An interventional study of Micro-osteoperforations and Utility arch in Deep Bite Malocclusion, Intrusion of Tooth and Orthodontic Tooth Movement, sponsored by Al-Azhar University. Recruiting at 1 site in Egypt. Open to participants aged 15 Years to 25 Years. Per ClinicalTrials.gov, last updated 2026-05-05.
Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment
Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.
Micro-osteoperforations (MOPs) are a new, simple, and minimally invasive technique to accelerate tooth movement. The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increased bone resorption, the catabolic phase of tooth movement, in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement and decrease root resotption.
43 studies on the registry are indexed under Root Resorption; 9 are open to participants now.
This study's planned enrollment of 18 is below the median of 29 across 36 interventional studies indexed under Root Resorption.
Browse Root Resorption studies →Al-Azhar University is the lead sponsor of 531 studies on the registry; 172 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets with application of micro-osteoperforations above the apices of maxillary incisors.
Procedure: Micro-osteoperforations
Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets without application of micro-osteoperforations.
Device: Utility arch
Using utility arch with micro-osteoperforations (MOPs). The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increase bone resorption and the catabolic phase of tooth movement in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement at the apices above maxillary incisors to evaluate the amount of movement and amount of root resorption.
Also known as: MOPs
Patients will receive utility arch for intrusion of maxillary incisors without micro-osteoperforations.
Amount of root resorption
Time frame: Up to 6 months or correction of deep bite
Marginal bone level changes
Time frame: Up to 6 months or correction of deep bite
Amount of intrusion of maxillary incisors
Time frame: Up to 6 months or correction of deep bite
Plan to share: No — Data will not be shared due to privacy considerations.
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