An observational study in Neurodevelopmental Disorders, sponsored by University Hospital, Tours. Recruiting at 1 site in France. Open to participants aged 6 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-06-16.
Sponsored by University Hospital, Tours · Observational
The goal of this observational study is to evaluate intra-individual neurophysiological variability in children and adults with and without NeuroDevelopmental Disorders (NDD), for several sensory modalities and types of stimulation. The main hypotheses are:
Participants in this study will:
These evaluations will be split in 3 visits spread on a maximum of 3 months, and training for learning will be done at home in between 2 visits.
352 studies on the registry are indexed under Neurodevelopmental Disorders; 141 are open to participants now.
This study's planned enrollment of 200 is close to the median of 200 across 133 observational studies indexed under Neurodevelopmental Disorders.
Browse Neurodevelopmental Disorders studies →University Hospital, Tours is the lead sponsor of 307 studies on the registry; 79 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Participants will be adults between 18 and 45 years old and children between 6 and 12 years old, with or without a Neurodevelopmental Disorder.
Inclusion Criteria:
Non-inclusion Criteria:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
6-12 years old children
18-45 years old adults
6-12 years old children
18-45 years old adults
Amplitude of central neurophysiological responses to sensory stimulations
Amplitude (in micro-volts) of event-related potentials
Time frame: Through study completion, an average of 2 months per participant
Latency of central neurophysiological responses to sensory stimulations
Latency (in milli-seconds) of event-related potentials
Time frame: Through study completion, an average of 2 months per participant
Variability of central neurophysiological responses to sensory stimulations
Intra-individual variability (in percentage) of event-related potentials
Time frame: Through study completion, an average of 2 months per participant
Visual perceptual learning performance
Discrimination performance (in percentage) for visual delayed-matching to sample task
Time frame: Through study completion, an average of 2 months per participant
Auditory perceptual learning performance
Discrimination performance (in percentage) for auditory delayed-matching to sample task
Time frame: Through study completion, an average of 2 months per participant
Behavioral sensory profile
Score (in absolute score) for psychomotor evaluation (Échelle des Particularités Sensori-psychomotrices dans l'Autisme)
Time frame: Through study completion, an average of 2 months per participant
Sensory profile questionnaire
Score (in absolute score) for sensory questionnaire (Dunn Sensory Profile)
Time frame: Through study completion, an average of 2 months per participant
Cognitive psychological profile
Score (in absolute score) for cognitive test (Raven's Progressive Matrices)
Time frame: Through study completion, an average of 2 months per participant
Executive functions questionnaire
Score (in absolute score) for executive functions questionnaire (BRIEF or BRIEF-A depending on the group)
Time frame: Through study completion, an average of 2 months per participant
Attentional functions questionnaire
Score (in absolute score) for attentional functions questionnaire (SNAP-IV-26 or ASRS-V1.1 depending on the group)
Time frame: Through study completion, an average of 2 months per participant
Socio-emotional questionnaire
Score (in absolute score) for socio-emotional questionnaire (AQ)
Time frame: Through study completion, an average of 2 months per participant
Linguistic profile
Score (in absolute score) for non-words and sentences repetition (LITMUS)
Time frame: Through study completion, an average of 2 months per participant
Heart beat response to sensory stimulations
Heart beat variation (in milliseconds) following sensory stimulation, recorded simultaneously with EEG
Time frame: Through study completion, an average of 2 months per participant
Electrodermal activity response to sensory stimulations
Electrodermal activity variation (in microsiemens) following sensory stimulation, recorded simultaneously with EEG
Time frame: Through study completion, an average of 2 months per participant
Pupillary response to sensory stimulations
Pupillary diameter variation (in millimeter) following sensory stimulation,recorded simultaneously with EEG
Time frame: Through study completion, an average of 2 months per participant
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Neurodevelopmental Disorders →