ClinicalTrials.gg
RecruitingNCT07243054PERLEUpdated Nov 21, 2025

Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life

An observational study in Vascular Filling, Newborn and Weight Loss, sponsored by Centre Hospitalier Universitaire, Amiens. Recruiting at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-21.

Primary conditionJaundiceRegistry: Weight LossReclassifiedWhy we changed it
Registry
Weight Loss — the first condition term the registry derived for this study.
ClinicalTrials.gg
Jaundice
Why
  1. Weight Loss is a broad heading, used only when no more specific condition is named.
  2. The study's listed conditions name Jaundice.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Centre Hospitalier Universitaire, Amiens · Observational

From the registry’s dates

  • Primary completion was expected by Nov 2025, 1 year ago, but the record still lists the study as recruiting.
  • Started Mar 2025; still recruiting 1 year 8 months later.
Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
200
Ages
18 Years and older
Sex
Female
01

Study summary

At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula.

This observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn.

The investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.

02

Conditions studied

  • Vascular Filling
  • Newborn
  • Weight Loss
  • Jaundice
  • Respiratory Distress

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Keywords

  • vascular filling
  • newborn
  • weight loss
  • jaundice
  • respiratory distress
03

In context

Jaundice Reclassified

84 studies on the registry are indexed under Jaundice; 13 are open to participants now.

This study's planned enrollment of 200 is close to the median of 200 across 31 observational studies indexed under Jaundice.

Browse Jaundice studies →

Lead sponsor

Centre Hospitalier Universitaire, Amiens is the lead sponsor of 586 studies on the registry; 185 are open to participants now.

Compared within Jaundice, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Weight Loss. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Mother over 18 years of age and newborn

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Full-term delivery (≥37+0 SA)
  • Singleton pregnancy
  • Mother over 18 years of age
  • Infant formula feeding exclusively in the maternity ward for the first 2 days

Exclusion criteria

Exclusion Criteria:

  • Mother under guardianship
  • Mother who does not understand French
  • Mother objecting to her personal data being reused for research purposes
  • Incomplete or incorrectly completed patient medical record
  • Mixed or exclusive breastfeeding
  • Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason
  • Child with renal pathology or uropathy
  • Children with cleft lip, palate or labio-palate
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Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
200 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Correlation between maternal vascular fluid loading and newborn infant weight loss

    Time frame: 2 days

Secondary outcomes

  1. Correlation between maternal vascular fluid loading and respiratory distress

    Time frame: 2 days

  2. Correlation between maternal vascular fluid loading and jaundice of the newborn

    Time frame: 2 days

07

Study locations

1 of 1 sites recruiting
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 21, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07243054
Responsible party
Sponsor
First posted
Nov 21, 2025
Start date
Mar 1, 2025
Primary completion
Nov 2025 (estimated)
Completion
Nov 2025 (estimated)
Last update
Nov 21, 2025

Study contacts

Pierre Tourneux, Pr
Contact
Tourneux.Pierre@chu-amiens.fr
33+3 22 08 76 04

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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