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CompletedNCT07422415Updated Feb 20, 2026

Effects of E-Cigarette Use Among Young Egyptian Adults

An observational study in E Cigarette Use, sponsored by Mansoura University Hospital. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-20.

Sponsored by Mansoura University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
104
Ages
18 Years and older
Sex
All
01

Study summary

Electronic cigarettes (E-cigarettes) have gained significant popularity as an alternative to traditional combustible tobacco cigarette smoking. E-cigarettes are marketed as a safer alternative to conventional smoking forms. Many chronic smokers suppose that e-cigarettes are risk-free and can be used effectively as a smoking cessation tool. The market size of e-cigarette is increasing because of its rising popularity among the youth even though it is not an approved Food and Drug Administration (FDA) product yet

Read the detailed description

Most daily life activities as walking and household chores that affect quality of life are performed at a submaximal level of exertion. E-cigarettes may affect overall physical fitness and cardiovascular health. It is important to evaluate responses of all body systems interacting during exercise, including cardiovascular and pulmonary function, systemic circulation, peripheral circulation, blood, neuromuscular units, muscle metabolism, oxygen transport and utilization within skeletal muscles. The knowledge gap regarding the potential negative health effects of E-cigarettes is crucial, as e-cigarettes are newly prevailing smoking tools that are gaining rising popularity among the youth. Additionally, the false perception of the unregulated electronic cigarette smoking as a safe recreational habit may increase the prevalence among the population. The aim of this work is to assess the clinical and functional impact of E-cigarettes garette use in young Egyptian adults, and to evaluate the role of chest CT in follow-up of identified abnormalities.

02

Conditions studied

  • E Cigarette Use

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Keywords

  • E-cigarettes
  • Vaping
03

In context

Vaping

160 studies on the registry are indexed under Vaping; 72 are open to participants now.

This study's enrollment of 104 is below the median of 120 across 23 observational studies indexed under Vaping.

Browse Vaping studies →

Lead sponsor

Mansoura University Hospital is the lead sponsor of 50 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

A total of 104 participants were enrolled and allocated into two equal groups: Group I: Exclusive e-cigarette users (n = 52) and Group II: Non-smoker controls (n = 52).

Inclusion criteria

  • Age > 18 years
  • E-cigarette users (≥6 months of regular use)
  • No prior history of chronic pulmonary disease

Exclusion criteria

Exclusion Criteria:

  • Dual users (both e-cigarettes and traditional tobacco)
  • History of chronic respiratory illnesses (e.g., asthma, COPD)
  • immunocompromised
  • Systemic chronic diseases
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
104 participants (actual)
Target follow-up
1 Month
Patient registry
Yes

Groups and cohorts

  • Non-smoker controls

    Patients were included with Age ≥ 18 years, Non smokers

    Diagnostic Test: Pulmonary Function test

  • Exclusive e-cigarette users

    Patients were included if Age ≥ 18 years, Exclusive e-cigarette users (Participants were considered exclusive e-cigarette users if they had used e-cigarettes regularly for ≥ 6 months).

    Diagnostic Test: Pulmonary Function test

Interventions

  • Diagnostic testPulmonary Function test

    Spirometry was performed measure forced expiratiory volume at 1st second (FEV₁), forced vital capacity (FVC), and FEV₁/FVC ratio.

06

What researchers measure

Primary outcomes

  1. Spirometer parameters assessment

    Spirometry was performed to measure forced expiratory volume at 1st second (FEV₁)

    Time frame: 3 months

  2. Spirometer assessment

    Spirometry was performed to measure FEV₁/FVC ratio

    Time frame: 3 months

  3. Spirometer

    Spirometry was performed to measure forced vital capacity (FVC)

    Time frame: 3 months

07

Study locations

1 site
  • Mohamed AbdElmoniem
    Al Mansurah, 35516, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 20, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07422415
Lead sponsor
Mansoura University Hospital
Responsible party
Mohamed Abd Elmoniem Mohamed (Lecturer faculty of medicine, Mansoura University Hospital) — Principal investigator
First posted
Feb 20, 2026
Start date
Sep 1, 2025
Primary completion
Dec 31, 2025
Completion
Feb 1, 2026
Last update
Feb 20, 2026

Study contacts

Mohamed AbdElmoniem
principal investigator · Lecturer of chest medicine faculty of medicine Mansoura university

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

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