An observational study in Depressed, sponsored by University of Calgary. Not yet recruiting at 1 site in Canada. Open to female participants aged 12 Years to 18 Years. Per ClinicalTrials.gov, last updated 2026-01-05.
Sponsored by University of Calgary · Observational
The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is:
Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.
235 studies on the registry are indexed under Consciousness Disorders; 101 are open to participants now.
This study's planned enrollment of 94 is above the median of 79 across 86 observational studies indexed under Consciousness Disorders.
Browse Consciousness Disorders studies →University of Calgary is the lead sponsor of 686 studies on the registry; 189 are open to participants now.
Of its 10 completed or terminated interventional studies of FDA-regulated products, 2 (20%) have results posted.
Counted across the registry records on this site, refreshed daily.
Depressed, naturally cycling adolescents assigned female at birth.
Exclusion Criteria:
Main study cohort
Identification ovarian hormone affect sensitivity
Identify depressed adolescents assigned female at birth with depressed affect sensitivity to changes in ovarian hormones across the menstrual cycle.
Time frame: 90 days
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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University of Calgary