An interventional study of Jaspr and Behavioral support in Suicidal Ideation, Suicide Attempt and Self-Harm, sponsored by University of Massachusetts, Amherst. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-10-20.
Sponsored by University of Massachusetts, Amherst · Not applicable, Interventional, and Treatment
Mobile-based applications, such as JasprHealth, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories), but user engagement is a barrier. The aim of this study was to examine the effects of a technological application resource (Jaspr) relative to human augmentation (Jaspr+, e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among college students who screen positive for suicide risk.
Mobile-based applications, such as Jaspr Health, can deliver evidence-based skills intended to reduce imminent suicide risk (e.g., reducing means access), improve emotional states (e.g., via distraction and coaching to act opposite to emotions), and reduce feelings of social isolation (e.g., via shared stories). Although mobile-device-delivered interventions hold the potential to make interventions widely accessible, user engagement presents a substantial barrier to efficacy. This study, ASSIST: Advancing Student Suicide Interventions with Scalable Technologies, aims to improve engagement with mobile-delivered suicide prevention applications, with the ultimate goal of reducing suicidal thoughts and behaviors in college students. Including human elements alongside Jaspr Health has the potential to improve the uptake of this evidence-based, accessible mobile-device-delivered intervention.
The aim of this study was is to examine the effects of the technological application resource Jaspr tablet application with access to Jaspr at Home (JAH) vs. Jaspr+ human augmentation (e.g., motivationally focused orientation plus prompts) on acceptability, preliminary effectiveness, and engagement among 50 college students who screen positive for suicide risk (n=25 per condition) over the course of 2 months. Candidate mechanisms (e.g., coping skills, self-stigma) will also be assessed. Participants were randomized via the Redcap randomization module, stratified by site.
569 studies on the registry are indexed under Suicidal Ideation; 203 are open to participants now.
This study's planned enrollment of 50 is below the median of 80 across 469 interventional studies indexed under Suicidal Ideation.
Browse Suicidal Ideation studies →University of Massachusetts, Amherst is the lead sponsor of 48 studies on the registry; 5 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Subjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library. Subjects can sign up to receive Jaspr At Home (JAH) mobile app. Subjects will have continue to have access to treatment as usual through their respective university clinics.
Device: Jaspr
Subjects in this arm will complete a guided Safety Planning, and Lethal means counseling on the Jaspr app before open access to the Jaspr resource library. This will be guided by motivational interviewing principles. Subjects can sign up to receive Jaspr At Home (JAH0 mobile app. Subjects will be prompted with their personalized goals as reminders to use the Jaspr at home app. Subjects will have continue to have access to treatment as usual through their respective university clinics.
Device: Jaspr · Behavioral: Behavioral support
With assistance from a research staff, the subject will complete self-administered suicide risk assessment on the tablet via Jaspr app, then the subject will engage with suicide-related coping skills and resources that the app provides. Subjects will continue to have access to the coping skills and videos via a mobile app.
Jaspr conversations will be augmented human-driven behavioral support. Conversations will be guided by motivational interviewing principles. Subjects can sign up to receive JAH mobile app. Subjects will be prompted with their personalized goals as reminders to use the Jaspr app.
Suicidal ideation
Assessed with Suicide Ideation Questionnaire \[SIQ\], with higher scores reflecting greater past month suicidal ideation.
Time frame: weeks 0, 4, 8
Suicidal behaviors
Assessed with the Columbia-Suicide Severity Rating Scale \[C-SSRS\] self-report screen past week (y = presence /n)
Time frame: weeks 0, 1, 2, 3, 4, 8
Suicide-related coping
Assessed with the suicide-related coping scale, \[SRCS\] with higher scores reflecting a better ability to cope with suicidal thoughts
Time frame: weeks 0, 4, 8
Ways of coping
Assessed with the DBT-Ways of Coping Checklist (DBT-WCCL), which yields scales of skills use, general dysfunctional coping, and blaming others, with mean scores of 0-3, with higher levels indicating greater use of those strategies.
Time frame: weeks 0, 4, 8
Suicide stigma
Assessed with the personal suicide stigma questionnaire \[PSSQ\], with higher scores reflecting greater stigma.
Time frame: weeks 0, 4, 8
Self-reported engagement
Assessed with item developed for this study, with higher scores reflecting greater engagement in the app.
Time frame: weeks 0, 1, 2, 3, 4, 8
Acceptability
Assessed with the Acceptability of Implementation Measure \[AIM\], with higher scores reflecting whether the intervention is liked, welcomed, or approved.
Time frame: weeks 0, 4, 8
Satisfaction with Intervention
Assessed with the Client Satisfaction Questionnaire - 8 \[CSQ8\], with higher scores reflecting greater satisfaction with the intervention.
Time frame: weeks 0, 4, 8
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Yes — The analytic plan and de-identifiable/de-identified data will be shared.
Supporting information: Statistical analysis plan
Time frame: Data are expected to be cleaned scored and uploaded by Jan 2028 for at least 7 years.
Access criteria: Data will be available from the researchers upon request
Started Oct 2025 (actual). Primary completion is estimated for Jun 2027, 20 months after the start.
Of 281 non-industry interventional studies with no phase under Suicidal Ideation, half reached primary completion within 30 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 54. This study's planned 20 months is below that.
Counting every sponsor, half of 290 studies reached it within 29 months; a quarter within 13 and three quarters within 53.
How these figures are worked out, and which studies are left out of them.
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University of Massachusetts, Amherst