ClinicalTrials.gg
RecruitingNCT07544303MSUpdated Apr 22, 2026

Fatigue and Mental Well-Being in MS Patients(Multiple Sclerosis)

An interventional study of Quran recital in Multiple Sclerosis, sponsored by Artvin Coruh University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-04-22.

Sponsored by Artvin Coruh University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Primary completion was expected by May 2026, 5 months ago, but the record still lists the study as recruiting.
  • Started Sep 2025; still recruiting 1 year 2 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
52
Allocation
Randomized
Ages
18 Years to 80 Years
Sex
All
01

Study summary

This study will be conducted to evaluate the effects of Quran recital on fatigue and mental well-being in patients with multiple sclerosis.

Hypotheses:

  1. Quran recital reduces fatigue in MS patients.
  2. Quran recital increases mental well-being in MS patients. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.
Read the detailed description

50 patients who meet the inclusion criteria and voluntarily agree to participate in the study will be determined. These patients will be informed about the study and their consent will be obtained. These patients will then be randomized into the Quran recital group and the control group. Personal and contact information of the patients will be recorded and pre-test forms will be applied. The Quran recital group will be asked to listen to the Quran for half an hour with an mp3 player given to them 3 days a week (Monday-Wednesday-Friday) between 21:00-22:00 and this practice will be continued for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.

02

Conditions studied

  • Multiple Sclerosis

Keywords

  • multiple Sclerosis,
  • Quran,
  • fatigue,
  • mental well-being,
03

In context

Multiple Sclerosis

3,264 studies on the registry are indexed under Multiple Sclerosis; 659 are open to participants now.

This study's planned enrollment of 52 is close to the median of 50 across 2,201 interventional studies indexed under Multiple Sclerosis.

Browse Multiple Sclerosis studies →

Lead sponsor

Artvin Coruh University is the lead sponsor of 29 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Having been diagnosed with Multiple Sclerosis at least 6 months ago
  2. Being between the ages of 18-80
  3. Agreeing to participate in the research
  4. Not having any obstacles to wearing headphones
  5. Not having any hearing problems

Exclusion criteria

Exclusion Criteria:

  1. Those with major psychiatric disorders
  2. Those with any obstacle to communication
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Single group
Masking
Double (Investigator, Outcomes assessor)
Enrollment
52 participants (estimated)

Study arms

  • Experimental
    Experimental group

    The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21:00-22:00 3 days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The final test measurements will be made at the end of the 4th week by interviewing the patients at the hospital.

    Behavioral: Quran recital

  • No intervention
    Control group

    Personal and contact information about the patients will be recorded and pre-test forms will be applied. The control group will continue their routine treatment and care and no additional intervention will be applied. Post-test measurements will be made by meeting with the patients at the hospital at the end of the 4th week.

Interventions

  • BehavioralQuran recital

    The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21.00-22.00 three days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks.

06

What researchers measure

Primary outcomes

  1. Fatigue Impact

    The Fatigue Impact Scale (FIS)

    Time frame: 1 mount

Secondary outcomes

  1. Fatigue Severity Warwick-Edinburgh Mental Well-Being Scale

    The Fatigue Severity Scale (FSS)

    Time frame: 1 mount

07

Study locations

1 of 1 sites recruiting
  • Van Yüzüncü Yıl University Dursun Odabaş Medical Center
    Van, 65200, Turkey (Türkiye)
    Recruiting
    • Yavuz Üren, Asst. Prof · Contact
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Sep 2025 (actual). Primary completion is estimated for May 2026, 8 months after the start.

Of 847 non-industry interventional studies with no phase under Multiple Sclerosis, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 43. This study's planned 8 months is below that.

Counting every sponsor, half of 869 studies reached it within 21 months; a quarter within 9 and three quarters within 43.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 4, 2025
First posted
Apr 22, 2026
StartActual
Sep 9, 2025
Primary completionEst.
May 15, 2026
CompletionEst.
May 15, 2026
Last update
Apr 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 22, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07544303
Lead sponsor
Artvin Coruh University
Responsible party
Sevgi DEMIR CAM (Asst. Prof. Dr, Artvin Coruh University) — Principal investigator
First posted
Apr 22, 2026
Start date
Sep 9, 2025
Primary completion
May 15, 2026 (estimated)
Completion
May 15, 2026 (estimated)
Last update
Apr 22, 2026

Study contacts

SEVGİ DEMİR ÇAM, Asst. Prof
Contact
sevgidemir91@hotmail.com
905073468284
Yavuz Üren, Asst. Prof
Contact
yavuzuren@yyu.edu.tr
905065961050
Sevgi Demir Cam, Asst. Prof
study chair · Artvin Çoruh University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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