An observational study in AKI - Acute Kidney Injury and Critical Illness, sponsored by Karolinska Institutet. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-18.
Sponsored by Karolinska Institutet · Observational
Among 10 studies in Acute Kidney Injury by Karolinska Institutet — 4 open to participants now, 5 under way, none of them phase 3. Acute Kidney Injury · Karolinska Institutet.
Among the 10 studies in Acute Kidney Injury by Karolinska Institutet, this one is one of 2 that started in 2026, is one of 9 observational ones, and was the 9th registered.
1,691 studies on the registry are indexed under Acute Kidney Injury; 395 are open to participants now.
Browse Acute Kidney Injury studies →4 of the 10 studies in Acute Kidney Injury by Karolinska Institutet are open now, in 1 country. Recruiting first, the newest first:
Karolinska Institutet · Sites in Sweden
Ages 18+
Karolinska Institutet · Sites in Sweden
Ages 18+
Karolinska Institutet
Ages 18+
By country, each count listing its studies:
Of the 230 Acute Kidney Injury studies recruiting now, 161 (70%) set no upper age limit and 36 (16%) stop at 75 or younger; 22 take children under 18; 25 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
10 studies; the count open now beside each. This study's row is marked.
First in 2005; this study’s year is marked. 2 started in 2026.
This study's planned enrollment of 500,000 is above the median of 160 across 814 observational studies indexed under Acute Kidney Injury.
Median enrollment 10,000 across the 1 interventional studies, 22,000 across the 9 observational. Of the 4 that completed or were terminated, 0 (0%) have results posted.
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Karolinska Institutet is the lead sponsor of 1,149 studies on the registry; 277 are open to participants now.
2 of the studies in Acute Kidney Injury by Karolinska Institutet that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07013175Karolinska InstitutetWise Choices in the Intensive Care Unit | 2026-12-31 |
| NCT07093684Karolinska InstitutetDementia and Kidney Disease: Epidemiological Approaches to Risk Factors and Treatment Strategies | 2026-12-31 |
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Among the 10 studies in Acute Kidney Injury by Karolinska Institutet, from their registry updates:
Nothing recorded among them since 2026-09-25.
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This large national cohort study, including over 500,000 patients, where around 5% are treated with continuous renal replacement therapy (CRRT) , aims to evaluate the association between time to initiation of CRRT and intensive care unit (ICU) length of stay (LOS).
This large national cohort study, including over 500,000 patients, aims to evaluate the association between time to initiation of continuous renal replacement therapy (CRRT) and intensive care unit (ICU) length of stay (LOS).
The investigators hypothesize that earlier start of CRRT is associated with shorter length of stay among critically ill patients.
CRRT is seen as a costly intervention, and after studies failing to demonstrate a mortality benefit from earlier initiation, the trend is to push, or postpone the start of CRRT. In Sweden the additional cost of CRRT amounts to around 5000 SEK, approximately 500 dollars/euros per 24 hours. However, the 24-hour cost of staying in the ICU is around 58000 SEK or 5800 dollars/euros.
All adult critically ill patients in Swedish ICUs from 2010-2023, with- and without the need of CRRT forms this cohort.
Within the cohort, a nested case-control type of study can be performed. Two groups:
Group 1: Patients with CRRT initiation time less than 30 hours (early CRRT) Group 2: Patients with CRRT initiation time 30 hours or more (late CRRT)
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
*Patients under 18 years of age
We are evaluting early vs late initiation of CRRT
Intensive care unit (ICU) length of stay (LOS) measured in hours
Hours from baseline, i.e. ICU admission (time=0) to ICU discharge (time=0+hours in ICU)
Time frame: ICU LOS during the study period, from admission to discharge, average 168 hours (one week)
Mortality
Days from baseline, i.e. ICU admission to 30, 90,180 and 365 day mortality
Time frame: ONE-YEAR Mortality post admission
Mechanical ventilation
Hours from baseline, i.e. start of ventilation (time=0) until end of ventilation, hours
Time frame: Time on mechanical ventilation during the study period, average one week, but up to ICU discharge
No study locations are listed for this record.
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No — Swedish law prohibits IPD sharing using extracted quality register data, when this has not been stated in the primary ethics application. However, other researchers can theoretically apply for data extraction from the Swedish Intensive Care Register.
Start is estimated for Nov 2026; primary completion for Dec 2027, 13 months later.
Of 349 non-industry observational studies under Acute Kidney Injury, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 42. This study's planned 13 months is below that.
Counting every sponsor, half of 364 studies reached it within 24 months; a quarter within 12 and three quarters within 42.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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