An observational study in Oral Cancer, sponsored by National Taiwan University Hospital. Recruiting at 1 site in Taiwan. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-07-21.
Sponsored by National Taiwan University Hospital · Observational
The study aims to evaluate the morphological changes of upper trapezius muscle, using B-mode ultrasonography, in patients with oral cancer undergone neck dissection and physiotherapy. It also investigates the relationship between morphological changes and shoulder active range of motion in abduction. Furthermore , the study assesses the potential of B-mode ultrasonography as an objective tool for monitoring outcomes of the rehabilitation in this population.
The study aims to investigate the effect of 8-week physiotherapy on morphological change of upper trapezius muscle in oral cancer patients who have undergone neck dissection. Key outcome measurements include the muscle's thickness and cross-sectional area (CSA), measured via B-mode ultrasonography, as well as the active range of motion (AROM) in shoulder abduction. Neck dissections may result in spinal accessory nerve (CN XI) injury, often leading to shoulder pain, upper trapezius weakness and impaired shoulder mobility. Therefore, understanding the relationship between muscle thickness, CSA, and AROM is important. The study's goal is to explore the correlation between muscle morphological changes and functional outcomes, and further evaluate the role of B-mode ultrasonography as a non-invasive tool in monitoring muscle morphology in shoulder rehabilitation progress with post-surgical oral cancer patients with shoulder dysfunction.
377 studies on the registry are indexed under Mouth Neoplasms; 126 are open to participants now.
This study's planned enrollment of 10 is below the median of 90 across 103 observational studies indexed under Mouth Neoplasms.
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A total of 10 newly diagnosed oral cancer patients who received neck dissection with scapular dyskinesis
Exclusion Criteria:
Thickness and cross-sectional area of upper trapezius muscle
Cross-sectional area of upper trapezius muscle
CSA of the upper trapezius muscle is measured via B-mode panoramic ultrasonography. Panoramic B-mode ultrasonography will be performed by placing the probe at the spinous process of the fourth cervical vertebra (C4) and moving it laterally toward the posterior margin of the sternocleidomastoid muscle.
Time frame: Pre-intervention, 8 weeks post-intervention
Thickness of upper trapezius muscle
Thickness of upper trapezius muscle is measured via B-mode ultrasonography. The ultrasound probe will be positioned at the midpoint between the spinous process of the seventh cervical vertebra (C7) and the acromion, aligned parallel to the muscle fibers.
Time frame: Pre-intervention, 8 weeks post-intervention
Active range of motion in shoulder abduction
AROM in shoulder abduction is measured by a goniometer, with the fulcrum positioned over the anterior aspect of the acromial process. The proximal arm is aligned parallel to the midline of the anterior aspect of the sternum, while the distal arm is aligned with the anterior midline of the humerus.
Time frame: Pre-intervention, 8 weeks post-intervention
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National Taiwan University Hospital