An observational study in Acute Pain, Postoperative, Chronic Pain and Arthroplasty, Replacement, Knee, sponsored by Konya City Hospital. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-20.
Sponsored by Konya City Hospital · Observational
Among 21 studies in Pain, Postoperative by Konya City Hospital — 10 open to participants now, 10 under way, none of them phase 3. Pain, Postoperative · Konya City Hospital.
Among the 21 studies in Pain, Postoperative by Konya City Hospital, this one is one of 7 that started in 2026, is one of 4 observational ones, and was the 17th registered.
5,640 studies on the registry are indexed under Pain, Postoperative; 1,230 are open to participants now.
This study's planned enrollment of 220 is above the median of 102 across 683 observational studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →10 of the 21 studies in Pain, Postoperative by Konya City Hospital are open now, in 1 country. Each count lists the studies.
Of the 679 Pain, Postoperative studies recruiting now, 241 (35%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →21 studies; the count open now beside each. This study's row is marked.
First in 2021; this study’s year is marked. 7 started in 2026.
Median enrollment 70 across the 17 interventional studies, 168 across the 4 observational. Of the 11 that completed or were terminated, 0 (0%) have results posted.
Konya City Hospital is the lead sponsor of 81 studies on the registry; 23 are open to participants now.
6 of the studies in Pain, Postoperative by Konya City Hospital that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07511985Konya City HospitalEffect of Rebound Pain on Chronic Postsurgical Pain After Total Knee Arthroplasty | 2026-12-12 |
| NCT07124494Konya City HospitalRegional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction | 2026-12-12 |
| NCT07900997Konya City HospitalEffect of Sacral Erector Spinae Plane Block on Quality of Recovery After Cesarean Delivery: A Prospective Randomized Controlled Trial | 2027-05-01 |
| NCT07889869Konya City HospitalUltrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain | 2027-07 |
| NCT07720791Konya City HospitalAcetaminophen vs Placebo for Postoperative Analgesia After Abdominal Surgery | 2027-07-15 |
Among the 21 studies in Pain, Postoperative by Konya City Hospital, from their registry updates:
This prospective observational study aims to evaluate whether rebound pain after peripheral nerve block is associated with the development of chronic postsurgical pain following elective total knee arthroplasty. Adult patients undergoing unilateral total knee arthroplasty under spinal anesthesia and receiving a peripheral nerve block as part of routine multimodal analgesia will be included. No additional intervention, drug administration, or biological sampling will be performed beyond standard clinical care.
Rebound pain will be assessed during the early postoperative period using pain diaries, numeric rating scale pain scores, and analgesic consumption records. Chronic postsurgical pain and related outcomes will be evaluated at postoperative 3 and 6 months using validated instruments assessing pain severity, neuropathic pain features, psychological status, functional outcomes, and health-related quality of life. The primary outcome is the presence of chronic postsurgical pain at 3 months after surgery. Secondary outcomes include chronic pain at 6 months, pain intensity, neuropathic pain characteristics, opioid consumption, rescue analgesic requirements, sleep disturbance, and quality-of-life measures. The study also aims to explore demographic and clinical factors associated with rebound pain and chronic postsurgical pain.
Adult patients undergoing unilateral elective total knee arthroplasty at Konya City Hospital under spinal anesthesia and receiving a peripheral nerve block as part of routine multimodal analgesia.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants with a transition from well-controlled pain (Numeric Rating Scale \[NRS\] \<=3) to severe pain (NRS \>=7) within 0 to 48 hours after peripheral nerve block resolution.
Participants without a transition from well-controlled pain (Numeric Rating Scale \[NRS\] \<=3) to severe pain (NRS \>=7) within 0 to 48 hours after peripheral nerve block resolution.
Presence of Chronic Postsurgical Pain at 3 Months
Chronic postsurgical pain will be defined as pain developing or persisting after total knee arthroplasty that is not explained by another cause. Participants with pain and at least one Brief Pain Inventory-Short Form interference item score of 3 or higher at postoperative month 3 will be considered positive for chronic postsurgical pain.
Time frame: 3 months after surgery
Presence of Chronic Postsurgical Pain at 6 Months assessed by Brief Pain Inventory-Short Form (BPI-SF) interference score
Presence of chronic postsurgical pain at postoperative month 6 will be assessed using the same Brief Pain Inventory-Short Form (BPI-SF)-based study definition applied at month 3: pain not explained by another cause, NRS \>0, and at least one BPI-SF interference item score of 3 or higher.
Time frame: 6 months after surgery
Pain Intensity in the Early Postoperative Period
Pain intensity at rest and during movement will be assessed using the Numeric Rating Scale during the first 72 hours after surgery.
Time frame: 0 to 72 hours after surgery
Plan to share: No
No publications or documents are linked to this record.
Started Aug 2026 (actual). Primary completion is estimated for Dec 2026, 3 months after the start.
Of 391 non-industry observational studies under Pain, Postoperative, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 32. This study's planned 3 months is below that.
Counting every sponsor, half of 395 studies reached it within 13 months; a quarter within 5 and three quarters within 33.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Konya City Hospital