ClinicalTrials.gg
CompletedNCT07200492Updated Oct 1, 2025

Anti-Redness Clinical Study

An interventional study of Facial serum application and Forearm serum application in Redness, sponsored by ChinaNorm. Completed at 1 site in China. Open to female participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-10-01.

Sponsored by ChinaNorm · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 1 year 7 months after the study started (first participant enrolled Jan 2024, registered Sep 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
32
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
Female
01

Study summary

This clinical study is a single-center, randomized, split-face, on-site controlled trial conducted at Shanghai China-Norm Quality Technical Service Co., Ltd. The primary objective is to evaluate the efficacy of Eucerin Ultrasensitive Repair Intensive Source Serum in providing instant and long-lasting (24-hour) soothing and repairing effects under induced redness conditions. The design involves recruiting 30 healthy Chinese female subjects aged 18-60 years, who meet stringent inclusion/exclusion criteria, including absence of skin conditions and no recent participation in similar studies. Redness is induced using 50% Glycolic Acid on the entire face and tape stripping on both forearms.

02

Conditions studied

  • Redness

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03

In context

Erythema

131 studies on the registry are indexed under Erythema; 17 are open to participants now.

This study's enrollment of 32 is below the median of 50 across 114 interventional studies indexed under Erythema.

Browse Erythema studies →

Lead sponsor

ChinaNorm is the lead sponsor of 30 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Chinese female whose age range from 18 to 60 years old;
  2. Be in general good health and good mental state;
  3. Have no any broken,scars,birthmarks and other imperfections on the test area;
  4. Redness/erythema≥grade 2 after modelling inducing and the score of redness must be increased after inducing;
  5. Not currently be participating in any other study involving the test area(Face and Forearm);
  6. Not have participated in any other study involving the test area in the past one month;
  7. Be willing to read,understand and able to sign the Form and Photo Release From;
  8. Be willing to comply with all study protocol requirements.

Exclusion criteria

Exclusion Criteria:

  1. Intending to get pregnant, be pregnant, be lactating, be within 6 months of delivery or be unwilling to take necessary precautions to avoid a pregnancy;
  2. Having used antihistamine drugs in the past 1 week or in the past 1 month;
  3. Taken anti-allergic drug/injections in the past 1 month;
  4. Presently have allergies, allergic dermatitis or skin disease;
  5. Have sensitivity or even allergy to topical products, ingredients or fragranced products;
  6. Have history of allergies;
  7. Have history of suffering from skin diseases (such as psoriasis, eczema, skin cancer, etc.);
  8. Have used any anti-inflammatory treatment on the test area within 2 months prior to this study starting date;
  9. Has a chronic medical condition that may interfere with testing (e.g., asthma, insulin-dependent diabetes, lupus, rheumatoid arthritis or other immune/auto-immune diseases);
  10. Have used any scrubs or peeling product (regardless of method) or self-tanning products or oil control products in the past 3 days;
  11. Have received cosmetic medical procedures on the face (such as injectable anti-wrinkle products, cosmetic surgery, tattoo removal, home light facial procedures or home use medical devices, etc.) in the past 1 month;
  12. Have excessive sun exposure or ultraviolet light exposure in the past 1 month;
  13. Have applied ortho-hydroxybenzoic acid, hydroquinone in the past 3 months; or used prescriptions (such as antibiotic, retinoids, alpha hydroxyl acid and ), oral ;
  14. Avoid providing emergency contact;
  15. Subjects that are not compliant with the selection criteria or not proper for participation as determined by Principal Investigator;
  16. An employee of the cosmetic companies or Shanghai China-Norm Quality technical service Co., Ltd.
Terms in these criteria, in plain language(4)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
32 participants (actual)

Study arms

  • Other
    Facial Test Arm

    Other: Facial serum application

  • No intervention
    Facial Control Arm
  • Other
    Arm Test Arm

    Other: Forearm serum application

  • No intervention
    Arm Control Arm

Interventions

  • OtherFacial serum application

    The trained technician will apply the 0.3g-0.4g investigational products on the subject's half face.

  • OtherForearm serum application

    The trained technician will apply the (2mg±0.1mg)/cm² investigational products on the subject's forearm.

06

What researchers measure

Primary outcomes

  1. Skin Erythema Index via Mexameter® MX 18

    Time frame: From Baseline to 24-hour after product repeat application

  2. Colorimetry (avalue) via Chromameter CM26dG *

    Time frame: from Baseline to 24-hour after product repeat application

  3. Skin Scaliness (Desquamation) via Squamescan® 850A

    Time frame: from Baseline to 24-hour after product repeat application

  4. Forearm Skin Redness (avalue) via Cross-Polarized Light Imaging *

    The a\*value is a parameter in the CIELAB color space (also known as Lab) that quantifies a color's position along the red-green axis .

    Time frame: From Baseline to 24-hour after product repeat application

  5. Facial Skin Redness and Colorimetry (a* value) via VISIA-CRP Imaging

    Time frame: from Baseline to 24-hour after product repeat application

  6. Skin Surface Evenness (SEsc) via UV Video Capture and SELS Analysis

    Time frame: from Baseline to 24-hour after product repeat application

07

Study locations

1 site
  • Shanghai China-norm Quality Technical Service Co., Ltd.
    Shanghai, Shanghai Municipality 200072, China
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jan 2024 to primary completion in Jan 2024, 0 months.

Of 43 interventional studies with no phase under Erythema, half reached primary completion within 3 months of starting (the median), counting those still running; a quarter within 1 and three quarters within 11. This study's 0 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 11, 2025
First posted
Oct 1, 2025
StartActual
Jan 15, 2024
Primary completionActual
Jan 22, 2024
CompletionActual
Jan 24, 2024
Last update
Oct 1, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Oct 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07200492
Lead sponsor
ChinaNorm
Responsible party
Sponsor
First posted
Oct 1, 2025
Start date
Jan 15, 2024
Primary completion
Jan 22, 2024
Completion
Jan 24, 2024
Last update
Oct 1, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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