ClinicalTrials.gg
CompletedNCT07528170KELSOUpdated Apr 14, 2026

Complications After CT-guided Lung Biopsies at St. Olavs Hospital

An observational study in Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care and Hemoptysis, sponsored by St. Olavs Hospital. Completed. Per ClinicalTrials.gov, last updated 2026-04-14.

Sponsored by St. Olavs Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,200
Sex
All
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Study summary

At St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study. The primary aim of this quality control study is to map complications in all patients who have undergone percutaneous CT-guided lung biopsy at St. Olavs Hospital from May 2012 to December 2023.

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Conditions studied

  • Pneumothorax Iatrogenic Postprocedural
  • Air Embolism as A Complication of Medical Care
  • Hemoptysis

Keywords

  • Lung cancer
  • CT-guided lung biopsy
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In context

Hemoptysis

37 studies on the registry are indexed under Hemoptysis; 6 are open to participants now.

This study's enrollment of 1,200 is above the median of 176 across 15 observational studies indexed under Hemoptysis.

Browse Hemoptysis studies →

Lead sponsor

St. Olavs Hospital is the lead sponsor of 171 studies on the registry; 29 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

1200

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients eligible to a CT-guided needle of a lung nodule (allcomers)

Exclusion criteria

Exclusion Criteria:

  • None
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Biopsy and archival tissue

A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.

Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,200 participants (actual)
Target follow-up
1200 Days
Patient registry
Yes

Groups and cohorts

  • CT-guided lung biopsy

    All patient with a lung nodule eligible for CT-guided needle biopsy

    Procedure: CT-guided needle biopsy of lung nodule

Interventions

  • ProcedureCT-guided needle biopsy of lung nodule

    This is a simple needle biopsy of lung nodules guided with CT imaging

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What researchers measure

Primary outcomes

  1. Pneumothorax

    The frequency of pneumothorax after lung biopsy

    Time frame: Patients are assessed with a CT scan 5 minutes after the lung biopsy

  2. Lung bleeding

    How frequent is parenchymal bleeding after lung biopsy

    Time frame: Patiens are assessed with a CT scan 5 minutes after the procedure

Secondary outcomes

  1. Factors associated with complications after lung biopsy

    Analyse possible factors leading to complications after lung biopsies

    Time frame: All patiens are assessed with CT scan 5 minutes after the lung biopsy

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Hajjar WM, Fetyani IM, Alqarni RM, Alajlan FA, Bahgat FF, Alharbi SR. Complications and Risk Factors of Patients Undergoing Computed Tomography-Guided Core Needle Lung Biopsy: A Single-Center Experience. Cureus. 2021 Aug 5;13(8):e16907. doi: 10.7759/cureus.16907. eCollection 2021 Aug. PubMed 34513480 ↗
  • Heerink WJ, de Bock GH, de Jonge GJ, Groen HJ, Vliegenthart R, Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: meta-analysis. Eur Radiol. 2017 Jan;27(1):138-148. doi: 10.1007/s00330-016-4357-8. Epub 2016 Apr 23. PubMed 27108299 ↗

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from May 2012 to primary completion in Dec 2023, 139 months.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 7, 2026
First posted
Apr 14, 2026
StartActual
May 1, 2012
Primary completionActual
Dec 31, 2023
CompletionActual
Dec 31, 2023
Last update
Apr 14, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 14, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07528170
Lead sponsor
St. Olavs Hospital
Responsible party
Sponsor
First posted
Apr 14, 2026
Start date
May 1, 2012
Primary completion
Dec 31, 2023
Completion
Dec 31, 2023
Last update
Apr 14, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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