ClinicalTrials.gg
Enrolling by invitationNCT07239167Updated Sep 15, 2026

A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change

An observational study in Obesity & Overweight, Weight Loss and Metabolic Syndrome, sponsored by National Taiwan University Hospital. Enrolling by invitation at 1 site in Taiwan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-15.

Sponsored by National Taiwan University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
500
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 19 studies in Obesity by National Taiwan University Hospital — 8 open to participants now, 8 under way, none of them phase 3. Obesity · National Taiwan University Hospital.

Started
2025
with 4 others
Observational
11 of 19
4 open now
Registered
14th of 19
by date

Among the 19 studies in Obesity by National Taiwan University Hospital, this one is one of 5 that started in 2025, is one of 11 observational ones, and was the 14th registered.

By phase

19 studies; the count open now beside each. This study's row is marked.

Observationalthis study11 · 4 open
No phase8 · 4 open

By the year they started

First in 2004; this study’s year is marked. 5 started in 2025.

What they test

Size and results

Median enrollment 182 across the 8 interventional studies, 289 across the 9 observational. Of the 6 that completed or were terminated, 0 (0%) have results posted.

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Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 19 studies in Obesity by National Taiwan University Hospital, or all of them as a file.
02

Study summary

This prospective cohort study collected baseline data and followed up obese patients at their first visit to a weight loss clinic. The study examined the impact of various predictors and biomarkers on weight loss outcomes, aiming to establish an evidence-based foundation for personalized weight loss treatment.

Participants underwent a battery of measurements and questionnaires, including height, weight, waist circumference, blood pressure, blood tests, and questionnaires addressing diet, exercise, stress, sleep, measure handgrip strength ,and psychological well-being.

03

Conditions studied

  • Obesity & Overweight
  • Weight Loss
  • Metabolic Syndrome
  • Metabolic Dysfunction-Associated Steatohepatitis
  • Obesity (Disorder)
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Participate were first diagnosed at the weight loss clinic at the National Taiwan University Hospital.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Adults aged 18 years or older, regardless of gender.
  2. (BMI) ≥ 27 kg/m², or ≥ 24 kg/m² with one or more obesity-related comorbidities.
  3. Willing to undergo any form of weight loss intervention.
  4. Able to read and understand Chinese, willing to complete questionnaires, blood tests, and follow-up follow-up.
  5. Voluntarily consent to participate and be willing to complete the subject consent form.

Exclusion criteria

Exclusion Criteria:

  1. Pregnant or breastfeeding women.
  2. Individuals with significant mental illness (e.g., schizophrenia, severe depression) or cognitive impairment that may affect their ability to consent or cooperate with the study.
  3. Individuals with severe organ dysfunction (e.g., end-stage renal disease, cirrhosis, congestive heart failure, etc.).
  4. Individuals taking medications that significantly affect their weight (e.g., long-term or antipsychotics) and cannot be discontinued.
  5. Individuals deemed unsuitable for participation in this study by the study leader (e.g., individuals who are expected to be unable to complete follow-up).
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
500 participants (estimated)
Target follow-up
2 Years
Patient registry
Yes

Groups and cohorts

  • A prospective cohort study on patients with obesity undergoing weight change
06

What researchers measure

Primary outcomes

  1. Baseline data were collected and followed up during the subjects' initial visit to the weight loss clinic to establish an evidence-based basis for personalized weight reduction treatment.

    Time frame: Weight changes of subjects after 24 weeks, 48 weeks, 72 weeks, and 96 weeks.

07

Study locations

1 site
  • No.7, Chung Shan S. Rd.(Zhongshan S. Rd.)
    Taipei, Zhongzheng Dist 100, Taiwan
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jun 2025 (actual). Primary completion is estimated for Apr 2027, 22 months after the start.

Of 791 non-industry observational studies under Obesity, half reached primary completion within 40 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 106. This study's planned 22 months is below that.

Counting every sponsor, half of 836 studies reached it within 39 months; a quarter within 17 and three quarters within 96.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 16, 2025
First posted
Nov 20, 2025
StartActual
Jun 5, 2025
Primary completionEst.
Apr 8, 2027
CompletionEst.
May 5, 2035
Last update
Sep 15, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 15, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07239167
Responsible party
Sponsor
First posted
Nov 20, 2025
Start date
Jun 5, 2025
Primary completion
Apr 8, 2027 (estimated)
Completion
May 5, 2035 (estimated)
Last update
Sep 15, 2026
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

No contact was published for this record. The registry link below has the sponsor’s details.

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Discussion

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