CClinicalTrials.gg
Sign In
Enrolling by invitationNCT07239167Updated Sep 15, 2026

A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change

An observational study in Obesity & Overweight, Weight Loss and Metabolic Syndrome, sponsored by National Taiwan University Hospital. Enrolling by invitation at 1 site in Taiwan. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-15.

Sponsored by National Taiwan University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
500
Ages
18 Years and older
Sex
All
01

Study summary

This prospective cohort study collected baseline data and followed up obese patients at their first visit to a weight loss clinic. The study examined the impact of various predictors and biomarkers on weight loss outcomes, aiming to establish an evidence-based foundation for personalized weight loss treatment.

Participants underwent a battery of measurements and questionnaires, including height, weight, waist circumference, blood pressure, blood tests, and questionnaires addressing diet, exercise, stress, sleep, measure handgrip strength ,and psychological well-being.

02

Conditions studied

  • Obesity & Overweight
  • Weight Loss
  • Metabolic Syndrome
  • Metabolic Dysfunction-Associated Steatohepatitis
  • Obesity (Disorder)
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Participate were first diagnosed at the weight loss clinic at the National Taiwan University Hospital.

Inclusion criteria

  1. Adults aged 18 years or older, regardless of gender.
  2. Body mass index (BMI) ≥ 27 kg/m², or ≥ 24 kg/m² with one or more obesity-related comorbidities.
  3. Willing to undergo any form of weight loss intervention.
  4. Able to read and understand Chinese, willing to complete questionnaires, blood tests, and follow-up follow-up.
  5. Voluntarily consent to participate and be willing to complete the subject consent form.

Exclusion criteria

Exclusion Criteria:

  1. Pregnant or breastfeeding women.
  2. Individuals with significant mental illness (e.g., schizophrenia, severe depression) or cognitive impairment that may affect their ability to consent or cooperate with the study.
  3. Individuals with severe organ dysfunction (e.g., end-stage renal disease, cirrhosis, congestive heart failure, etc.).
  4. Individuals taking medications that significantly affect their weight (e.g., long-term steroids or antipsychotics) and cannot be discontinued.
  5. Individuals deemed unsuitable for participation in this study by the study leader (e.g., individuals who are expected to be unable to complete follow-up).
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
500 participants (estimated)
Target follow-up
2 Years
Patient registry
Yes

Groups and cohorts

  • A prospective cohort study on patients with obesity undergoing weight change
05

What researchers measure

Primary outcomes

  1. Baseline data were collected and followed up during the subjects' initial visit to the weight loss clinic to establish an evidence-based basis for personalized weight reduction treatment.

    Time frame: Weight changes of subjects after 24 weeks, 48 weeks, 72 weeks, and 96 weeks.

06

Study locations

1 site
  • No.7, Chung Shan S. Rd.（Zhongshan S. Rd.）
    Taipei, Zhongzheng Dist 100, Taiwan
07

Registry details

Key details

Study ID
NCT07239167
Lead sponsor
National Taiwan University Hospital
Responsible party
Sponsor
First posted
Nov 20, 2025
Start date
Jun 5, 2025
Primary completion
Apr 8, 2027 (estimated)
Completion
May 5, 2035 (estimated)
Last update
Sep 15, 2026
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

No contact was published for this record. The registry link below has the sponsor’s details.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Obesity→

Other studies from this sponsor

National Taiwan University Hospital

Start the discussion