ClinicalTrials.gg
RecruitingNCT07356999EYAISUpdated May 26, 2026

Characterization of Visual Perception Impairments in Patients With Idiopathic Scoliosis

An interventional study of Motion Analysis in Idiopathic Scoliosis, sponsored by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française. Recruiting at 1 site in France. Open to participants aged 11 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-26.

Sponsored by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Started Apr 2026; still recruiting 6 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
70
Allocation
Not applicable
Ages
11 Years to 18 Years
Sex
All
01

Study summary

Scoliosis is more than just a curve in the spine; it is a complex, 3D twisting of the backbone. While it can be caused by birth defects or tumors, the most common type-idiopathic scoliosis-appears in healthy teenagers for no clearly known reason.

The Theory of Balance Researchers believe that scoliosis might actually be caused by a "glitch" in how the body stays upright. Instead of the spine curving on its own, the curve might be the body's way of compensating for a poor sense of balance.

To stay balanced, the human brain relies on three main "inputs":

  1. The Vestibular System: Located in the inner ear (detects movement).
  2. Proprioception: The body's "inner map" (sensing where your limbs are).
  3. Vision: Seeing the world around you to stay oriented.

The Goal of the Study Even though humans rely heavily on their eyes to stay balanced, the role of vision in scoliosis has not been studied very much.

This experiment aims to test the hypothesis that teenagers with scoliosis have trouble processing visual information to maintain their posture. By using advanced motion analysis, researchers want to see if a "misunderstanding" of visual cues is contributing to the spinal deformity.

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Conditions studied

  • Idiopathic Scoliosis

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03

In context

Scoliosis

660 studies on the registry are indexed under Scoliosis; 186 are open to participants now.

This study's planned enrollment of 70 is above the median of 45 across 386 interventional studies indexed under Scoliosis.

Browse Scoliosis studies →

Lead sponsor

Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française is the lead sponsor of 12 studies on the registry; 7 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
11 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Group Scoliosis:

  • Girls or boys aged 11 to 18 inclusive.
  • Patients with progressive idiopathic scoliosis
  • Candidates for either orthopedic (brace) or surgical (arthrodesis correction) treatment for which a pre-therapeutic multimodal assessment is planned.

Control group:

- Girls or boys aged 11 to 18 inclusive.

Exclusion criteria

Exclusion Criteria:

The following individuals will not be included:

  • Individuals with another musculoskeletal disorder.
  • Individuals with a neurosensory disorder that may affect the balance of the trunk or lower limbs.
  • Individuals with uncorrected visual perception disorders (visual check within 12 months prior to the examination).
  • Lack of consent from the subject.
  • Lack of consent from legal representatives.
  • Failure to understand the instructions for performing the tests.

In addition, for the control group:

- Suffering from scoliosis

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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
70 participants (estimated)

Study arms

  • Experimental
    Vertical Perception Assessment

    Other: Motion Analysis

Interventions

  • OtherMotion Analysis

    Researchers use motion capture to track exactly how a patient's body moves and shifts in response to different environments.

06

What researchers measure

Primary outcomes

  1. Margin of Dynamic Stability

    This measures how close a person is to losing their balance while moving. It calculates the distance between where the body's weight is moving and the edge of the person's "footprint" (base of support).

    Time frame: At enrollment

  2. Center of Pressure

    The point on the ground where the most weight is being concentrated. Tracking how much this point "wobbles" or shifts shows how hard the body is working to stay upright.

    Time frame: At enrollment

  3. Extrapolated Center of Mass

    A calculation that looks at both the position of the body and its velocity. It helps researchers predict if the person's momentum is about to carry them off-balance.

    Time frame: At enrollment

Secondary outcomes

  1. Base of Support

    The total area on the ground occupied by the feet. A wider BoS often suggests the subject is trying to create a "wider stance" to feel more stable.

    Time frame: At enrollment

  2. Visual Field Perception

    The "Distance Error." Using a joystick, the patient tries to place a 3D avatar exactly halfway between two other figures. The difference between the true middle and where the patient thinks the middle is reveals if their depth perception is distorted.

    Time frame: At enrollment

  3. Subjective Visual Vertical

    Angular Error. A glowing line is tilted on a screen, and the patient must tell the operator how to rotate it until it is perfectly vertical.

    Time frame: At enrollment

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Study locations

1 of 1 sites recruiting
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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Apr 2026 (actual). Primary completion is estimated for Sep 2027, 16 months after the start.

Of 223 non-industry interventional studies with no phase under Scoliosis, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 58. This study's planned 16 months is below that.

Counting every sponsor, half of 233 studies reached it within 22 months; a quarter within 8 and three quarters within 60.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 13, 2026
First posted
Jan 21, 2026
StartActual
Apr 21, 2026
Primary completionEst.
Sep 1, 2027
CompletionEst.
Sep 1, 2027
Last update
May 26, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 26, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07356999
Lead sponsor
Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Responsible party
Sponsor
First posted
Jan 21, 2026
Start date
Apr 21, 2026
Primary completion
Sep 1, 2027 (estimated)
Completion
Sep 1, 2027 (estimated)
Last update
May 26, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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