ClinicalTrials.gg
Not yet recruitingNCT07931859Updated Nov 12, 2026

A Retrospective Study to Assess Patient-Reported Treatment Experience With Over-the-Counter Analgesic Products

An observational study in Pain, sponsored by HALEON. Not yet recruiting at 1 site in Singapore. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-11-12.

Sponsored by HALEON · Observational

Updated Nov 12, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
600
Ages
18 Years to 65 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 23 studies in Pain with a site in Singapore — 4 open to participants now, 7 under way, 2 of them phase 3. Pain · Singapore.

Started
2026
with 2 others
Observational
6 of 23
2 open now
Registered
23rd of 23
by date
Lead sponsor
2 of 23
HALEON

Among the 23 studies in Pain with a site in Singapore, this one is one of 3 that started in 2026, is one of 6 observational ones, and was the 23rd registered.

Pain

10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.

Browse Pain studies →

Open to participants now

4 of the 23 studies in Pain with a site in Singapore are open now. Recruiting first, the newest first:

All 4 open studies →

A study can be open while its sites in Singapore have not opened yet or have stopped. Only those recruiting at a site in Singapore →

Who these studies take

Of the 929 Pain studies recruiting now, 384 (41%) set no upper age limit and 434 (47%) stop at 75 or younger; 146 take children under 18; 222 take healthy volunteers.

This study: 18 Years to 65 Years · all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 23 studies in Pain with a site in Singapore, or all of them as a file.
02

Study summary

The primary purpose of this study is to evaluate the self-reported perceived onset and effectiveness of pain (headache/muscle ache) relief in overweight and obese adults currently on Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RA) therapy who have used Panadol Advance or Panadol ActiFast (or local equivalent variant) for occasional pain (headache/ muscle ache) relief in the past 1 month.

Read the detailed description

This is a real-world, observational, cross-sectional survey study of 600 participants aged 18-65 years old from the United Kingdom, Sweden, Colombia and Australia, who self-report using Panadol Advance or ActiFast (or local equivalent variant) for occasional pain relief in the past 1 month. Once eligibility is confirmed, participants will be directed to complete an online survey designed to gather data relevant to the research objectives.

03

Conditions studied

  • Pain

Browse trials for

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Resident of Australia/ United Kingdom/ Sweden/ Colombia who selfreport using Panadol Advance or ActiFast (or local equivalent variant) for occasional pain relief in the past 1 month.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Resident of Australia/ United Kingdom/ Sweden/ Colombia.
  • Is overweight ( [BMI] 25.0-29.9) or obese (BMI more than or equal to [>=]30.0), based on self-reported height and weight.
  • Self-reported to have used Panadol Advance or Panadol ActiFast (or local variant) at least once in the past 1 month for occasional pain (headache and/or muscle ache) relief.
  • Self-reported to be on GLP-1 RA medication (semaglutide, liraglutide, or tirzepatide) concurrently with Panadol Advance or Panadol ActiFast (or local variant) use.
  • Provided to participate.

Exclusion criteria

Exclusion Criteria:

  • Pregnant, breastfeeding, or planning to become pregnant in the past 1 month.
  • Used any other analgesic medication concurrently with Panadol Advance or Panadol ActiFast (or local equivalent variant) for the same pain episode (including prescription or OTC medicines).
  • Suffering from chronic illnesses such as chronic headache (occur 15 or more days per month and present for 3 months or longer), or Chronic Pain (Fibromyalgia, Neuropathy/ Nerve pain, Lupus, cancer, multiple sclerosis), severe liver impairment, or serious cognitive disorders diagnosed by a psychiatrist (for example [e.g.], major depressive disorder, schizophrenia, bipolar disorder).
  • or allergy to paracetamol.
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Hypersensitivity

An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
600 participants (estimated)
Patient registry
No

Groups and cohorts

  • Panadol Advance or Panadol ActiFast Tablet

    Participants who have used Panadol Advance or Panadol ActiFast (or local equivalent variant) for occasional pain (headache/ muscle ache) relief in the past one month.

    Drug: Paracetamol

Interventions

  • DrugParacetamol

    Paracetamol 500 milligram (mg) taken orally.

06

What researchers measure

Primary outcomes

  1. Perceived Onset of Relief After Product Use

    Thinking about the recent pain episode, participants will report approximate time for their pain to decrease after using the product.

    Time frame: Within the past 1 month from time of participation

  2. Perceived Relief From Product Use

    Thinking about the recent pain episode, participants will describe the first sign of symptom relief they perceived after using the product.

    Time frame: Within the past 1 month from time of participation

Secondary outcomes

  1. Characterization of the Pain Profile

    The information on pain such as type, frequency, severity, and duration will be collected from the participants.

    Time frame: Within the past 1 month from time of participation

  2. Quality of Life (QoL) Assessment Before and After Using the Product Post for Occasional Pain

    Thinking about most recent pain episode, participants will be asked to respond to QoL questions related to effect of pain on the aspects of their daily life before and after using the product. The responses will be scored using a 5-point scale, where 1= Not at all, and 5= Significantly. Lower score indicates better quality of life.

    Time frame: Within the past 1 month from time of participation

  3. Sources of Product Information and Trust in Product

    The information around sources of product information and how much does participants trust the product for mild to moderate or occasional pain relief will be collected.

    Time frame: Within the past 1 month from time of participation

  4. Product Switch Behaviors

    The information around the reasons for switching from the other brands will be collected.

    Time frame: Within the past 1 month from time of participation

  5. Perceived Difference in Speed of Analgesia Onset

    Participants will respond to a question- Compared with other brand(s) used in the past, how quickly does this product begin to relieve headache/ muscle ache. Response will be scored on scale 1= much faster to 5= much slower.

    Time frame: Within the past 1 month from time of participation

07

Study locations

1 site
  • Virtual Site
    Singapore, Singapore
08

References and documents

Individual participant data

Plan to share: Yes — Anonymized individual participant data and study documents can be requested for further research from ww.clinical-trial-register@haleon.com

Supporting information: Study protocol, Statistical analysis plan, Informed consent form

Time frame: IPD will be made available within 6 months of publishing the results of the primary endpoints, key secondary endpoints and safety data of the study.

Access criteria: Access is provided after a research proposal is submitted and has received approval from the Independent Review Panel and after a Data Sharing Agreement is in place. Access is provided for an initial period of 12 months, but an extension can be granted, when justified, for up to another 12 months.

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Nov 2026; primary completion for Dec 2026, 1 month later.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 6, 2026
First posted
Nov 12, 2026
StartEst.
Nov 2026
Primary completionEst.
Dec 2026
CompletionEst.
Dec 2026
Last update
Nov 12, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 12, 2026
Show all 1 update
  1. Nov 12, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07931859
Lead sponsor
HALEON
Responsible party
Sponsor
First posted
Nov 12, 2026
Start date
Nov 2026 (estimated)
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Nov 12, 2026

Study contacts

Haleon Response Center
Contact
ww.clinical-trial-register@haleon.com
+441932959500

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.

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Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

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