An interventional study of light-blocking lenses and single-vision lenses in Anisometropia and Hyperopia, sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University. Not yet recruiting at 1 site in China. Open to participants aged 6 Years to 12 Years. Per ClinicalTrials.gov, last updated 2025-08-27.
Sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University · Not applicable, Interventional, and Treatment
To evaluate the effectiveness of light-blocking lenses in promoting emmetropization and reducing anisometropia in children with hyperopic anisometropia, and to assess the impact of light-intercepting lenses on visual function in this population.
31 studies on the registry are indexed under Anisometropia; 10 are open to participants now.
This study's planned enrollment of 90 is above the median of 58 across 24 interventional studies indexed under Anisometropia.
Browse Anisometropia studies →Zhongshan Ophthalmic Center, Sun Yat-sen University is the lead sponsor of 164 studies on the registry; 80 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The eye with higher hyperopia will be fitted with light-blocking lenses for full-time wear, while the fellow eye with lower hyperopia will be fitted with conventional single-vision lenses for full-time wear, over 12 months. Follow-up visits will be scheduled at 6 months (±15 days) and 12 months (±15 days) after lens fitting. Lens replacement will be arranged if a refractive change greater than 0.50 diopters occurs or if the lenses become severely damaged
Other: light-blocking lenses
Both eyes of the subjects will be fitted with conventional single-vision lenses for full-time wear over 12-months. Follow-up visits will be scheduled at 6 months (±15 days) and 12 months (±15 days) after lens fitting. Lens replacement will be arranged if a refractive change greater than 0.50 diopters is detected or if the lenses become severely damaged.
Other: single-vision lenses
The eye with higher hyperopia will be fitted with light-blocking lenses for full-time wear, while the fellow eye with lower hyperopia will be fitted with conventional single-vision lenses for full-time wear, over 12 months
Both eyes of the subjects will be fitted with conventional single-vision lenses for full-time wear over 12 months.
Axial length
measured by optical biometer
Time frame: At baseline, 6 months, and 12 months
Refractive error
measured by cycloplegic refraction
Time frame: At baseline, 6 months, and 12 months
Best-corrected visual acuity
measured by visual acuity chart
Time frame: At baseline, 6 months, and 12 months
Intraocular pressure
measured by non-contact tonometer
Time frame: At baseline, 6 months, and 12 months
Angle of deviation
measured by alternate cover test with prism
Time frame: At baseline, 6 months, and 12 months
Contrast sensitivity
measured by quick contrast sensitivity function test
Time frame: At baseline, 6 months, and 12 months
Stereopsis
measured by stereotest booklet
Time frame: At baseline, 6 months, and 12 months
Accommodative function
measured by phoropter
Time frame: At baseline, 6 months, and 12 months
Intervention questionnaire
measured by questionnaire
Time frame: At baseline, 6 months, and 12 months
Height
measured by ruler
Time frame: At baseline, 6 months, and 12 months
Weight
measured by weighing scale
Time frame: At baseline, 6 months, and 12 months
Choroidal thickness (optional)
measured by OCT, optional
Time frame: At baseline, 6 months, and 12 months
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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Zhongshan Ophthalmic Center, Sun Yat-sen University →