An interventional study of Arterial Blood gases in Preeclampsia and Severe Preeclampsia, sponsored by Saint Thomas Hospital, Panama. Completed at 1 site in Panama. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-16.
Sponsored by Saint Thomas Hospital, Panama · Not applicable, Interventional, and Diagnostic
The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals. Researchers will measure these values using an arterial blood gas test before delivery or surgery.
This is a prospective cohort study. The researchers will analyze various blood gas parameters, including pH, lactate, and BE, and then correlate the BE values with clinical variables and negative maternal outcomes.
The expected outcome is that a abnormal BE values will be linked to a greater severity of preeclampsia. If this association is confirmed, BE could serve as an additional marker for predicting the severity of the condition and may lay the groundwork for future research on diagnostic and therapeutic standards based on blood gas analysis.
916 studies on the registry are indexed under Pre-Eclampsia; 243 are open to participants now.
This study's enrollment of 100 is close to the median of 110 across 480 interventional studies indexed under Pre-Eclampsia.
Browse Pre-Eclampsia studies →Saint Thomas Hospital, Panama is the lead sponsor of 37 studies on the registry; 3 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Pregnant subjects with severe preeclampsia
Diagnostic Test: Arterial Blood gases
Pregnant subjects with normal blood pressure
Diagnostic Test: Arterial Blood gases
Determination of Excess Base in arterial blood gases before delivery / termination of pregnancy
Value of excess base
Total measure of excess base measured by gasometry in an arterial blood sample
Time frame: Immediately before delivery
Hypertensive crisis
Elevation of the blood pressure above 160 (systolic) and 110 (diastolic).
Time frame: From admission to day three (3) after delivery
Lactate
Concentration of lactate measured by gasometry in a sample of arterial blood.
Time frame: Immediately before delivery
Bicarbonate
Concentration of bicarbonate measured by gasometry in arterial blood gases
Time frame: Immediately before delivery
Plan to share: No
No publications or documents are linked to this record.
Ran from Aug 2025 to primary completion in Feb 2026, 6 months.
Of 171 non-industry interventional studies with no phase under Pre-Eclampsia, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 43. This study's 6 months is below that.
Counting every sponsor, half of 176 studies reached it within 24 months; a quarter within 9 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Saint Thomas Hospital, Panama