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Enrolling by invitationNCT06744478Updated Dec 20, 2024

Assessing the Magnitude of Anisometropia in Patients Wearing Misight 1 Day Contact Lens

An observational study in Myopia and Anisometropia, sponsored by Buddhist Tzu Chi General Hospital. Enrolling by invitation at 1 site in Taiwan. Open to participants aged 8 Years to 23 Years. Per ClinicalTrials.gov, last updated 2024-12-20.

Sponsored by Buddhist Tzu Chi General Hospital · Observational

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as enrolling by invitation.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
50
Ages
8 Years to 23 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 39 studies in Myopia with a site in Taiwan — 6 open to participants now, 8 under way, none of them phase 3. Myopia · Taiwan.

Started
2025
with 2 others
Observational
9 of 39
1 open now
Registered
36th of 39
by date
Lead sponsor
2 of 39
Buddhist Tzu Chi General Hospital

Among the 39 studies in Myopia with a site in Taiwan, this one is one of 3 that started in 2025, is one of 9 observational ones, and was the 36th registered.

By phase

39 studies; the count open now beside each. This study's row is marked.

No phase22 · 5 open
Observationalthis study9 · 1 open
Phase 14 · 0 open
Phase 22 · 0 open
Phase 31 · 0 open
Phase 41 · 0 open

By the year they started

First in 2005; this study’s year is marked. 3 started in 2025.

Size and results

Median enrollment 69 across the 30 interventional studies, 100 across the 9 observational. Of the 19 that completed or were terminated, 0 (0%) have results posted.

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02

Study summary

The effectiveness of Misight 1 Day Contact Lens in retarding anisometropic progression has not been investigated before. This study is aimed to elucidate the efficacy of Misight 1 Day Contact Lens for anisometropia control.

03

Conditions studied

  • Myopia
  • Anisometropia
04

Who can participate

Ages eligible
8 Years to 23 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

We enroll the clinical patients who was diagnosed with anisometropia (meaning that myopia exceeds 100 degree diopters during the refraction examination, and the difference between the other eye is more than 100 degree diopters). Age limit was 8 to 23 years old. The purpose and process were carefully addressed to the subjects and their guardians who signed an informed consent form before commencing this study.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 8-23 years old children diagnosed with anisometropia and are willing to accept MiSight® 1 Day contact lens wearing treatment.
  • No congenital eye diseases or eye diseases such as strabismus and amblyopia.
  • Those who have been stated to be willing to participate in the program for at least 24 months and accept various evaluations.

Exclusion criteria

Exclusion Criteria:

  • Ocular surface disease( dry eye, keratoconus..)
  • Allergy to contact lens
  • Received eye surgery before
  • The cornea is infected (bacterial, fungal or viral infection).
  • Strabismus
  • Premature birth
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
50 participants (estimated)
Target follow-up
3 Months
Patient registry
Yes

Groups and cohorts

  • myopic children

    Myopic children use Misight 1 Day Contact Lens every day for myopia and anisometropia control.

    Device: Misight 1 Day Contact Lens

Interventions

  • DeviceMisight 1 Day Contact Lens

    Misight 1 Day Contact Lens wearing for myopia control

06

What researchers measure

Primary outcomes

  1. Changes of the visual acuity in myopic children with different Misight 1 Day Contact Lens

    The investigators measure the visual acuity of myopic children with different Misight 1 Day Contact Lens.

    Time frame: From the date of starting treatment, the visual acuity was measured 1 week, 1month and every 3 months up to 24 months.

Secondary outcomes

  1. Changes of axial length in myopic children with different Misight 1 Day Contact Lens

    The investigators measure the axial length(mm) of eyeball of myopic children with different diopter of Misight 1 Day Contact Lens.

    Time frame: From the date of starting treatment, the axial length was measured, then repeat measure were performed every 6 months up to 24 months

07

Study locations

1 site
  • Shang-Yen WU
    Hualien City, 97002, Taiwan
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jan 2025; primary completion for Dec 2025, 11 months later.

Of 87 non-industry observational studies under Myopia, half reached primary completion within 26 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 90. This study's planned 11 months is below that.

Counting every sponsor, half of 96 studies reached it within 24 months; a quarter within 10 and three quarters within 59.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 16, 2024
First posted
Dec 20, 2024
StartEst.
Jan 1, 2025
Primary completionEst.
Dec 31, 2025
CompletionEst.
Dec 31, 2026
Last update
Dec 20, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Dec 20, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06744478
Lead sponsor
Buddhist Tzu Chi General Hospital
Responsible party
Sponsor
First posted
Dec 20, 2024
Start date
Jan 1, 2025 (estimated)
Primary completion
Dec 31, 2025 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Dec 20, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Interested in this study?

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No contact was published for this record. The registry link below has the sponsor’s details.

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Discussion

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