An interventional study of SOC (Standard of care) and Cold and Compression in High-grade Partial or Full Thickness Rotator Cuff Tears, sponsored by Ochsner Health System. Recruiting at 1 site in United States. Open to participants aged 35 Years and older. Per ClinicalTrials.gov, last updated 2026-04-14.
Sponsored by Ochsner Health System · Not applicable, Interventional, and Treatment
Among 350 studies in Acute Pain with a site in United States — 47 open to participants now, 52 under way, none of them phase 3. Acute Pain · United States.
Among the 350 studies in Acute Pain with a site in United States, this one is the 155th largest by planned enrollment of the 319 interventional ones that give a count, is one of 12 that started in 2026, is one of 122 with no phase, reaches primary completion later than 36 of the 51 other live ones, and was the 341st registered.
1,073 studies on the registry are indexed under Acute Pain; 166 are open to participants now.
Browse Acute Pain studies →47 of the 350 studies in Acute Pain with a site in United States are open now. Recruiting first, the newest first:
Duke University · Sites in United States
Florida State University · Sites in United States
Eli Lilly and Company · Sites in United States
Sparian Biosciences, Inc · Sites in United States
Children's National Research Institute · Sites in United States
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 101 Acute Pain studies recruiting now, 39 (39%) set no upper age limit and 49 (49%) stop at 75 or younger; 21 take children under 18; 24 take healthy volunteers.
This study: 35 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
350 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 30 · Phase 2 63 · Phase 3 47 · Phase 4 66
First in 2001; this study’s year is marked. 12 started in 2026.
This study's planned enrollment of 90 is close to the median of 86 across 902 interventional studies indexed under Acute Pain.
Median enrollment 82 across the 319 interventional studies, 100 across the 31 observational. Of the 265 that completed or were terminated, 131 (49%) have results posted.
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77 of 350 have an industry lead sponsor. The 10 most frequent:
Ochsner Health System is the lead sponsor of 57 studies on the registry; 7 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Ochsner Health System has 2 studies filed under Acute Pain — fewer than ten, so there is no comparison to draw.
30 of the studies in Acute Pain with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07511816Eli Lilly and CompanyA Study of LY4515100 in Participants With Pain Following Third Molar Removal | 2026-11 |
| NCT05335070Rutgers, The State University of New JerseyReducing Pain From Wisdom Molar Extractions | 2026-11 |
| NCT06795126Nationwide Children's HospitalLittle NIRVANA for Pediatric Pain and Anxiety | 2026-11-30 |
| NCT05458037Women and Infants Hospital of Rhode IslandRCT of Pain Perception With Fast and Slow Tenaculum Application | 2026-12 |
| NCT03408717KK Women's and Children's HospitalEvaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery | 2026-12-31 |
Among the 350 studies in Acute Pain with a site in United States, from their registry updates:
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The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14 days, then weekly after surgery for 3 months, and at 6 months post-surgery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Metastases
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients in this arm will receive standard therapy post-surgery and discharged with 28 hydrocodone/APAP 7.5 mg pills taken every 6 hours as needed (or its MME equivalent), 1 identical refill if patient calls, and cold therapy (bag of ice or gel pack)
Other: SOC (Standard of care)
Patients in this arm will be discharged with 28 hydrocodone/APAP 7.5 mg pills taken every 6 hours as needed (or its MME equivalent), 1 identical refill if patient calls, and cold \& compression therapy device provided by Sponsor)
Device: Cold and Compression
Patients enrolled in this arm will be discharged with 28 hydrocodone/APAP 7.5 mg pills taken every 6 hours as needed (or its MME equivalent), 1 identical refill if patient calls, and cold therapy (bag of ice or gel pack) Other Name:
External mechanical compression therapy (e.g., compression stockings) has been shown to reduce swelling and risk of deep vein thrombosis in the lower limbs following TKA.12,13 Combining advanced cryotherapy (continuous circulating cold flow) and dynamic compression may offer added benefits than either traditional cryotherapy (e.g., cold packs) or compression (e.g., stockings) alone.
PROMIS Pain NRS subscale
Compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups
Time frame: Enrollment to 6 months post RCR
Plan to share: Undecided — Currently there are no plans to share the data as there are no data sharing agreements in place with other institutions.
Started Mar 2026 (actual). Primary completion is estimated for Sep 2027, 18 months after the start.
Of 424 non-industry interventional studies with no phase under Acute Pain, half reached primary completion within 12 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 23. This study's planned 18 months is above that.
Counting every sponsor, half of 430 studies reached it within 11 months; a quarter within 5 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
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Ochsner Health System