An interventional study of Standard Care Exercise Program (SC) and Functional Stabilization Training (FST) in Patellofemoral Pain Syndrome, sponsored by Ahram Canadian University. Active, not recruiting at 1 site in Egypt. Open to participants aged 18 Years to 35 Years. Per ClinicalTrials.gov, last updated 2026-10-28.
Sponsored by Ahram Canadian University · Not applicable, Interventional, and Treatment
The purpose of this study is to investigate the effects of a Functional Stabilization training program (FST) and a comprehensive corrective exercise program in PF pain and DKV.
PF pain impairs performance and quality of life and can predispose individuals to early PF osteoarthritis and Dynamic knee valgus has been identified as a modifiable risk factor for PF pain and serious knee injury .
Current rehabilitation strategies show mixed results. Solo hip strengthening programs may not correct Dynamic knee valgus. While both Functional Stabilization training (FST) and comprehensive corrective programs (CCEP) show potential benefits, direct comparisons are lacking. The FST suggested superior outcomes with functional training, but it did not specifically target DKV. Conversely, the CCEP demonstrated kinematic improvements, but included asymptomatic participants and lacked patient reported outcomes.
By directly comparing Functional Stabilization training (FST) with the CCEP, this study aims to provide clinicians with evidence based guidance on the most effective exercise strategy for improving lower limb kinematics and reducing pain. The findings could inform best practice guidelines and enhance outcomes.
297 studies on the registry are indexed under Patellofemoral Pain Syndrome; 74 are open to participants now.
This study's enrollment of 60 is above the median of 45 across 244 interventional studies indexed under Patellofemoral Pain Syndrome.
Browse Patellofemoral Pain Syndrome studies →Ahram Canadian University is the lead sponsor of 71 studies on the registry; 42 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A 0–100 scale of how well someone can carry out everyday activities. 100 is no complaints and no signs of illness; 70 is able to look after yourself but not to work or keep up normal activity; 50 is needing considerable help and frequent medical care.
Studies often ask for 60 or 70 and above. Your doctor gives the score.
Karnofsky performance status (KPS)
A 0–100 scale of how well someone can carry out everyday activities. 100 is no complaints and no signs of illness; 70 is able to look after yourself but not to work or keep up normal activity; 50 is needing considerable help and frequent medical care.
Studies often ask for 60 or 70 and above. Your doctor gives the score.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Standard care exercise program for patellofemoral pain. Participants receive 24 supervised sessions (3 sessions/week for 8 weeks), \~45-60 minutes/session." (If you want 1 extra line: "Exercises follow a conventional PFP program based on Baldon et al.")
Behavioral: Standard Care Exercise Program (SC)
Functional stabilization/neuromuscular training to optimize movement patterns and dynamic alignment. 24 supervised sessions (3/week for 8 weeks), \~45-60 minutes/session. Includes warm-up/cool-down (\~15 min) and \~45 min exercises. Intensity/progression increases every 2 weeks; exercises progress from \~2 sets (10-20 reps) with \~5-sec isometric holds to \~3 sets of \~12 reps with \~10-sec holds and added external load (weights/elastic resistance)
Behavioral: Functional Stabilization Training (FST)
Comprehensive corrective exercise program targeting strength, flexibility, neuromuscular control, and alignment across the kinetic chain for dynamic knee valgus. 24 supervised sessions (3/week for 8 weeks), \~45-60 minutes/session. Three phases: weeks 1-2 sensorimotor/non-weight-bearing alignment + feedback + isometrics; weeks 3-6 progressive weight-bearing with increased load/complexity and emphasis on co-contraction/reciprocal activation; weeks 7-8 functional tasks to maintain gains and challenge multi-planar control. Visual/verbal/tactile feedback provided; progression only with correct technique
Behavioral: Comprehensive Corrective Exercise Program (CCEP)
Supervised standard care exercise therapy for patellofemoral pain, delivered 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session.
Supervised functional stabilization/neuromuscular exercise program focusing on lower-limb alignment and movement control. 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session, progressive difficulty/load
Also known as: Neuromuscular training
Supervised comprehensive corrective exercise program targeting flexibility, strength, and neuromuscular control across the kinetic chain to address dynamic knee valgus. 3 sessions/week for 8 weeks (24 sessions), \~45-60 minutes/session, phase-based progression
Change From Baseline in Peak Knee Abduction Angle During Single-Leg Squat and Drop Vertical Jump Landing
Peak knee abduction (valgus) angle, in degrees, of the \[dominant\] limb, measured with a 3D motion capture system (Vicon) during two tasks: single-leg squat and drop vertical jump landing. For each task, the peak value is averaged across \[3\] trials, and change is calculated as the Week 8 value minus the baseline value. Results are reported separately for each task. Lower angles indicate less dynamic knee valgus, which is a better outcome; a negative change from baseline indicates improvement.
Time frame: Baseline and 8 weeks
Change From Baseline in Peak Hip Adduction Angle During Single-Leg Squat and Drop Vertical Jump Landing
Peak hip adduction angle, in degrees, of the \[dominant\] limb, measured with a 3D motion capture system (Vicon) during two tasks: single-leg squat and drop vertical jump landing. For each task, the peak value is averaged across \[3\] trials, and change is calculated as the Week 8 value minus the baseline value. Results are reported separately for each task. Lower angles indicate less hip adduction, which is a better outcome; a negative change from baseline indicates improvement.
Time frame: Baseline and 8 weeks
Change From Baseline in Peak Hip Internal Rotation Angle During Single-Leg Squat and Drop Vertical Jump Landing
Peak hip internal rotation angle, in degrees, of the \[dominant\] limb, measured with a 3D motion capture system (Vicon) during two tasks: single-leg squat and drop vertical jump landing. For each task, the peak value is averaged across \[3\] trials, and change is calculated as the Week 8 value minus the baseline value. Results are reported separately for each task. Lower angles indicate less hip internal rotation, which is a better outcome; a negative change from baseline indicates improvement.
Time frame: baseline and 8 weeks
Kujala Patellofemoral Scale (KPS)
Change from baseline to 8 weeks in patient-reported knee function measured using the Arabic Kujala Patellofemoral Scale (0 to 100). Higher scores indicate better knee function and fewer patellofemoral symptoms.
Time frame: Baseline and 8 weeks
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Patellofemoral Pain Syndrome →
Ahram Canadian University