ClinicalTrials.gg
RecruitingNCT07312994Updated Dec 31, 2025

Analysis of NfL and GFAP in Different Dietary Patterns

An observational study in Neurofilament Light Chain, Glial Fibrillary Acidic Protein and GFAP, sponsored by Salzburger Landeskliniken. Recruiting at 1 site in Austria. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-31.

Sponsored by Salzburger Landeskliniken · Observational

From the registry’s dates

  • Primary completion was expected by Apr 2026, 7 months ago, but the record still lists the study as recruiting.
  • Started Dec 2025; still recruiting 10 months later.
Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
300
Ages
18 Years to 40 Years
Sex
All
01

Study summary

This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP.

The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels?

02

Conditions studied

  • Neurofilament Light Chain
  • Glial Fibrillary Acidic Protein
  • GFAP
  • Vegan Diet
  • Vegetarian Diet
03

In context

Lead sponsor

Salzburger Landeskliniken is the lead sponsor of 15 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Young and healthy individuals aged between 18 and 40 years

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Healthy individuals who have followed a vegan, vegetarian, or omnivorous diet for at least one consecutive year
  • Aged between 18 and 40 years
  • Provision of written

Exclusion criteria

Exclusion Criteria:

  • Diagnose neurological disorders (e.g. neurodegenerative, inflammatory, , infectious, vascular)
  • Eating disorders
  • Excessive alcohol consumption
  • Pregnancy
  • Recent moderate to severe infection (within the past 12 weeks) , including SARS-CoV-2
  • Recent trauma, injury, or surgery (within the past 12 weeks)
  • Significant fluctuations (>5 points) within the last year
  • Patients who have been using Proton pump inhibitors (PPIs) for an extended period (e.g., 1 month).
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Autoimmune disease

A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.

Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
300 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • Omnivore
  • Vegan
  • Vegetarian
06

What researchers measure

Primary outcomes

  1. Blood levels of the following biomarkers: neurofilament light chain (NfL) in pg/mL, glial fibrillary acidic protein (GFAP) in pg/mL.

    Time frame: Once at baseline

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 31, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07312994
Lead sponsor
Salzburger Landeskliniken
Collaborators
Medizinische Einrichtungen der Universität Düsseldorf, Medizinische Fakultät der Universität zu Köln, Universitätsklinkum Münster - Medizinische Klinik und Poliklinik B
Responsible party
Tobias Moser (apl. Prof., Salzburger Landeskliniken) — Principal investigator
First posted
Dec 31, 2025
Start date
Dec 18, 2025
Primary completion
Apr 2026 (estimated)
Completion
Sep 2026 (estimated)
Last update
Dec 31, 2025

Study contacts

Tobias Moser, Prof.
Contact
t.moser@salk.at
+435725534720

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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