CClinicalTrials.gg
CompletedNCT07203430Updated Apr 14, 2026

Biopsychosocial Factors and Muscle Morphology After a Resistance Exercise

An interventional study of 45-Degree Roman Chair Exercise in Low Back Pain, Chronic, sponsored by University of Central Florida. Completed at 1 site in United States. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-04-14.

Sponsored by University of Central Florida · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
22
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The purpose of this study is to evaluate the longitudinal effects of a four-week dynamic resistance training program using the 45-degree Roman chair on pain sensitivity changes after exercise and lumbar muscle performance in individuals with chronic low back pain (LBP). This study will consist of three specific aims. Aim 1 examines changes in local exercise-induced hypoalgesia. Aim 2 will assess changes in lumbar multifidus and erector spinae thickness using ultrasound imaging before and after the intervention. Aim 3 will evaluate changes in lumbar extensor strength (handheld dynamometry (HHD)) and endurance (Biering-Sørensen test).

02

Conditions studied

  • Low Back Pain, Chronic

Keywords

  • Exercise
  • Low Back Pain
03

In context

Low Back Pain

2,820 studies on the registry are indexed under Low Back Pain; 482 are open to participants now.

This study's enrollment of 22 is below the median of 60 across 2,268 interventional studies indexed under Low Back Pain.

Browse Low Back Pain studies →

Lead sponsor

University of Central Florida is the lead sponsor of 99 studies on the registry; 40 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • chronic low back pain lasting ≥ 12 weeks
  • current pain intensity ≥ 3/10 but no higher than an 8/10 on the Numeric Pain Rating Scale (NPRS) within the past 48 hours
  • resistance trained (defined as 2x/week for the past 8-12 weeks)
  • able to read and speak English for informed consent and completion of questionnaires
  • willing and physically able to complete all testing and intervention sessions.

Exclusion criteria

Exclusion Criteria:

  • History of spinal surgery, fusion, or fracture within the past 6 months
  • diagnosed degenerative disc disease, scoliosis, or spinal pathology that precludes safe exercise participation
  • use of an assistive device for walking (cane, walker) within the past year
  • pregnancy, due to contraindications for exercise testing and ultrasound -body weight ≥ 300 lbs., which exceeds the safe capacity of the Roman chair --
  • current tobacco/nicotine use
  • current enrollment in physical therapy or structured rehabilitation for LBP,
  • cardiovascular, pulmonary, metabolic, or systemic disease that increases risk during exercise
  • nociplastic pain conditions (e.g., fibromyalgia) or neurological conditions that confound EIH responses
  • inability to complete ≥ 8 Roman chair repetitions with proper form during screening
  • non-English speaking
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
22 participants (actual)

Study arms

  • Experimental
    Intervention Group

    During visits 2-13, participants will attend 2-3 sessions per week, with a minimum of 48 hours between visits, and must complete all study visits 6 weeks after enrollment. Participants in the intervention group will perform 3 sets of low back extension exercise on the Roman chair until volitional exhaustion. The three sets will be performed to volitional exhaustion or 20 repetitions, whichever comes first. If more than 20 repetitions can be completed after a set the investigator will add resistance according to the NSCA's guidelines (2.5-10% increase).

    Other: 45-Degree Roman Chair Exercise

  • No intervention
    Control Group

    Participants in the control group will not complete the low back extension exercise and will be told to continue activity as usual. All participants will complete a training log and detail the type of resistance exercise performed, the number of sets and repetitions completed, and the weight used.

Interventions

  • Other45-Degree Roman Chair Exercise

    Participants in the intervention group will perform 3 sets of low back extension exercise on the Roman chair until volitional exhaustion. The three sets will be performed to volitional exhaustion or 20 repetitions, whichever comes first. If more than 20 repetitions can be completed after a set the investigator will add resistance according to the NSCA's guidelines (2.5-10% increase).

06

What researchers measure

Primary outcomes

  1. Exercise Induced Hypoalgesia

    Participants will perform one set of back extension exercise on a 45-degree Roman chair until volitional exhaustion. Pressure Pain Threshold applied over the low back will be examined before and after exercise.

    Time frame: Weeks 1 and 4

  2. Muscle Thickness

    Ultrasound imaging to assess muscle thickness of the erector spinae and the multifidus muscles will be completed.

    Time frame: Weeks 1 and 4

  3. Muscle Strength

    Back extensor strength will be assessed using maximal voluntary isometric contraction of the back extensor muscles using a handheld dynamometer.

    Time frame: Weeks 1 and 4

  4. Muscle Endurance

    The Biering-Sorensen test will be performed in which participants lie prone on a treatment table with the lower body secured to the table. Participants will be instructed to cross their arms over their chest and maintain their torso in a horizontal position with the upper body unsupported, parallel to the floor.

    Time frame: Weeks 1 and 4

07

Study locations

1 site
  • University of Central Florida
    Orlando, Florida 32816, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 14, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07203430
Lead sponsor
University of Central Florida
Responsible party
Abigail Wilson (Assistant Professor, University of Central Florida) — Principal investigator
First posted
Oct 2, 2025
Start date
Oct 15, 2025
Primary completion
Apr 9, 2026
Completion
Apr 9, 2026
Last update
Apr 14, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion