ClinicalTrials.gg
Not yet recruitingNCT07400874Updated Feb 10, 2026

Use of Acupressure, Aromatherapy, and Virtual Reality for Children in During Blood Collection Procedures

An interventional study of Acupressure and Listening Music in Blood Collection, sponsored by Artvin Coruh University. Not yet recruiting. Open to participants aged 5 Years to 10 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-10.

Sponsored by Artvin Coruh University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Primary completion was expected by Jun 2026, 5 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
5 Years to 10 Years
Sex
All
01

Study summary

This study aims to evaluate the effects of acupressure, music listening, and virtual reality applications, which appeal to the senses of touch, hearing, and sight during blood sampling, on pain, fear, and anxiety levels in children.

Read the detailed description

Two hundred volunteer children aged 5-10 coming for blood collection will be randomly divided into four groups: acupressure, virtual reality, Listening music and control group. Children will be assessed before, during, and after the procedure. Pain related to blood collection will be assessed with the Wong-Baker Faces Pain Scale, fear will be assessed with the Child Fear Scale and anxiety will be assessed with the Child Anxiety Scale - State. In addition, children's demographic data will be recorded in the Information Form.

02

Conditions studied

  • Blood Collection

Keywords

  • Blood Collection
  • Fear
  • Pain
  • Anxiety
  • Acupressure
  • Virtual reality
  • listening music
  • child
03

In context

Pain

10,060 studies on the registry are indexed under Pain; 1,651 are open to participants now.

This study's planned enrollment of 120 is above the median of 66 across 8,497 interventional studies indexed under Pain.

Browse Pain studies →

Lead sponsor

Artvin Coruh University is the lead sponsor of 29 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
5 Years to 10 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Being between 5-10 years old Being healthy (no chronic disease diagnosis) Both child and parent agree to participate in the study Being able to communicate in Turkish Taking a blood sample in a single session Having no visual, auditory, or speech impairments, Being open to communication Being accompanied by a parent

Exclusion criteria

Exclusion Criteria:

Having an allergy to any substance Having a chronic illness (Type 1 diabetes, etc.) Having upper respiratory tract diseases such as asthma, rhinitis, pharyngitis Having an obstructive condition in the nasal passages for any reason Having vision or hearing loss Having any neuropathological problem Having complaints of vomiting, nausea, or pain Having recently used sedatives, anesthetics, or analgesics Having a chronic illness Having visual-auditory and speech impairments History of sedative, analgesic, or narcotic substance use within 24 hours prior to admission

05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
120 participants (estimated)

Study arms

  • No intervention
    Control Group

    Routine clinical care will be applied to the control group. No action will be taken.

  • Experimental
    Experimental Group

    Before blood is drawn, the child will undergo acupressure, watch a video through virtual reality glasses, and listen to music through headphones.

    Other: Acupressure · Other: Listening Music · Other: Virtual Reality

Interventions

  • OtherAcupressure

    Acupressure will be administered by a researcher who has completed the Acupressure application course at Ankara Başkent Personal Training Institutions and received their certificate. To determine the child's ability to assess the scale, they will be asked, "Is 8 bigger than 4?". Before the acupressure application, the child's area will be prepared in the blood collection room. Hands will be washed and warmed by rubbing before the acupressure application. Pressure will be applied for 1.5 minutes to point 4 of the large intestine (LI4), located on the radial side of the 2nd metacarpal bone, at the junction of the 1st and 2nd metacarpal bones, on the back of the hand. Then, the blood collection nurse will begin the blood collection procedure from the same arm. Pressure will continue for another 1.5 minutes while the blood collection procedure continues. In total, pressure will be applied to point LI4 for 3 minutes: 1.5 minutes before and 1.5 minutes during the procedure.

  • OtherListening Music

    Before the procedure, children will be given brief and understandable information, and if possible, calming and age-appropriate music will be chosen according to their musical preferences. The music will start 1-2 minutes before the procedure begins and continue through headphones or speakers during blood collection to distract the child's attention from the needle; it will also be played for another 1-2 minutes afterward to help the child relax and complete the procedure as a positive experience. During this process, the children's pain, fear, and anxiety levels will be measured.

  • OtherVirtual Reality

    In this study, children will be shown cartoons via virtual reality glasses during blood collection. For both boys and girls, the content options will be the 360-degree virtual reality cartoon "Ice Age," chosen by experts in child development and psychology to be age and gender-appropriate. The suitability of "Ice Age" for children was evaluated by five academics specializing in child health, and all experts deemed it appropriate. Children will begin watching the cartoon via VR approximately 3 minutes before blood collection and will continue watching until the procedure is complete.

06

What researchers measure

Primary outcomes

  1. 1. Patient Identification Form

    The form consists of a total of 7 questions covering the child's age, gender, previous hospital experience (if any), number of hospitalizations, whether their parents prepared them for blood tests beforehand, their experience with blood tests in the last six months, and their reactions to the blood test procedure.

    Time frame: Baseline

  2. Wong Baker Face Pain Scale

    Children between the ages of three and eight can express many pain areas and their severity. In this study, the Wong-Baker Pain Inventory will be used in combination with the Visual Analog Scale, since face scales are more appropriate. The Wong Baker Face Pain Scale was developed by Donna Wong and Connie Moran Baker in 1981. The scale is suitable for children between the ages of three and eighteen. The scale includes facial expressions that the child can enjoy and enjoy. For this reason, it has been stated that it gives more accurate results. The scale has scores of "0", "2", "4", "6", "8", and "10". A score of "0" indicates no pain and a score of "10" indicates the highest pain. This scale does not have a Cronbach's alpha score. It has been reported that reliability studies have not been conducted on such scales.

    Time frame: Baseline and up to 4 weeks

  3. 3. Child Fear Scale

    The Turkish validity of this scale, developed by McMurtry and colleagues, was done by Gerçeker and colleagues. The changes in the facial muscles of the frightened expression were drawn by a graphic artist from a photograph of a frightened face. It can be used by the parent, child or researcher to scale the child's fear. The scale, which has facial expressions scored from 0 to 4, is shown to the child. A score of 4 indicates that the child is very frightened, and a score of 0 indicates that the child is not frightened. It is accepted that a score of "0" indicates a neutral expression (no fear), a score of "1" indicates a very low level of fear, a score of "2" indicates a little fear, a score of "3" indicates a greater level of fear, and a score of 4 indicates that the level of fear is at the highest level. This scale can be used to measure fear before and during the procedure.

    Time frame: Baseline and up to 4 weeks

  4. 4. The Child Anxiety Scale-State (CAS-S)

    Developed by Ersig et al. in 2013, the Child Anxiety Scale-State measures situational anxiety in children aged 4-10 years. Its validity was established by Gerçeker et al. in 2017. The CAS-S (State) is designed as a thermometer. At the bottom is a bulb, and horizontal lines extend upwards. Each horizontal line represents a score, and the thermometer has 10 points. The bulb at the bottom represents 0 points, indicating no anxiety. As the lines rise, anxiety increases. The peak, worth 10 points, represents the highest level of anxiety.

    Time frame: Baseline and up to 4 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Oluc T, Sarialioglu A. The effect of a hand puppet-based therapeutic play for preschool children on the fear and pain associated with blood collection procedure. J Pediatr Nurs. 2023 Sep-Oct;72:e80-e86. doi: 10.1016/j.pedn.2023.06.012. Epub 2023 Jun 15. PubMed 37330277 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Mar 2026; primary completion for Jun 2026, 3 months later.

Of 3,734 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's planned 3 months is below that.

Counting every sponsor, half of 3,833 studies reached it within 10 months; a quarter within 4 and three quarters within 23.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 3, 2026
First posted
Feb 10, 2026
StartEst.
Mar 1, 2026
Primary completionEst.
Jun 1, 2026
CompletionEst.
Oct 1, 2026
Last update
Feb 10, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07400874
Lead sponsor
Artvin Coruh University
Responsible party
Gamze Akay (Assistant Professor, Artvin Coruh University) — Principal investigator
First posted
Feb 10, 2026
Start date
Mar 1, 2026 (estimated)
Primary completion
Jun 1, 2026 (estimated)
Completion
Oct 1, 2026 (estimated)
Last update
Feb 10, 2026

Study contacts

Gamze AKAY, 1
Contact
gamzeakay_25@artvin.edu.tr
+905314536661
Fahri AŞKAN, 2
Contact
fahriaskan@yyu.edu.tr
+90 541 221 05 07
Gamze AKAY, 1
principal investigator · Artvin Coruh University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion