An interventional study of Resistance exercise in Lymphedema, sponsored by Carsten Bogh Juhl. Recruiting at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-18.
Sponsored by Carsten Bogh Juhl · Not applicable, Interventional, and Supportive care
The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL). Additionally, the study will explore the immediate response in LLL to resistance exercise (2 hours and 24 hours post-exercise).
Participants will continously wear a circumfencential sensor at the calf (CIMON from Icompression) under a compression garment and an activity tracker (SENS Motion from SENS Innovation Aps) at the thigh for 3 periods (two with supervised exercise sessions of 2 weeks and one control period).
Participants will attend supervised resistance exercise 2-3 times per week for 2 periods of 2 weeks (one with compression garment and one without). Assessments with the principal investigator will be scheduled before and after every 2 week period. Participants will keep a digital diary or diary in paper of their lymphedema related symptoms and experienced issues with the sensors or app.
529 studies on the registry are indexed under Lymphedema; 131 are open to participants now.
This study's planned enrollment of 36 is below the median of 50 across 369 interventional studies indexed under Lymphedema.
Browse Lymphedema studies →Carsten Bogh Juhl is the lead sponsor of 3 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Neoadjuvant treatment is given before the main treatment (usually surgery), often to shrink a tumour. Adjuvant treatment is given after it, to lower the chance of the cancer coming back.
Adjuvant and neoadjuvant
Neoadjuvant treatment is given before the main treatment (usually surgery), often to shrink a tumour. Adjuvant treatment is given after it, to lower the chance of the cancer coming back.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Week 1-2 no exercise, week 3 washout, week 4-5 exercise without compression, week 6 washout, week 7-8 exercise with compression
Other: Resistance exercise
Week 1-2 exercise without compression, week 3 washout, week 4-5 exercise with compression, week 6 washout, week 7-8 no exercise
Other: Resistance exercise
Week 1-2 exercise with compression, week 3 washout, weekend 4-5 no exercise, week 6 washout, week 7-8 exercise without compression
Other: Resistance exercise
Supervised resistance exercise targeted at the larger muscle groups in the lower limbs, 5 exercises, 3 sets of 10RM
Lower leg circumference
circumferential sensor CIMON, measured in Picoferens (pF)
Time frame: 14 days
Lower Limb volume
perometry, volume (mL)
Time frame: 14 days
Lower Limb volume
circumferential measurements, 8 cm interval, converted to volume (mL)
Time frame: 14 days
Edema of the foot and ankle
Figure of eight with tape measure, (cm)
Time frame: 14 days
Extracellular fluid of the lower limb
Bioimpedance Spectroscophy, (L-dex)
Time frame: 14 days
Body composition
Bioimpedance Spectroscophy, One measurement provides the following data: Total Body Water (L/%) , Extracellular fluid (L/%), Intracellular fluid (L/%), Skeletal muscle mass (kg/%), Fat mass (kg/%), Fat free mass (kg/%)
Time frame: 14 days
Segmental body composition of the lower limbs
Bioimpedence Spectroscophy, One measurement provides the following data: Total Body water (L), Extracellular fluid (L), Intracellular fluid (L), Skeletal Muscle Mass(kg), Lean soft tissue (kg)
Time frame: 14 days
Self reported lymphedema symptoms
Pain, tension, heaviness, tinkling, numeric ranking scale 0-10
Time frame: 14 days
Physical activity
Daily number of minutes in activity (defined as the sum of time spent with standing, walking, cycling and high intensity activity) registered by a activity sensor (SENS Motion). Level of physical activity time per 24 hours at the following categories: lying, sitting, standing, walking, brisk walking, biking, high intensity activity
Time frame: 14 days
Adverse events
E.g. skin irritation, cellulitis, severe muscle injury, number of events
Time frame: 14 days
Adherence to compression
Adherence to compression garments = 7 days a week, yes or no, if no - number of days with compression per participant
Time frame: 14 days
Adherence to study
Completion of supervised exercise sessions and application of the sensors, number of exercise sessions attended and number of days with sensors applied per participant
Time frame: 8 weeks
Withdrawal from study
Number of participants and reasons for withdrawal
Time frame: 8 weeks
Adherence to study
Completion of supervised exercise sessions and application of the sensors, number of exercise sessions attended and number of days with sensors applied
Time frame: 8 weeks
Plan to share: No
No publications or documents are linked to this record.
Started May 2026 (actual). Primary completion is estimated for Mar 2027, 10 months after the start.
Of 175 non-industry interventional studies with no phase under Lymphedema, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 68. This study's planned 10 months is below that.
Counting every sponsor, half of 197 studies reached it within 25 months; a quarter within 9 and three quarters within 64.
How these figures are worked out, and which studies are left out of them.
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Carsten Bogh Juhl