An observational study in Rheumatoid Arthritis (RA and Atherosclerotic Cardiovascular Disease (ASCVD), sponsored by Brigham and Women's Hospital. Recruiting at 3 sites in United States. Open to participants aged 35 Years to 79 Years. Per ClinicalTrials.gov, last updated 2026-07-14.
Sponsored by Brigham and Women's Hospital · Observational
Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.
The objective of this study is to test the utility of high sensitivity cardiac troponin (hs-cTn) and coronary artery calcium (CAC) in risk stratifying patients with rheumatoid arthritis (RA) who may benefit from lipid lowering therapy. The population of interest are individuals who would not otherwise be recommended for therapy based on general population risk calculators for heart disease risk.
2,888 studies on the registry are indexed under Arthritis, Rheumatoid; 390 are open to participants now.
This study's planned enrollment of 120 is below the median of 176 across 824 observational studies indexed under Arthritis, Rheumatoid.
Browse Arthritis, Rheumatoid studies →Brigham and Women's Hospital is the lead sponsor of 1,236 studies on the registry; 224 are open to participants now.
Of its 116 completed or terminated interventional studies of FDA-regulated products, 64 (55%) have results posted.
Counted across the registry records on this site, refreshed daily.
Adult patients with rheumatoid arthritis, age 40- 79 years, with one cardiovascular risk factor and not on a statin or has a contraindication to statin therapy.
Exclusion Criteria:
Blood measurement of high sensitivity cardiac troponin
coronary artery calcium score
Quantified coronary artery calcium score
Time frame: Cross-sectional, at baseline
Plan to share: Undecided — Pending IRB approval.
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Brigham and Women's Hospital