately one year
No study locations are listed for this record.
Plan to share: Yes — The statistical analysis results will be shared through the manuscript
Start is estimated for Jul 2026; primary completion for Dec 2026, 5 months later.
Of 59 non-industry interventional studies with no phase under Keratoconus, half reached primary completion within 34 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 54. This study's planned 5 months is below that.
Counting every sponsor, half of 68 studies reached it within 34 months; a quarter within 12 and three quarters within 59.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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