A Phase 3 interventional study of Volume-Stable Collagen Matrix in Gingival Recession, Localized, sponsored by Bulent Ecevit University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-15.
Sponsored by Bulent Ecevit University · Phase 3, Interventional, and Treatment
Among 69 studies in Gingival Recession with a site in Turkey — 14 open to participants now, 15 under way, none of them phase 3. Gingival Recession · Turkey.
Among the 69 studies in Gingival Recession with a site in Turkey, this one is the 2nd largest by enrollment of the 56 interventional ones that give a count, is one of 7 that started in 2022, is the only one in phase 3, and was the 52nd registered.
426 studies on the registry are indexed under Gingival Recession; 106 are open to participants now.
Browse Gingival Recession studies →14 of the 69 studies in Gingival Recession with a site in Turkey are open now. Recruiting first, the newest first:
Altinbas University · Sites in Turkey
Trakya University · Sites in Turkey
Zeliha Başak Çakır Erdil · Sites in Turkey
Kahramanmaras Sutcu Imam University · Sites in Turkey
Marmara University · Sites in Turkey
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 64 Gingival Recession studies recruiting now, 30 (47%) set no upper age limit and 31 (48%) stop at 75 or younger; 1 take children under 18; 36 take healthy volunteers.
This study: 18 Years and older · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
69 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 2 · Phase 3 1
First in 2010; this study’s year is marked. 7 started in 2022.
This study's enrollment of 60 is above the median of 30 across 390 interventional studies indexed under Gingival Recession.
Median enrollment 36 across the 56 interventional studies, 80 across the 13 observational. Of the 52 that completed or were terminated, 0 (0%) have results posted.
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None of the 69 has an industry lead sponsor. The 10 most frequent:
Bulent Ecevit University is the lead sponsor of 47 studies on the registry; 2 are open to participants now.
Bulent Ecevit University has 6 studies filed under Gingival Recession — fewer than ten, so there is no comparison to draw.
4 of the studies in Gingival Recession with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07804888Saglik Bilimleri UniversitesiEvaluation of the Effects of Injectable Platelet-Rich Fibrin and Hyaluronic Acid Treatments, Administered in Addition to Free Gingival Graft Therapy, on Clinical Healing. | 2027-01 |
| NCT07777185Ankara UniversityEvaluation of the Effect of Smoking on Palatal Donor Site Tissue Profile in the Success of Connective Tissue Grafts | 2027-02-20 |
| NCT07349056Trakya UniversityEarly Effects of Orthognathic Surgery on Periodontal Phenotype: A 6-Month Prospective Clinical and Radiographic Evaluation | 2027-02-23 |
| NCT07751211Altinbas UniversityEffects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft | 2027-03-06 |
Among the 69 studies in Gingival Recession with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
Comparison of Volume-Stable Collagen Matrix, Platelet-Rich Fibrin, and Subepithelial Connective Tissue Graft in the Treatment of Multiple Adjacent Gingival Recessions: A Parallel-Group, Randomized, Controlled Clinical Trial
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion criteria included:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The pre-prepared Volume Stable Collagen Matrix will be moistened with saline solution (SF) and placed beneath a coronally positioned flap at the recipient site during periodontal surgery.
Biological: Volume-Stable Collagen Matrix
Autologous platelet-rich fibrin (PRF) will be prepared from the patient's venous blood according to a standardized protocol and placed beneath a coronally advanced flap at the recipient site during periodontal surgery to enhance soft tissue healing and regeneration.
Biological: Volume-Stable Collagen Matrix
A subepithelial connective tissue graft harvested from the patient's palate and placed beneath a coronally positioned flap at the recipient site during periodontal surgery.
Biological: Volume-Stable Collagen Matrix
Volume-Stable Collagen Matrix
Percentage of Complete Root Coverage
Percentage of CRC will be calculated as: (number of teeth achieving complete root coverage) ÷ (total treated teeth)\] × 100
Time frame: 12 Months
Percentage of Mean Root Coverage
Percentage of root coverage will be calculated as: Percentage of root coverage: \[(preoperative recession depth - postoperative recession depth) ÷ preoperative recession depth\] × 100
Time frame: 12 months
Recession depth
RD will be measured from the cemento-enamel junction (CEJ) to the gingival margin and reported in millimeters (mm).
Time frame: 12 month
Probing depth
Probing depth will be measured from the gingival margin to the base of the sulcus and reported in millimeters (mm).
Time frame: 12 months
Clinical attachment level
Clinical attachment level will be measured from the cemento-enamel junction to the sulcus base and reported in millimeters (mm).
Time frame: 12 months
Keratinized gingiva width
KGW will be measured from the mucogingival junction to the gingival margin and reported in millimeters (mm).
Time frame: 12 months
Gingival Thickness
Gingival thickness (GT) will beevaluated at the mid-facial aspect, 2 mm apical to the gingival margin in the attached gingiva or alveolar mucosa, using a #15 endodontic spreader (Bahadır Diş, Istanbul, Turkey) with a rubber stopper under local anesthesia and reported in milimeters.
Time frame: 12 months
Postoperative Pain assessed using a Visual Analog Scale (VAS)
Postoperative pain will be assessed using a visual analog scale (VAS). Patients were asked to record the highest perceived pain each day from the day of surgery through the 10th postoperative day (total of 11 days).
Time frame: From the day of surgery through postoperative day 10 (11 days)
Dentin Hypersensitivity Score assessed using Air Stimulus (HSS)
Dentin hypersensitivity will be assessed using a 1-second air stimulus applied to the buccal surface of the treated tooth. Patients rated the perceived hypersensitivity on a numerical rating scale ranging from 0 (no hypersensitivity) to 10 (unbearable hypersensitivity).
Time frame: Baseline, 6 months, and 12 months
Pink Esthetic Score (PES) self-assessment
Esthetic outcomes will be evaluated using the Pink Esthetic Score (PES). Patients self-assessed gingival contour, gingival color, and overall esthetic appearance using a numerical rating scale ranging from 0 (unpleasant) to 10 (excellent).
Time frame: Baseline, 6 months, and 12 months
Postoperative Analgesic Consumption
Postoperative analgesic consumption will be assessed by recording the total number of analgesic tablets taken by patients from the day of surgery through the 10th postoperative day.
Time frame: From the day of surgery through postoperative day 10 (11 days)
Ran from Dec 2022 to primary completion in Oct 2024, 22 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Bulent Ecevit University