An observational study in Computed Tomography, Coronary Angiography and Incidental Findings, sponsored by Jordan Collaborating Cardiology Group. Not yet recruiting at 1 site in Jordan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-30.
Sponsored by Jordan Collaborating Cardiology Group · Observational
Coronary CT angiography (CCTA) is increasingly used for ischemic heart disease diagnosis. The rising number of CCTA tests has led to a significant increase in the number of finding unexpected incidental extracardiac diseases.
The increasing utilization of coronary computed tomography (CT) angiography (CCTA) to diagnose and triage patients with suspected or known ischemic heart disease has led to a parallel increase in the frequency of incidental findings in the coronaries (nonatherosclerotic), noncoronary cardiac structures and noncardiac structures.
Studies have reported a prevalence of incidental findings on CCTA up to 40%. Most of these findings have no clinical relevance, but some have significant clinical implications in the care and prognosis of the patients.
We sought to assess the frequency of incidental findings on CCTA scans in consecutive studies performed in the past 5 years.
4,857 studies on the registry are indexed under Coronary Artery Disease; 890 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 320 across 1,687 observational studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →Jordan Collaborating Cardiology Group is the lead sponsor of 26 studies on the registry; 7 are open to participants now.
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Exclusion Criteria:
All adults (18 years of age and older0 who underwent CCTA to evaluate the coronary arteries in the past 5 years will have their CT scans reviewed for the presence of non coronary incidental findings.
Diagnostic Test: CCTA (Review of the scans)
Reviewing coronary scans done in the past 5 years looking for findings other than atherosclerotic coronary artery disease.
Non atherosclerotic coronary disease
Findings other than coronary atherosclerotic disease: coronary bridge, coronary dissection, coronary embolism, and coronary fistula.
Time frame: BASELINE
Non coronary cardiac findings
Findings include valve calcifications, left atrial appendage thrombus, patent foramen ovale and septal defects, pericardial effusion, LV clots, cardiac tumors.
Time frame: BASELINE
Non cardiac findings
Non cardiac findings include: a. major vascular abnormalities in the aorta and the pulmonary arteries, b. pulmonary disease: masses, lymph nodes, granulomas, and pleural effusion, and c. non pulmonary findings in the diaphragm and the hepatobiliary tree.
Time frame: BASELINE
Plan to share: Yes — The excel sheet of the incidental findings in the 2000 CCTA scans in possession of the investigators will be available to any physician upon request
Supporting information: Study protocol, Statistical analysis plan
No publications or documents are linked to this record.
Start is estimated for Jan 2026; primary completion for Jan 2027, 12 months later.
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This study is not yet recruiting, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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Jordan Collaborating Cardiology Group