CClinicalTrials.gg
RecruitingNCT07201194Updated May 28, 2026

Holistic Acupuncture for Patients With Chemotherapy Induced Nausea

An interventional study of Holistic acupuncture and acupressure and Standard medical treatment in Breast Cancer, Prostate Cancer and Lung Cancer, sponsored by Vejle Hospital. Recruiting at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-28.

Sponsored by Vejle Hospital · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The study explores whether acupuncture as a supplement to conventional antiemetic medicine is superior in reducing the level of chemotherapy induced nausea compared to conventional anitemetic medicine alone.

A total of 90 patients experiencing chemotherapy induced nausea will be allocated 1:1 to either acupuncture and antiemetic medicine or antiemetic medicine alone.

The level of nausea and other cancer related symptoms will be assessed at baseline and 8 and 22 days after enrollment

02

Conditions studied

  • Breast Cancer
  • Prostate Cancer
  • Lung Cancer
  • Gynaecologic Cancer
  • Colorectal Cancer
  • Pancreatic Cancer Metastatic

Keywords

  • acupuncture
  • chemotherapy induced nauseau
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • ≥ 18 years of age
  • Undergoing chemotherapy and experiencing nausea despite adherence to the prescribed antiemetic regimen
  • Understands and speaks Danish
  • Written and orally informed consent
  • Planned for treatment every 14 days
  • At least two chemotherapy cycles planned at the time of inclusion

Exclusion criteria

Exclusion Criteria:

  • Brain metastases
  • Performance status >2
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
90 participants (estimated)

Study arms

  • Experimental
    Holistic acupuncture and acupressure

    Holistic acupuncture and acupressure as a supplement to standard care

    Other: Holistic acupuncture and acupressure

  • Active comparator
    Standard care

    Other: Standard medical treatment

Interventions

  • OtherHolistic acupuncture and acupressure

    The intervention consists of one holistic and individualized consultation with an oncologist trained in acupuncture, in connection with outpatient chemotherapy. The consultation follows the principles of Traditional Chinese Medicine (TCM). The theoretical framework applied is Zang-Fu, which describes organ imbalances and aligns closely with Western medical understanding. Based on individual assessment and anamnesis, the patient receives acupuncture combined with acupressure. A maximum of 10 needles will be used, regardless of whether a deficiency or excess condition is identified. The acupuncture needles used are CAIR Super Silicon CSC-1, size 0.20 × 25 mm. The needles are inserted perpendicularly, except for Yin Tang, which is inserted transversely. The needles will remain in place for 25 minutes.

  • OtherStandard medical treatment

    Standard treatment and care includes chemotherapy, supportive antiemetic medication, close monitoring, and management of the patient's symptoms, side effects, and overall health.

05

What researchers measure

Primary outcomes

  1. Patient reported nausea assessed on the EORTC-15-PAL Scale

    Time frame: 8 days after enrollment

Secondary outcomes

  1. Patient reported symptom intensity according to the EORTC-15 PAL Scale

    Time frame: 8 and 22 days after enrollment

Other outcomes

  1. Patient reported use of antiemetic medicine

    Time frame: 8 and 22 days after enrollment

06

Study locations

1 of 1 sites recruiting
  • Department of Oncology, Vejle Hospital
    Vejle, 7100, Denmark
    Recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07201194
Lead sponsor
Vejle Hospital
Responsible party
Sponsor
First posted
Oct 1, 2025
Start date
Nov 17, 2025
Primary completion
Apr 2027 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
May 28, 2026

Study contacts

Mette Stie, PhD
Contact
mette.stie@rsyd.dk
+4579409174
Nanna Nordestgaard Madsen, MScN
Contact
nanna.nordestgaard.madsen@rsyd.dk
+4579406095
Mette Stie, Phd
principal investigator · Department of Oncology, Lillebaelt Hospital, Vejle

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion